Purpose – This paper aims to present the optimal design of an inductor used to heat a magnetic nanoparticle fluid injected in a cell culture inside a Petri dish. Design/methodology/approach – The inductor design is driven by means of a multi-objective optimization algorithm that generalizes the migration-non-dominated sorting genetic algorithm (NSGA); it is called self-adapting migration-NSGA. Findings – The optimized device is able to synthesize a uniform magnetic field in a nanoparticle fluid, substantially helping its heating capability. The ultimate scope is to assist the cancer therapy based on magnetic fluid hyperthermia (MFH). Originality/value – The optimal design of an inductor for MFH applications has been carried out by applying an improved version of migration-based NSGA-II algorithm including automatic stop and a self-adapting concept. The modified optimization algorithm is suitable to find better optimal solutions with respect to a standard version of NSGA-II.

Self-adaptive NGSA algorithm and optimal design of inductors for magneto-fluid hyperthermia

Forzan Michele;Sieni Elisabetta
2017-01-01

Abstract

Purpose – This paper aims to present the optimal design of an inductor used to heat a magnetic nanoparticle fluid injected in a cell culture inside a Petri dish. Design/methodology/approach – The inductor design is driven by means of a multi-objective optimization algorithm that generalizes the migration-non-dominated sorting genetic algorithm (NSGA); it is called self-adapting migration-NSGA. Findings – The optimized device is able to synthesize a uniform magnetic field in a nanoparticle fluid, substantially helping its heating capability. The ultimate scope is to assist the cancer therapy based on magnetic fluid hyperthermia (MFH). Originality/value – The optimal design of an inductor for MFH applications has been carried out by applying an improved version of migration-based NSGA-II algorithm including automatic stop and a self-adapting concept. The modified optimization algorithm is suitable to find better optimal solutions with respect to a standard version of NSGA-II.
2017
Magnetic fields; Optimal design; Multi-objective optimization; Finite element analysis; Genetic algorithms; Pareto optimization
Di Barba, Paolo; Dughiero, Fabrizio; Forzan, Michele; Sieni, Elisabetta
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11383/2077281
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