Patients infected by SARS-CoV-2 can develop interstitial pneumonia, requiring hospitalisation or mechanical ventilation. Increased levels of inflammatory biomarkers are associated with development of acute respiratory distress syndrome (ARDS). The aim of the present study was to determine which cytokines are associated with respiratory insufficiency in patients hospitalised for COVID-19.

Interleukin 6, soluble interleukin 2 receptor alpha (CD25), monocyte colony-stimulating factor, and hepatocyte growth factor linked with systemic hyperinflammation, innate immunity hyperactivation, and organ damage in COVID-19 pneumonia

Peghin, Maddalena;
2021

Abstract

Patients infected by SARS-CoV-2 can develop interstitial pneumonia, requiring hospitalisation or mechanical ventilation. Increased levels of inflammatory biomarkers are associated with development of acute respiratory distress syndrome (ARDS). The aim of the present study was to determine which cytokines are associated with respiratory insufficiency in patients hospitalised for COVID-19.
COVID-19; Coronavirus; Hepatocyte growth factor; Interleukin 2; Interleukin 6; M-CSF; Pneumonia; Aged; COVID-19; Cytokines; Female; Hepatocyte Growth Factor; Host-Pathogen Interactions; Humans; Immunity, Innate; Inflammation; Interleukin-2 Receptor alpha Subunit; Interleukin-6; Macrophage Colony-Stimulating Factor; Male; Middle Aged; Multiple Organ Failure; Pneumonia; Retrospective Studies; SARS-CoV-2
Quartuccio, Luca; Fabris, Martina; Sonaglia, Arianna; Peghin, Maddalena; Domenis, Rossana; Cifù, Adriana; Curcio, Francesco; Tascini, Carlo
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11383/2140688
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