The events at the hydroxyapatite implant material/tissue interface following electromagnetic stimulation were studied in the rabbit. Two kinds of hydroxyapatite were used: natural (NA) and synthetic (HA) both with a grain size of <50 μm. Bone defects, artificially created in rabbit tibiae, were filled with the material examined. One group of animals was exposed immediately after surgery and every 12 h thereafter to 30-min treatments with electromagnetic fields (PEMFs). A second group was used as a control (untreated). Two and 4 weeks after implantation, animals were sacrificed and bone samples processed for LM, TEM and SEM using a backscatter electron detector for the evaluation of bone growth. This study indicates that HA has more osteoconductivity than NA, and shows that PEMF-treatment results in a benefit in accelerating bone formation at early time periods.
|Data di pubblicazione:||2002|
|Titolo:||Electromagnetic stimulation on the bone growth using backscattered electron imaging|
|Digital Object Identifier (DOI):||10.1016/S0968-4328(01)00008-7|
|Codice identificativo ISI:||WOS:000171809500003|
|Codice identificativo Scopus:||2-s2.0-0036027876|
|Parole Chiave:||Bone substitute, Hydroxyapatite, Osteogenesis, Magnetic field, Biomaterials, Interface, SEM|
|Appare nelle tipologie:||Articolo su Rivista|