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EnglishThe aim of this study was to assess the immunomodulatory effect of KC-1317 (a symbiotic mixture containing Saccharomyces boulardii lysate in a cranberry, colostrum-derived lactoferrin, fragaria, and lactose mixture) supplementation in immune-compromised but otherwise healthy elderly subjects. A liquid formulation of KC-1317 was administered in a randomized controlled trial (RCT) fashion to healthy volunteers (65-79 years) previously selected for low natural killer (NK) cell activity, and this parameter was checked at the completion of the study. A significant improvement in NK cell activity of KC-1317 consumers was observed as compared to placebo at the end of 2 months. Although preliminary, these beneficial immune-modulatory effects of KC-1317 in aged individuals might indicate its employment within a wider age-management strategy.
| Autori: | |
| Data di pubblicazione: | 2014 |
| Titolo: | Gut-targeted immunonutrition boosting natural killer cell activity using Saccharomyces boulardii lysates in immuno-compromised healthy elderly subjects. |
| Rivista: | REJUVENATION RESEARCH |
| Digital Object Identifier (DOI): | 10.1089/rej.2013.1500 |
| Codice identificativo ISI: | WOS:000334543600017 |
| Codice identificativo Scopus: | 2-s2.0-84898932063 |
| Codice identificativo Pubmed: | 24059806 |
| Parole Chiave: | immunomodulating agent; kc 1317; placebo; probiotic agent; unclassified drug; immunologic factor |
| Appare nelle tipologie: | Articolo su Rivista |
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