Pretreatment with intracerebroventricular pertussis toxin six days before, abolished analgesia induced by central morphine in the hot plate test. In contrast the toxin did not affect analgesia evoked by neurotensin and ASU 1-7 Eel calcitonin. The role of G proteins in opioid and non-opioid analgesia is discussed.

Effect of pertussis toxin on opioid and non-opioid induced analgesia

Parolaro D.;Rubino T.;
1990-01-01

Abstract

Pretreatment with intracerebroventricular pertussis toxin six days before, abolished analgesia induced by central morphine in the hot plate test. In contrast the toxin did not affect analgesia evoked by neurotensin and ASU 1-7 Eel calcitonin. The role of G proteins in opioid and non-opioid analgesia is discussed.
1990
AA.VV.
New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914
044481213X
The International Narcotics Research Conference
-
8 July 1989 through 13 July 1989
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11383/2153558
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