Patients with isolated functional or recurrent tricuspid regurgitation are often denied surgery because they are considered to be at high risk. Transcatheter valve therapy provides a less invasive alternative for tricuspid regurgitation associated with right heart failure. We have evaluated the feasibility of transcatheter tricuspid valve implantation of the NaviGate valved stent in a long-term swine model. The valved stent was successfully implanted through transjugular and transatrial approaches on the beating heart with excellent hemodynamic and valve performance. No conduction disturbance or coronary obstruction was observed. This technology could provide an alternative treatment for patients who are at high surgical risk with severe tricuspid regurgitation and compromised right ventricular function.

Transcatheter Tricuspid Valve Implantation of NaviGate Bioprosthesis in a Preclinical Model

Beghi, Cesare;
2018

Abstract

Patients with isolated functional or recurrent tricuspid regurgitation are often denied surgery because they are considered to be at high risk. Transcatheter valve therapy provides a less invasive alternative for tricuspid regurgitation associated with right heart failure. We have evaluated the feasibility of transcatheter tricuspid valve implantation of the NaviGate valved stent in a long-term swine model. The valved stent was successfully implanted through transjugular and transatrial approaches on the beating heart with excellent hemodynamic and valve performance. No conduction disturbance or coronary obstruction was observed. This technology could provide an alternative treatment for patients who are at high surgical risk with severe tricuspid regurgitation and compromised right ventricular function.
http://www.journals.elsevier.com/jacc-basic-to-translational-science
NaviGate bioprosthesis; preclinical model; transcatheter replacement; tricuspid valve; Cardiology and Cardiovascular Medicine
Navia, Jose L.; Kapadia, Samir; Elgharably, Haytham; Maluenda, Gabriel; Bartuś, Krzysztof; Baeza, Cristian; Nair, Rajesh K.; Rodés-Cabau, Josep; Beghi, Cesare; Quijano, Rodolfo C.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11383/2072463
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