Tuberculosis (TB) is a serious infection in immunocompromised patients, such as solid organ transplant recipients and HIV-infected patients. The diagnosis and treatment in this population present several challenges because of the aspecific clinical manifestations, the difficulty in diagnosis, and the choice of the most appropriate therapeutic regimen. Therapeutic challenges arise from drug-related toxicities, interactions between immunosuppressive, antiretroviral, and antituberculous drugs. We present a case of primary TB infection that occurred 3 years after transplantation in a HIV-and hepatitis C virus–coinfected kidney-pancreas recipient. The infection was successfully treated with no hepatotoxicity or rejection with a non-rifampin-containing regimen.
Pulmonary tuberculosis in an HIV- and hepatitis C virus–coinfected kidney-pancreas transplant recipient: a case report
DALLA GASPERINA, DANIELA;TOZZI, MATTEO;DIONIGI, RENZO;GROSSI, PAOLO ANTONIO
2011-01-01
Abstract
Tuberculosis (TB) is a serious infection in immunocompromised patients, such as solid organ transplant recipients and HIV-infected patients. The diagnosis and treatment in this population present several challenges because of the aspecific clinical manifestations, the difficulty in diagnosis, and the choice of the most appropriate therapeutic regimen. Therapeutic challenges arise from drug-related toxicities, interactions between immunosuppressive, antiretroviral, and antituberculous drugs. We present a case of primary TB infection that occurred 3 years after transplantation in a HIV-and hepatitis C virus–coinfected kidney-pancreas recipient. The infection was successfully treated with no hepatotoxicity or rejection with a non-rifampin-containing regimen.File | Dimensione | Formato | |
---|---|---|---|
Pulmonary_Tuberculosis_in_an_HIV-_and_Hepatitis_C_Virus-Coinfected_Kidney-Pancreas_Transplant_Recipient_-__A_Case_Report.pdf
non disponibili
Tipologia:
Documento in Post-print
Licenza:
DRM non definito
Dimensione
467.08 kB
Formato
Adobe PDF
|
467.08 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.