Lung interstitial diseases and bullae are described as possible complications of neurofibromatosis type-1 (NF-1), a genetic disorder inherited as a autosomal-dominant trait. We report the case of a 16-year-old male non-smoker with NF-1, who presented with pneumothorax caused by ruptured lung bullae. The case of this young patient, successfully treated by video-assisted thoracoscopic resection of bullae, supports the concept that pulmonary alterations may be part of the NF-1 syndrome, rather than as an unrelated complication.

Bullous lung disease and neurofibromatosis type-1.

IMPERATORI, ANDREA SELENITO;ROTOLO, NICOLA
2012-01-01

Abstract

Lung interstitial diseases and bullae are described as possible complications of neurofibromatosis type-1 (NF-1), a genetic disorder inherited as a autosomal-dominant trait. We report the case of a 16-year-old male non-smoker with NF-1, who presented with pneumothorax caused by ruptured lung bullae. The case of this young patient, successfully treated by video-assisted thoracoscopic resection of bullae, supports the concept that pulmonary alterations may be part of the NF-1 syndrome, rather than as an unrelated complication.
Nardecchia, Elisa; Perfetti, L; Castiglioni, M; Di Natale, D; Imperatori, ANDREA SELENITO; Rotolo, Nicola
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11383/1807321
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