Pulmonary embolism (PE) is a common and often fatal disease. In the US, an estimated 40-53 people per 100 000 are diagnosed with PE annually and approximately 60 000 die from the disease. Diagnosis is difficult because symptoms are non-specific; however, a quick and accurate diagnosis is critical because, with appropriate therapy, the risk of recurrent (and potentially fatal) PE can be greatly reduced. Recent publication of prediction rules and improved non-invasive diagnostic tools have simplified diagnostic algorithms for PE. The efficacy of the standard treatment for PE, initial administration of continuous i.v. unfractionated heparin overlapped with long-term oral anticoagulation, is well established. However, newer treatment options such as low-molecular-weight heparins and the pentasaccharides may offer similar efficacy with improved convenience. © 2005 Blackwell Publishing Ltd.

Update on the diagnosis and management of pulmonary embolism

Ageno W.;
2005-01-01

Abstract

Pulmonary embolism (PE) is a common and often fatal disease. In the US, an estimated 40-53 people per 100 000 are diagnosed with PE annually and approximately 60 000 die from the disease. Diagnosis is difficult because symptoms are non-specific; however, a quick and accurate diagnosis is critical because, with appropriate therapy, the risk of recurrent (and potentially fatal) PE can be greatly reduced. Recent publication of prediction rules and improved non-invasive diagnostic tools have simplified diagnostic algorithms for PE. The efficacy of the standard treatment for PE, initial administration of continuous i.v. unfractionated heparin overlapped with long-term oral anticoagulation, is well established. However, newer treatment options such as low-molecular-weight heparins and the pentasaccharides may offer similar efficacy with improved convenience. © 2005 Blackwell Publishing Ltd.
Diagnosis; Pulmonary embolism; Treatment; Venous thromboembolism
Garcia, D.; Ageno, W.; Libby, E.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11383/2098289
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