Common neurodegenerative disorders have been long-hypothesized to be linked with blood platelet biology. Genomic approaches have been recently used to unravel a possibly shared genetic basis between neurodegenerative risk and platelet parameters. A significant though moderate genetic correlation between Parkinson Disease (PD) risk and an index of platelet size variability, has been reported.
Genomic overlap between age at onset of Parkinson Disease and blood platelet parameters variability
Licia Iacoviello;Alessandro Gialluisi
2021-01-01
Abstract
Common neurodegenerative disorders have been long-hypothesized to be linked with blood platelet biology. Genomic approaches have been recently used to unravel a possibly shared genetic basis between neurodegenerative risk and platelet parameters. A significant though moderate genetic correlation between Parkinson Disease (PD) risk and an index of platelet size variability, has been reported.
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