An ultrasound-assisted three-component, one-pot domino reaction with ferrocenecarboxaldehyde is herein reported. The sequence of reactions entails the allylindation and dehydrative alkylation of stabilized C-nucleophiles (e.g. electron-rich - (hetero)aromatics and stabilized enols) and N-nucleophiles (e.g. azoles). Sonochemical reactions have been performed in three different high-intensity reactors: a bath (20.3 kHz, 60 W), as well as two cup horns working at 19.9 kHz (75 W) and 300.5 kHz (70 W) giving a library of 18 new ferrocenyl derivatives.

One-pot sonochemical synthesis of ferrocenyl derivatives via a three-component reaction in aqueous media

PALMISANO, GIOVANNI;PENONI, ANDREA
2015-01-01

Abstract

An ultrasound-assisted three-component, one-pot domino reaction with ferrocenecarboxaldehyde is herein reported. The sequence of reactions entails the allylindation and dehydrative alkylation of stabilized C-nucleophiles (e.g. electron-rich - (hetero)aromatics and stabilized enols) and N-nucleophiles (e.g. azoles). Sonochemical reactions have been performed in three different high-intensity reactors: a bath (20.3 kHz, 60 W), as well as two cup horns working at 19.9 kHz (75 W) and 300.5 kHz (70 W) giving a library of 18 new ferrocenyl derivatives.
2015
www.elsevier.com/inca/publications/store/5/2/5/4/5/1
Allylation; Domino reaction; Ferrocene; Indium; Multi-component reaction; Ultrasound; Chemical Engineering (miscellaneous); Radiology, Nuclear Medicine and Imaging; Acoustics and Ultrasonics
Cappelletti, Luca; Vaghi, Luca; Rinaldi, Laura; Rotolo, Laura; Palmisano, Giovanni; Cravotto, Giancarlo; Penoni, Andrea
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11383/2063070
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