TOSI, GIOVANNA
 Distribuzione geografica
Continente #
NA - Nord America 9.940
EU - Europa 8.501
AS - Asia 4.081
SA - Sud America 461
AF - Africa 50
Continente sconosciuto - Info sul continente non disponibili 8
OC - Oceania 4
Totale 23.045
Nazione #
US - Stati Uniti d'America 9.761
IT - Italia 4.320
UA - Ucraina 1.555
SG - Singapore 1.346
CN - Cina 718
VN - Vietnam 674
TR - Turchia 648
DE - Germania 580
SE - Svezia 576
HK - Hong Kong 510
FI - Finlandia 428
BR - Brasile 414
IE - Irlanda 298
RU - Federazione Russa 242
GB - Regno Unito 221
FR - Francia 134
CA - Canada 122
IN - India 50
MX - Messico 46
PL - Polonia 38
JP - Giappone 36
BE - Belgio 32
ZA - Sudafrica 24
ES - Italia 21
AR - Argentina 18
BD - Bangladesh 17
NL - Olanda 15
IQ - Iraq 13
KR - Corea 11
PK - Pakistan 10
LT - Lituania 9
MA - Marocco 9
AE - Emirati Arabi Uniti 8
EU - Europa 8
CH - Svizzera 7
EC - Ecuador 7
IR - Iran 7
CZ - Repubblica Ceca 6
VE - Venezuela 6
ID - Indonesia 5
SA - Arabia Saudita 5
UZ - Uzbekistan 5
CO - Colombia 4
KE - Kenya 4
LB - Libano 4
PY - Paraguay 4
TN - Tunisia 4
TW - Taiwan 4
AT - Austria 3
BY - Bielorussia 3
DZ - Algeria 3
JM - Giamaica 3
PE - Perù 3
RS - Serbia 3
AU - Australia 2
BH - Bahrain 2
CI - Costa d'Avorio 2
CL - Cile 2
GR - Grecia 2
HR - Croazia 2
IL - Israele 2
MT - Malta 2
NZ - Nuova Zelanda 2
TT - Trinidad e Tobago 2
UY - Uruguay 2
AO - Angola 1
BB - Barbados 1
CR - Costa Rica 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
EG - Egitto 1
GA - Gabon 1
GY - Guiana 1
HN - Honduras 1
KH - Cambogia 1
KW - Kuwait 1
KZ - Kazakistan 1
ME - Montenegro 1
MK - Macedonia 1
NO - Norvegia 1
PA - Panama 1
PH - Filippine 1
PR - Porto Rico 1
PS - Palestinian Territory 1
QA - Qatar 1
TG - Togo 1
Totale 23.045
Città #
Milan 3.337
Jacksonville 1.193
Fairfield 928
Chandler 783
Ashburn 724
Singapore 698
Woodbridge 609
Hong Kong 509
Wilmington 429
Ann Arbor 424
Houston 407
Izmir 406
Princeton 398
Seattle 389
Dearborn 366
Beijing 328
Nyköping 297
Dublin 296
Cambridge 287
Dallas 284
Dong Ket 268
Boardman 235
Rome 231
San Mateo 138
The Dalles 121
New York 112
Los Angeles 93
Como 91
Toronto 85
San Diego 76
Ogden 69
Munich 53
Santa Clara 50
São Paulo 50
Düsseldorf 45
Chicago 43
Helsinki 35
Tokyo 35
Hefei 34
Verona 33
Ho Chi Minh City 32
Warsaw 32
Brussels 31
London 29
Nanjing 28
Hanoi 27
Mexico City 26
Norwalk 25
Council Bluffs 23
Guangzhou 22
Turku 22
Boston 21
Frankfurt am Main 20
Phoenix 20
Pune 20
Kunming 19
Orem 19
Brooklyn 17
Falls Church 17
Johannesburg 17
Manchester 17
Jinan 16
Stockholm 16
Washington 16
St Petersburg 15
Columbus 14
Denver 14
Montreal 14
Chennai 13
Fuzhou 13
San Francisco 13
Belo Horizonte 11
Poplar 10
Amsterdam 9
Kocaeli 9
Atlanta 8
Brasília 8
Buffalo 8
Curitiba 8
Hangzhou 8
Kilburn 8
Nanchang 8
Nuremberg 8
Porto Alegre 8
Rio de Janeiro 8
Shanghai 8
Changsha 7
Hebei 7
Querétaro 7
Raleigh 7
Salt Lake City 7
Tehran 7
Xian 7
Auburn Hills 6
Chongqing 6
Guarulhos 6
Shenyang 6
Wuhan 6
Zhengzhou 6
Charlotte 5
Totale 15.834
Nome #
CIITA-driven MHC class ii expressing tumor cells can efficiently prime naive CD4+ TH cells in vivo and vaccinate the host against parental MHC-II-negative tumor cells 237
Boosting the MHC class II-restricted tumor antigen presentation to CD4+ T helper cells: A critical issue for triggering protective immunity and re-orienting the tumor microenvironment toward an anti-tumor state 225
Cytoplasmic Localization of HTLV-1 HBZ Protein: A Biomarker of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) 225
Active suppression of the class II transactivator-encoding AIR-1 locus is responsible for the lack of major histocompatibility complex class II gene expression observed during differentiation from B cells to plasma cells 202
