Background: Influenza vaccination protects high-risk populations from severe outcomes.Methods: During the 2011-2012 flu season at "Gemelli Hospital" in Rome, all hospitalised patients who developed suspected influenza-like illness within 14 days were recruited to assess the feasibility of testing the influenza vaccine effectiveness against laboratory-confirmed influenza requiring hospitalisation.Conclusions: No difference in vaccine status between patients with positive and negative laboratory tests was found due to the small sample size. Larger numbers are required to explore influenza vaccine effectiveness.Results: Sixty-two patients were recruited; among them, 18 were laboratory confirmed for influenza A or B. In the target group for vaccination (N=47), the prevalence of vaccinated subjects was less than expected (38%).

Assessment of seasonal influenza vaccine effectiveness in patients from a central Italy reference hospital: Pitfalls and intricacies from a pilot case-control study

Iacoviello, L.
2014-01-01

Abstract

Background: Influenza vaccination protects high-risk populations from severe outcomes.Methods: During the 2011-2012 flu season at "Gemelli Hospital" in Rome, all hospitalised patients who developed suspected influenza-like illness within 14 days were recruited to assess the feasibility of testing the influenza vaccine effectiveness against laboratory-confirmed influenza requiring hospitalisation.Conclusions: No difference in vaccine status between patients with positive and negative laboratory tests was found due to the small sample size. Larger numbers are required to explore influenza vaccine effectiveness.Results: Sixty-two patients were recruited; among them, 18 were laboratory confirmed for influenza A or B. In the target group for vaccination (N=47), the prevalence of vaccinated subjects was less than expected (38%).
2014
Hospitalisation; Influenza vaccine effectiveness; Influenza-like illness; Pilot case-control study
Costanzo, S.; de Katleen, G. D.; Campana, L.; Olivieri, M.; Santangelo, R.; Sanguinetti, M.; Cauda, R.; Iacoviello, L.
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11383/2150872
 Attenzione

L'Ateneo sottopone a validazione solo i file PDF allegati

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 1
  • ???jsp.display-item.citation.isi??? ND
social impact