The broad family of viruses known as anelloviruses (AV) infects both humans and numerous animal species. They have a tiny, covalently closed single-stranded DNA genome and the astonishing capacity to infect a very high percentage of healthy and ill people with chronic infections that could last a lifetime. AV, and particularly the prototype Torquetenovirus, have established a successful interaction with the host's immune system and the rate at which they replicate is a gauge to measure overall immune function, even though many aspects of their life cycle and pathogenesis are still poorly understood.

TTV and other anelloviruses: The astonishingly wide spread of a viral infection

Baj, Andreina;Novazzi, Federica;Ferrante, Francesca Drago;Maggi, Fabrizio
2023-01-01

Abstract

The broad family of viruses known as anelloviruses (AV) infects both humans and numerous animal species. They have a tiny, covalently closed single-stranded DNA genome and the astonishing capacity to infect a very high percentage of healthy and ill people with chronic infections that could last a lifetime. AV, and particularly the prototype Torquetenovirus, have established a successful interaction with the host's immune system and the rate at which they replicate is a gauge to measure overall immune function, even though many aspects of their life cycle and pathogenesis are still poorly understood.
2023
2023
Anellovirus; Immune system; TTMDV; TTMV; TTV; Virome.
Spezia, Pietro Giorgio; Focosi, Daniele; Baj, Andreina; Novazzi, Federica; Ferrante, Francesca Drago; Carletti, Fabrizio; Minosse, Claudia; Matusali, ...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11383/2149651
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