Tripartite Motif-Containing Protein 22 Interacts with Class II Transactivator and Orchestrates Its Recruitment in Nuclear Bodies Containing TRIM19/PML and Cyclin T1 199
A girl with Diabetes and severe Combined Immunodeficiency from Adenosine Deaminase Deficiency 194
Cell lineage-specific and developmental stage-specific controls of MHC class-II-antigen expression. 193
Localization, quantification and interaction with host factors of endogenous HTLV-1 HBZ protein in infected cells and ATL 192
The MHC-II transactivator CIITA inhibits Tax-1-mediated HTLV-1 expression and NF-kB activation 187
CIITA-induced MHC class II expression in mammary adenocarcinoma leads to a Th1 polarization of the tumor microenvironment, tumor rejection, and specific anti-tumor memory 184
The MHC-II transactivator CIITA inhibits Tat function and HIV-1 replication in human myeloid cells 184
The MHC class II transactivator: prey and hunter in infectious diseases 182
CIITA-induced MHC class II expression in mammary adenocarcinoma leads to a Th1 polarization of the tumor microenvironment, tumor rejection and specific anti-tumor memory. 180
Adequate Antigen Availability: A Key Issue for Novel Approaches to Tumor Vaccination and Tumor Immunotherapy 176
Picosecond-resolved FRET on non-amplified DNA for identifying individuals genetically susceptible to type-1 diabetes 175
The MHC Class II transactivator CIITA inhibits the persistent activation of NF-kB by Tax-1 174
Typing of a polymorphic human gene conferring susceptibility to insulin-dependent diabetes mellitus by picosecond-resolved FRET on non-purified/non-amplified genomic DNA 172
The MHC-II transactivator CIITA, a restriction factor against oncogenic HTLV-1 and HTLV-2 retroviruses: similarities and differences in the inhibition of Tax-1 and Tax-2 viral transactivators 172
Autoimmunità e Malattie Autoimmuni 172
Localization, quantization and interaction with host factors of endogenous HTLV-1 HBZ protein in infected cells and ATL 168
CIITA-induced MHC class II expression in mammary adenocarcinoma leads to a TH1 polarization of the tumor microenvironment, tumor rejection, and specific antitumor memory 166
Proteomic analysis of dopamine and α-synuclein interplay in a cellular model of Parkinson's disease pathogenesis 165
The MHC class II transactivator CIITA inhibits Tax-1-mediated HTLV-1 expression and NF-kB activation. 163
The HLA class II transcriptional activator blocks the function of HIV-1 Tat and inhibits viral replication 162
Molecular and cellular correlates of the CIITA-mediated inhibition of HTLV-2 Tax-2 transactivator function resulting in loss of viral replication 160
Assessment of the DQB1-DQA1 complete genotype allows best prediction for IDDM 160
The MHC-II transactivator CIITA inhibits Tax-1-mediated HTLV-1 expression and NF-kB activation 155
Adequate Antigen Availability (AAA) in antitumor immunity: Definition and consequences for novel strategies of tumor prevention and antitumor treatment 155
Tumor Immunology meets Immunology: Modified cancer cells as professional APC for priming naïve tumor-specific CD4+ T cells 155
Multi-omics discovery of exome-derived neoantigens in hepatocellular carcinoma 153
Insight into the molecular mechanism of CIITA-mediated inhibition of HIV-1 and HTLV transactivators 152
MHC class II gene regulation: some historical considerations on a still ontogenetic and phylogenetic puzzle 151
Neonatal Fc receptor is involved in the protection of fibrinogen after its intake in peripheral blood mononuclear cells 151
A dual defensive role of CIITA against retroviral infections 150
