The Delta variant of concern of severe acute respiratory syndrome coronavirus 2 is dominant worldwide. We report a case cluster caused by Delta sublineage B.1.617.2 harboring the mutation E484K in Italy during July 11-July 29, 2021. This mutation appears to affect immune response and vaccine efficacy; monitoring its appearance is urgent.

Breakthrough Infections of E484K-Harboring SARS-CoV-2 Delta Variant, Lombardy, Italy

Baj, Andreina
Primo
;
Novazzi, Federica
Secondo
;
Genoni, Angelo;Maggi, Fabrizio
Ultimo
2021-01-01

Abstract

The Delta variant of concern of severe acute respiratory syndrome coronavirus 2 is dominant worldwide. We report a case cluster caused by Delta sublineage B.1.617.2 harboring the mutation E484K in Italy during July 11-July 29, 2021. This mutation appears to affect immune response and vaccine efficacy; monitoring its appearance is urgent.
B.1.617.2; COVID-19; E484K; Italy; SARS-CoV-2; coronavirus disease; delta variant; mutation of concern; respiratory infections; severe acute respiratory syndrome coronavirus 2; variant of concern; viruses; zoonoses
Baj, Andreina; Novazzi, Federica; Pasciuta, Renee; Genoni, Angelo; Ferrante, Francesca Drago; Valli, Marilena; Partenope, Michele; Tripiciano, Rosalia; Ciserchia, Andrea; Catanoso, Giuseppe; Focosi, Daniele; Maggi, Fabrizio
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11383/2115465
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