In July–18 August 2025, 171 autochthonous cases with West Nile virus (WNV) infection were confirmed in Lazio, Italy: four asymptomatic blood donors, 110 with WNV fever, 57 with neuroinvasive syndrome and nine deaths. WNV lineage 2 was detected in two neuroinvasive cases. Infection with WNV was confirmed in 28 horses, five crows and a Culex pipiens pool. We present the preliminary epidemiological and phylogenetic analysis of the outbreak and the public health measures taken within a One Health approach.
Outbreak of autochthonous West Nile virus infection in Lazio region, Italy, July to August 2025: preliminary investigation
Maggi F.;
2025-01-01
Abstract
In July–18 August 2025, 171 autochthonous cases with West Nile virus (WNV) infection were confirmed in Lazio, Italy: four asymptomatic blood donors, 110 with WNV fever, 57 with neuroinvasive syndrome and nine deaths. WNV lineage 2 was detected in two neuroinvasive cases. Infection with WNV was confirmed in 28 horses, five crows and a Culex pipiens pool. We present the preliminary epidemiological and phylogenetic analysis of the outbreak and the public health measures taken within a One Health approach.
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