Findings of this study provide evidence that the increased susceptibility to somatic mutagenesis exhibited by the JAK2 GGCC haplotype is not restricted to JAK2-V617F, but also includes the less frequent but more diverse JAK2 exon 12 mutations.

The 'GGCC' haplotype of JAK2 confers susceptibility to JAK2 exon 12 mutation-positive polycythemia vera.

PASSAMONTI, FRANCESCO;
2009-01-01

Abstract

Findings of this study provide evidence that the increased susceptibility to somatic mutagenesis exhibited by the JAK2 GGCC haplotype is not restricted to JAK2-V617F, but also includes the less frequent but more diverse JAK2 exon 12 mutations.
2009
http://www.nature.com/leu/journal/vaop/ncurrent/abs/leu2009110a.html
Myeloproliferative neoplasms; JAK2; mutagenesis
Olcaydu, D; Skoda, Rc; Looser, R; Li, S; Cazzola, M; Pietra, D; Passamonti, Francesco; Lippert, E; Carillo, S; Girodon, F; Vannucchi, A; Reading, Ns; ...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11383/2023351
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