Many radiopharmaceuticals have been successfully used in nuclear medicine to detect neuroendocrine tumors, and many of them are based on a specific mechanism of uptake, while others are non-specific probes. This "review" focuses on the clinical applications of metaiodobenzylguanidine, (111)In-pentreotide and positron emission tomography (PET) tracers. New avances in diagnostic imaging will be discussed. Molecular imaging serves these diagnostic functions and provides powerful means for non-invasively detecting disease.

Radionuclide imaging of neurendocrine tumors: biological basis and diagnostic results

Genovese, Eugenio Annibale;
2013-01-01

Abstract

Many radiopharmaceuticals have been successfully used in nuclear medicine to detect neuroendocrine tumors, and many of them are based on a specific mechanism of uptake, while others are non-specific probes. This "review" focuses on the clinical applications of metaiodobenzylguanidine, (111)In-pentreotide and positron emission tomography (PET) tracers. New avances in diagnostic imaging will be discussed. Molecular imaging serves these diagnostic functions and provides powerful means for non-invasively detecting disease.
2013
3-Iodobenzylguanidine; Adrenal Gland Neoplasms; Biomarkers, Tumor; Carcinoma, Medullary; Gastrointestinal Neoplasms; Humans; Iodine Radioisotopes; Neuroendocrine Tumors; Pheochromocytoma; Positron-Emission Tomography; Receptors, Somatostatin; Sensitivity and Specificity; Somatostatin; Thyroid Neoplasms; Tomography, Emission-Computed, Single-Photon; Radiopharmaceuticals
Genovese, Eugenio Annibale; Mallardo, Vania; Rossi, Michele; Vaccaro, Andrea; Raucci, Antonio; Della Vecchi, Nicoletta; Romano, Giovanna; Califano, Teresa; Schillirò, Francesco
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11383/2094743
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