The letter by Z.F. Udwadia and coworkers reports interesting data on the Indian experience in the treatment of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) with linezolid. The European Respiratory Journal has recently become a forum for discussing potentialities of this drug in the treatment of MDR-/XDR-TB cases by publishing the TBNET (Tuberculosis Network European Trials group) study on 85 cases performed in four European countries (including Belarus in Eastern Europe), the Indian experience presented by Z.F. Udwadia and co-workers from Mumbai, India of 18 cases, and the two case reports of YEW et al. regarding the use of linezolid 800 mg q.d. The aim of the present study is to discuss the key findings of the TBNET and Indian studies and to draw further conclusions, focusing on the available evidence on linezolid safety

From the authors: Assessment of linezolid efficacy and safety in MDR- and XDR-TB: an Indian perspective

SPANEVELLO, ANTONIO;
2010-01-01

Abstract

The letter by Z.F. Udwadia and coworkers reports interesting data on the Indian experience in the treatment of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) with linezolid. The European Respiratory Journal has recently become a forum for discussing potentialities of this drug in the treatment of MDR-/XDR-TB cases by publishing the TBNET (Tuberculosis Network European Trials group) study on 85 cases performed in four European countries (including Belarus in Eastern Europe), the Indian experience presented by Z.F. Udwadia and co-workers from Mumbai, India of 18 cases, and the two case reports of YEW et al. regarding the use of linezolid 800 mg q.d. The aim of the present study is to discuss the key findings of the TBNET and Indian studies and to draw further conclusions, focusing on the available evidence on linezolid safety
2010
http://erj.ersjournals.com/content/35/4/938.full.pdf+html?sid=77b77af3-7ab5-4cc0-8349-900757297d65
MULTIDRUG-RESISTANT TUBERCULOSIS, TOLERABILITY, TBNET
G., Sotgiu; R., Centis; C., Lange; L., D'Ambrosio; G., Guenther; Spanevello, Antonio; G. B., Migliori
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11383/1826920
 Attenzione

L'Ateneo sottopone a validazione solo i file PDF allegati

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 0
  • ???jsp.display-item.citation.isi??? 2
social impact