A new synthesis of quinoline derivatives was achieved by catalytic hydrogenation of 3,4-disubstituted 2-(2-formylphenyl)-isoxazolin-5(2H)-ones. In the same way, 2,3-disubstituted [1,8]naphthyridine was obtained.
A valuable heterocyclic ring transformation: from isoxazolin-5(2H)-ones to quinolines
BROGGINI, GIANLUIGI;
2003-01-01
Abstract
A new synthesis of quinoline derivatives was achieved by catalytic hydrogenation of 3,4-disubstituted 2-(2-formylphenyl)-isoxazolin-5(2H)-ones. In the same way, 2,3-disubstituted [1,8]naphthyridine was obtained.
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Tetrahedron 2003 p.9887 (63).pdf
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