The MHC-II transactivator CIITA, a viral restriction factor inhibiting the replication of Human T cell Lymphotropic virus type 1. 150
HIV-1 Tat mutants in the cysteine-rich region down-regulate HLA class II expression in T lymphocytic and macrophage cell lines 150
Distinct regulation of HLA class II and class I cell surface expression in THP-1 macrophage cell line after bacterial phagocytosis 148
HLA-DQ genotype in early onset insulin dependent diabetes mellitus 147
Phosphorylation of CIITA directs its oligomerization, accumulation and increased activity on MHCII promoters 146
MHC class II enhanceosome: how is the class II transactivator recruited to DNA-bound activators? 146
Associazione tra genotipo HLA-DQ e suscettibilità al Diabete insulino-Dipendente 146
Block of Stat-1 activation in macrophages, undergoing bacterial phagocytosis causes CIITA reduced transcription and consequent impaired antigen presentation 145
Time-Resolved Förster Resonance Energy Transfer Analysis of Single-Nucleotide Polymorphisms: Towards Molecular Typing of Genes on Non-Purified and Non-PCR-Amplified DNA 145
Highly stable oligomerization forms of HIV-1 Tat detected by monoclonal antibodies and requirement of monomeric forms for the transactivating function on the HIV-1 LTR 143
Major histocompatibility complex class II transcriptional platform: assembly of nuclear factor Y and regulatory factor X (RFX) on DNA requires RFX5 dimers 143
MHC class II transactivator CIITA inhibits Tax-2-mediated HTLV-2 LTR transactivation and viral replication by binding to and affecting Tax-2 intracellular localization 143
The MHC-II transactivator CIITA inhibits Tat-mediated HIV-1 LTR transactivation and virus replication in human U937 monocytic cells 142
Fowlpoxvirus recombinants coding for the CIITA gene increase the expression of endogenous MHC-II and Fowlpox Gag/Pro and Env SIV transgenes 142
A new strategy of tumor vaccination based on mammary adenocarcinoma cells transduced with the MHC class II transactivator CIITA 140
New approaches of cancer vaccination and cancer immunotherapy based on the optimal stimulation of tumor-specific, MHC class II-restricted CD4+ T helper cells 140
CIITA dependent MHC class II IA expression in tumor cells triggers CD4 T cell protective and long lasting antitumor immunity 139
Analysis of a combined immunodeficiency patient with defect in MHCII expression (BLS) reveals the presence of several mutant isoforms of RFXANK mRNA 138
Molecular and Cellular Correlates of the CIITA-Mediated Inhibition of HTLV-2 Tax-2 Transactivator Function Resulting in Loss of Viral Replication. 137
The MHC class II transactivator CIITA inhibits the persistent activation of NF-kB by Human T cell Lymphotropic Virus type-1 Tax-1 oncoprotein 137
Analysis of microchimerism in thyroid autoimmune diseases 136
Role of the HLA-DQ genotype in IDDM susceptibility 135
Tax-1-mediated HTLV-1 replication and NF-kB activation is inhibited by the MHC-II transactivator CIITA 135
Apparente dissociazione tra fenotipo DR e genotipo MHC di classe II in IDDM 134
Tax-1-mediated NF-kB activation is inhibited by the MHC-II transactivator CIITA 134
The complex interplay of the DQB1 and DQA1 loci in the generation of the susceptible and protective phenotype for Insulin-Dependent Diabetes Mellitus 134
The MHC-II transactivator CIITA, a viral restriction factor inhibiting the replication of Human T cell Lymphotropic virus type 1 133
The Major Histocompatibility Complex Class II Transactivator CIITA Inhibits the Persistent Activation of NF-kappa B by the Human T Cell Lymphotropic Virus Type 1 Tax-1 Oncoprotein 133
