Purpose. To present a computer-Assisted-design/computer-Assisted-manufacturing (CAD/CAM) technique for the design, fabrication, and clinical application of custom-made synthetic scaffolds, for alveolar ridge augmentation. Methods.The CAD/CAM procedure consisted of (1) virtual planning/design of the custom-made scaffold; (2) milling of the scaffold into the exact size/shape from a preformed synthetic bone block; (3) reconstructive surgery. The main clinical/radiographic outcomes were vertical/horizontal bone gain, any biological complication, and implant survival. Results. Fifteen patients were selected who had been treated with a custom-made synthetic scaffold for ridge augmentation. The scaffolds closely matched the shape of the defects: This reduced the operation time and contributed to good healing. A few patients experienced biological complications, such as pain/swelling (2/15: 13.3%) and exposure of the scaffold (3/15: 20.0%); one of these had infection and complete graft loss. In all other patients, 8 months after reconstruction, a well-integrated newly formed bone was clinically available, and the radiographic evaluation revealed amean vertical and horizontal bone gain of 2.1?0.9mmand 3.0?1.0 mm, respectively. Fourteen implants were placed and restored with single crowns.The implant survival rate was 100%. Conclusions. Although positive outcomes have been found with custom-made synthetic scaffolds in alveolar ridge augmentation, further studies are needed to validate this technique.

Custom-made synthetic scaffolds for bone reconstruction: A retrospective, multicenter clinical study on 15 patients

Mangano, Francesco Guido;Macchi, Aldo;Mangano, Carlo
2016

Abstract

Purpose. To present a computer-Assisted-design/computer-Assisted-manufacturing (CAD/CAM) technique for the design, fabrication, and clinical application of custom-made synthetic scaffolds, for alveolar ridge augmentation. Methods.The CAD/CAM procedure consisted of (1) virtual planning/design of the custom-made scaffold; (2) milling of the scaffold into the exact size/shape from a preformed synthetic bone block; (3) reconstructive surgery. The main clinical/radiographic outcomes were vertical/horizontal bone gain, any biological complication, and implant survival. Results. Fifteen patients were selected who had been treated with a custom-made synthetic scaffold for ridge augmentation. The scaffolds closely matched the shape of the defects: This reduced the operation time and contributed to good healing. A few patients experienced biological complications, such as pain/swelling (2/15: 13.3%) and exposure of the scaffold (3/15: 20.0%); one of these had infection and complete graft loss. In all other patients, 8 months after reconstruction, a well-integrated newly formed bone was clinically available, and the radiographic evaluation revealed amean vertical and horizontal bone gain of 2.1?0.9mmand 3.0?1.0 mm, respectively. Fourteen implants were placed and restored with single crowns.The implant survival rate was 100%. Conclusions. Although positive outcomes have been found with custom-made synthetic scaffolds in alveolar ridge augmentation, further studies are needed to validate this technique.
http://www.hindawi.com/journals/biomed/
Alveolar Process; Alveolar Ridge Augmentation; Bone Transplantation; Bone and Bones; Computer-Aided Design; Dental Implants; Female; Humans; Jaw, Edentulous, Partially; Male; Middle Aged; Pain; Reconstructive Surgical Procedures; Retrospective Studies; Tissue Scaffolds; Treatment Outcome; Biochemistry, Genetics and Molecular Biology (all); Immunology and Microbiology (all)
Luongo, Fabrizia; Mangano, Francesco Guido; Macchi, Aldo; Luongo, Giuseppe; Mangano, Carlo
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11383/2072432
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