Extended-duration thromboprophylaxis with betrixaban reduces the risk of venous thromboembolism (VTE) without increasing major bleeding rates in acutely ill medical patients as compared to standard duration enoxaparin. We aimed to assess the risk-benefit of betrixaban in patients aged ≥ 80 years enrolled in the APEX trial.

Net-clinical benefit of extended prophylaxis of venous thromboembolism with betrixaban in medically ill patients aged 80 or more

Ageno, Walter
Primo
;
2019-01-01

Abstract

Extended-duration thromboprophylaxis with betrixaban reduces the risk of venous thromboembolism (VTE) without increasing major bleeding rates in acutely ill medical patients as compared to standard duration enoxaparin. We aimed to assess the risk-benefit of betrixaban in patients aged ≥ 80 years enrolled in the APEX trial.
2019
betrixaban; elderly; medical patients; prophylaxis; venous thromboembolism; Administration, Oral; Adult; Aged; Aged, 80 and over; Anticoagulants; Benzamides; Blood Coagulation; Double-Blind Method; Drug Administration Schedule; Enoxaparin; Factor Xa Inhibitors; Female; Hemorrhage; Humans; Male; Middle Aged; Progression-Free Survival; Pyridines; Risk Assessment; Risk Factors; Time Factors; Venous Thromboembolism
Ageno, Walter; Lopes, Renato D; Yee, Megan K; Hernandez, Adrian; Hull, Russell D; Goldhaber, Samuel Z; Gibson, C Michael; Cohen, Alexander T
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11383/2097989
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