A novel, straightforward and high yielding synthesis of enantiomerically pure 2,6-disubstituted morpholines has been developed through the regioselective cyclization of diols. Cyclization precursors have been obtained by the ring opening of com. available chiral epoxides under solid-liq. phase transfer catalysis conditions (SL-PTC).

A practical approach to the synthesis of enantiomerically pure 2,6-disubstituted morpholines under phase transfer catalysis conditions

F. Foschi;
2009-01-01

Abstract

A novel, straightforward and high yielding synthesis of enantiomerically pure 2,6-disubstituted morpholines has been developed through the regioselective cyclization of diols. Cyclization precursors have been obtained by the ring opening of com. available chiral epoxides under solid-liq. phase transfer catalysis conditions (SL-PTC).
2009
Phase transfer catalysis; Cyclization; Sulfonamides; Morpholines
Albanese, D.; Foschi, F.; Penso, M.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11383/2086292
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