IntroductionA strong and well-known association exists between salt consumption, potassium intake, and cardiovascular diseases. MINISAL-SIIA results showed high salt and low potassium consumption in Italian hypertensive patients. In addition, a recent Italian survey showed that the degree of knowledge and behaviour about salt was directly interrelated, suggesting a key role of the educational approach.AimThe present multicentre randomised controlled trial study aimed to evaluate the efficacy of a short-time dietary educational intervention by a physician, only during the first visit, on sodium and potassium intake in hypertensive patients.MethodsTwo-hundred-thirty hypertensive subjects participating in the MINISAL-SIIA study were enrolled for this study. After the randomisation, the participants were stratified into the educational intervention (EI) group (n = 109) and control group (C) (n = 121). Anthropometric indexes and blood pressure (BP) measurements were taken in the single-centre, and 24-hour urinary sodium (UrNa) and potassium (UrK) excretion were centrally measured.ResultsAfter 3 months, there was a reduction in BP, UrNa, and body weight, and an increase in UrK in EI. By contrast, a lower decrease in BP was found in the C group, and a slight rise in UrNa and no substantial change in UrK were revealed. BP changes were positively and significantly associated with changes in UrNa only in EI.ConclusionThe main results of this trial indicate that a single brief educational intervention by a physician can lead to a reduction in salt intake and BP, and increased potassium consumption in hypertensive patients, without adverse effects.Trail registration: ClinicalTrial.gov registration number: NCT06651437.ConclusionThe main results of this trial indicate that a single brief educational intervention by a physician can lead to a reduction in salt intake and BP, and increased potassium consumption in hypertensive patients, without adverse effects.Trail registration: ClinicalTrial.gov registration number: NCT06651437.Graphical AbstractThe main findings of this randomised controlled trial on hypertensive patients indicate that a short-time dietary educational intervention during the baseline visit is associated with slight improvements in salt and potassium intake and a reduction in blood pressure after three months. These results highlight the importance of providing adequate dietary counselling during the patient's visits to help reduce cardiovascular risk in patients with hypertension.

“Minimal-Advice” on Salt Intake: Results of a Multicentre Pilot Randomised Controlled Trial on Hypertensive Patients

Maresca A.;
2025-01-01

Abstract

IntroductionA strong and well-known association exists between salt consumption, potassium intake, and cardiovascular diseases. MINISAL-SIIA results showed high salt and low potassium consumption in Italian hypertensive patients. In addition, a recent Italian survey showed that the degree of knowledge and behaviour about salt was directly interrelated, suggesting a key role of the educational approach.AimThe present multicentre randomised controlled trial study aimed to evaluate the efficacy of a short-time dietary educational intervention by a physician, only during the first visit, on sodium and potassium intake in hypertensive patients.MethodsTwo-hundred-thirty hypertensive subjects participating in the MINISAL-SIIA study were enrolled for this study. After the randomisation, the participants were stratified into the educational intervention (EI) group (n = 109) and control group (C) (n = 121). Anthropometric indexes and blood pressure (BP) measurements were taken in the single-centre, and 24-hour urinary sodium (UrNa) and potassium (UrK) excretion were centrally measured.ResultsAfter 3 months, there was a reduction in BP, UrNa, and body weight, and an increase in UrK in EI. By contrast, a lower decrease in BP was found in the C group, and a slight rise in UrNa and no substantial change in UrK were revealed. BP changes were positively and significantly associated with changes in UrNa only in EI.ConclusionThe main results of this trial indicate that a single brief educational intervention by a physician can lead to a reduction in salt intake and BP, and increased potassium consumption in hypertensive patients, without adverse effects.Trail registration: ClinicalTrial.gov registration number: NCT06651437.ConclusionThe main results of this trial indicate that a single brief educational intervention by a physician can lead to a reduction in salt intake and BP, and increased potassium consumption in hypertensive patients, without adverse effects.Trail registration: ClinicalTrial.gov registration number: NCT06651437.Graphical AbstractThe main findings of this randomised controlled trial on hypertensive patients indicate that a short-time dietary educational intervention during the baseline visit is associated with slight improvements in salt and potassium intake and a reduction in blood pressure after three months. These results highlight the importance of providing adequate dietary counselling during the patient's visits to help reduce cardiovascular risk in patients with hypertension.
2025
2025
Salt; Sodium; Salt Awareness; Salt Behaviour; Potassium; Dietary Questionnaire; Hypertension; Urinary Sodium; Urinary Potassium
D'Elia, L.; Strazzullo, P.; Del Giudice, A.; Desideri, G.; Di Quattro, R.; Ferri, C.; Grossi, A.; Malatino, L.; Mallamaci, F.; Maresca, A.; Meschi, M....espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11383/2189852
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