Italian Melanoma Intergroup tele-genetic counseling project for melanoma predisposition syndromes: five-year evaluation of effectiveness and outcomes

: This study assessed the implementation of a tele-genetic counseling (TGC) pathway for hereditary melanoma risk using the culturally adapted Italian Melanoma Intergroup Tele-Genomics Outcome Scale (IMI-TGOS) questionnaire. Among 278 eligible patients, 177 (64%) completed the survey across three Italian centers. Responses showed high comprehension and perceived utility: 88% of participants reported understanding the information received, 96% recognized familial implications, and over 85% felt confident in managing risk and making decisions. While emotional responses were more varied, most respondents expressed confidence in future planning. These findings confirm the feasibility, acceptability, and informativeness of the IMI-TGOS in a remote counseling setting. The study supports the comparability of tele-genetic and in-person counseling in terms of understanding, retention, and decision-making. Moreover, the IMI-TGOS emerged as a promising tool for evaluating real-world genetic services. Broader adoption may help monitor outcomes and improve quality and equity in the expanding landscape of digital genetic care.