The authors report two clinical trials concerning chemotherapy and immunotherapy combined in the treatment of primary and metastatic brain tumors. In the first study Bacillus Calmette-Guerin (BCG) and in the second levamisole (LMS) were utilized as immunostimulating agents. Chemotherapy was performed with BCNU and CCNU in association with surgery and/or radiotherapy. An immunological response was obtained but immunotherapy failed to demonstrate any significant effect on survival.
Chemotherapy plus immunotherapy for patients with primary and metastatic brain tumors
LOCATELLI, DAVIDE
1985-01-01
Abstract
The authors report two clinical trials concerning chemotherapy and immunotherapy combined in the treatment of primary and metastatic brain tumors. In the first study Bacillus Calmette-Guerin (BCG) and in the second levamisole (LMS) were utilized as immunostimulating agents. Chemotherapy was performed with BCNU and CCNU in association with surgery and/or radiotherapy. An immunological response was obtained but immunotherapy failed to demonstrate any significant effect on survival.
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