Preliminary studies suggested that drug-related toxicity of sunitinib may correlate with a better prognosis. We conducted a retrospective multicenter study regarding sunitinib-related toxicity. We evaluated 145 patients with metastatic renal cancer treated with sunitinib in first-line therapy. At univariate and multivariate analysis, we observed a protective effect of hypertension and neutropenia on tumor progression.

On-target Toxicities Predictive of Survival in Metastatic Renal Cell Carcinoma (mRCC) Treated With Sunitinib: A Multicenter Retrospective Study

Bolzacchini E.;Pinotti G.;Verusio C.;Mumoli N.;Rossini C.;Barzaghi S.;Ballerio A.;Dentali F.
2020-01-01

Abstract

Preliminary studies suggested that drug-related toxicity of sunitinib may correlate with a better prognosis. We conducted a retrospective multicenter study regarding sunitinib-related toxicity. We evaluated 145 patients with metastatic renal cancer treated with sunitinib in first-line therapy. At univariate and multivariate analysis, we observed a protective effect of hypertension and neutropenia on tumor progression.
2020
Hypertension; mRCC; Neutropenia; On target toxicities; Sunitinib
Bolzacchini, E.; Pinotti, G.; Bertu, L.; Verusio, C.; Galli, L.; Mumoli, N.; Barbara, C.; Danova, M.; Bregni, M.; Artale, S.; Rossini, C.; Nigro, O.; ...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11383/2097439
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