Inorganic solid supports are useful media for the rapid and efficient synthesis of a library of quinoline-3,4-dicarboximides. In particular, wet clay K10 was shown to be the best medium for the condensation reaction between 2-methylquinoline3,4-dicarboxylic anhydride and several primary amines. Microwave irradiation is essential for a rapid and complete conversion.
Microwave-assisted solvent-free synthesis of a quinoline-3,4-dicarboximide library on inorganic solid supports
PIARULLI, UMBERTO;
2004-01-01
Abstract
Inorganic solid supports are useful media for the rapid and efficient synthesis of a library of quinoline-3,4-dicarboximides. In particular, wet clay K10 was shown to be the best medium for the condensation reaction between 2-methylquinoline3,4-dicarboxylic anhydride and several primary amines. Microwave irradiation is essential for a rapid and complete conversion.
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