Perimidines are extensively studied for their different therapeutic properties, including antiulcer, antifungal, antimicrobial, immunosuppressive and anticancer activities. Moreover, their heterocyclic structure embodies the naphthalene moiety, exploited in bio-imaging and biomolecules staining due to its high fluorescence. In this work we present the spectroscopic characterization of a family of perimidine derivatives, in order to obtain information potentially useful for the design of compounds combining biological activity and detectable fluorescence in physiological environment.

Fluorescence studies on 2-(het)aryl perimidine derivatives

LAMPERTI, MARCO;MASPERO, ANGELO;CIMINO, ALESSANDRO;PALMISANO, GIOVANNI;NARDO, LUCA
2016-01-01

Abstract

Perimidines are extensively studied for their different therapeutic properties, including antiulcer, antifungal, antimicrobial, immunosuppressive and anticancer activities. Moreover, their heterocyclic structure embodies the naphthalene moiety, exploited in bio-imaging and biomolecules staining due to its high fluorescence. In this work we present the spectroscopic characterization of a family of perimidine derivatives, in order to obtain information potentially useful for the design of compounds combining biological activity and detectable fluorescence in physiological environment.
Drug-DNA binding; Fluorescence; Perimidines; Theranostics; Biophysics; Biochemistry; Chemistry (all); Atomic and Molecular Physics, and Optics; Condensed Matter Physics
Giani, Arianna Maria; Lamperti, Marco; Maspero, Angelo; Cimino, Alessandro; Negri, Roberto; Giovenzana, Giovanni Battista; Palmisano, Giovanni; Nardo, Luca
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11383/2055069
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