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Human and Viral microRNA Expression in Acute and Chronic HIV Infections

Human and viral microRNAs (miRNAs) are involved in the regulation of gene transcription, and the establishment of their profiles in acute (AHI) and chronic (CHI) HIV infections may shed light on the pathogenetic events related to different phases of HIV disease. Next-generation sequencing (NGS) of miRNA libraries was performed, and the reads were used to analyze miRNA differential expression in the plasma with AHI and CHI. Functional analysis was then undertaken to investigate the biological ...

Rift Valley Fever Virus: An Overview of the Current Status of Diagnostics

Rift Valley fever is a vector-borne zoonotic disease caused by the Rift Valley fever virus (Phlebovirus genus) listed among the eight pathogens included in the Bluepoint list by the WHO. The transmission is mainly vehicled by Aedes and Culex mosquito species. Symptoms of the disease are varied and non-specific, making clinical diagnosis often challenging, especially in the early stages. Due to the difficulty in distinguishing Rift Valley fever from other viral hemorrhagic fevers, as well as m...

Selective Carbon Dioxide versus Nitrous Oxide Adsorption in Cerium(IV) Bithiazole and Bipyridyl Metal-Organic Frameworks

The two CeIV MOFs [Ce6O4(OH)4(TzTz)6] (Ce_TzTz) and [Ce6O4(OH)4(TzTz)4(PyPy)2] (Ce_TzTz_PyPy; H2TzTz = [2,2 '-bithiazole]-5,5 '-dicarboxylic acid, H2PyPy = 2,2 '-bipyridine-5,5 '-dicarboxylic acid) are prepared starting from a pre-formed [Ce6] glycinate-capped cluster. N2 isotherms collected at 77 K revealed BET specific surface areas of 1136 and 238 m2 g-1, respectively. Their CO2 and N2O adsorption capacity is assessed at T = 273 and 298 K and p = 1 bar. Ce_TzTz shows the highest gas uptake...

Of greater noctule “migration” from Russia to Italy: a comment on Vasenkov et al. (2023)

We comment on a recent study (Vasenkov et al. in Dokl Biol Sci 513:395–399, 2023, https://doi.org/10.1134/S0012496623700746) presenting the movement paths of three greater noctule bats (Nyctalus lasiopterus), two juveniles and an adult, tracked from Russia in September–October 2020 and 2021, with particular emphasis on the unprecedented straight-line migration of a juvenile male to Italy. Notably, the juvenile's extraordinary 2515 km migration marks the longest recorded (as the crow flie...

Thiazole-Decorated PCN-700 Metal-Organic Frameworks for Diclofenac Luminescence Sensing and Adsorption in Wastewater

The defective sites on the eight-connected [Zr6O4(OH)8(H2O)4]8+ nodes of the metal–organic framework (MOF) PCN-700 are the anchoring points for its postsynthetic decoration with extra linkers via solvent-assisted linker incorporation (SALI). The thiazolo[5,4-d]thiazole-2,5-dicarboxylic acid (H2TTz) and the newly prepared 2,2′-(1,4-phenylene)bis(4-methylthiazole-5-carboxylic acid) (H2TzPhTzMe) have been inserted into PCN-700 to obtain the mixed-linker MOFs (MIXMOFs) [TTz@PCN-700] (1) and [TzPh...

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