This review reports the achievements in copper(II) triflate-catalyzed processes concerning the multicomponent reactions, applied to the synthesis of acyclic and cyclic compounds. In particular, for the heteropolycyclic systems mechanistic insights were outlined as well as cycloaddition and aza-Diels–Alder reactions were included. These strategies have gained attention due to their highly atom- and step-economy, one-step multi-bond forming, mild reaction conditions, low cost and easy handling.

Cu(OTf)2-catalyzed multicomponent reactions

Colombo, Sara;Loro, Camilla;Broggini, Gianluigi;Papis, Marta
2025-01-01

Abstract

This review reports the achievements in copper(II) triflate-catalyzed processes concerning the multicomponent reactions, applied to the synthesis of acyclic and cyclic compounds. In particular, for the heteropolycyclic systems mechanistic insights were outlined as well as cycloaddition and aza-Diels–Alder reactions were included. These strategies have gained attention due to their highly atom- and step-economy, one-step multi-bond forming, mild reaction conditions, low cost and easy handling.
2025
2025
cascade process; copper catalysis; heteropolycycles; multicomponent reactions; one-pot reaction
Colombo, Sara; Loro, Camilla; Beccalli, Egle M; Broggini, Gianluigi; Papis, Marta
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11383/2190372
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