Tat protein is an HIV-1 encoded SS-chemochine homolog that promotes migrationand upregulates CCR3 on human FceRI+ cells 129
Transient internalization and/or block of export to the cell surface of HLA Class II and CD1b molecules after bacterial phagocytosis 129
Distinct subcellular localization of HTLV-1 HBZ oncoprotein in the ATL leukemic and HAM/TSP patients. 129
Inhibition of Human T-Cell Leukemia virus type 2 (HTLV-2) replication by the suppressive action of CIITA and NF-Y 128
Expression of MHC class I and class II antigens in pancreatic adenocarcinomas 128
Molecular typing of polymorphic genes by time-resolved fluorescence resonance energy transfer 128
HLA-DQB1 typing of north east italian IDDM patients using amplified DNA, oligonucleotide probes and a rapid DNA-Enzyme Immunoassay (DEIA) 128
Transient internalization and/or block of export to the cell surface of HLA Class II and CD1B molecules after mycobacterial phagocytosis 128
The MHC-II transactivator CIITA is a viral restriction factor against HIV-1 replication 128
HTLV-2 Tax-2 transactivator increases the expression and the function of its inhibitor CIITA, the master regulator of HLA-II gene transcription 127
The MHC Class II transactivator, CIITA,is a viral restriction factor for human oncogenic retroviruses 124
CIITA blocks the function of HIV-1 Tat by competing for cyclin T1 and inhibits viral replication 124
Cellular and molecular aspects of immune response relevant to autoimmune diseases 124
Associazione tra HLA-DQB1 e diabete giovanile analizzata a livello molecolare per Southern e DEIA 123
Optimal MHC-II-restricted tumor antigen presentation to CD4+ T helper cells: the key issue for development of anti-tumor vaccines 123
The MHC-II transactivator CIITA, a viral restriction factor inhibiting the replication of Human T cell Lymphotropic Virus Type 1 123
CIITA reduced transcription as the cause of HLA class II down-modulation in human macrophages during bacterial phagocytosis 122
The constitutive activation of NF-kB by HTLV-1 Tax-1 oncoprotein is inhibited by the MHC class II transactivator CIITA 122
Host-retrovirus interaction: role of CIITA in the inhibition of HTLV-1 replication and oncogenic potential 121
Tumor treatment by TNF-alpha targeted to tumor vessels and melphalan induces strong adaptive immune response, protection from tumor growth and anti-tumor memory. 120
A new strategy of tumor vaccination based on tumor cells transduced with the MHC class II transactivator CIITA 119
The MHC class II transactivator, CIITA, blocks the transcriptional activity of both HTLV-2 Tax-2 and HTLV-1 Tax-1 118
The MHC class II transactivator (CIITA): a physiologic inhibitor of HIV1 and HTLV2 retroviral infections 117
HTLV2 influence on pathways regulating proliferation and death in B cell line BJAB 117
Therapy-induced antitumor vaccination by targeting TNFa to tumor vessels in combination with melphalan 116
Efficient antigen presentation and T cell activation by MHC class II molecules of CIITA-transfected epatocarcinoma cells 116
Human T-cell leukemia virus type II directly acts on CD34+ hematopoietic precursors by increasing their survival potential. Envelope associated HLA class II molecules reverse this effect 115
Control of mammary adenocarcinoma growth in vivo by gene therapy with the MHC class II transactivator CIITA 114
Regulation of HLA antigen expression in HIV infected cells 114
Evidence for a specific post- transcriptional mechanism controlling the expression of HLA-DQ, but not DR and DP molecules 113
TPA-mediated down-regulation of MHC class II gene expression in human macrophage precursors by destabilization of the MHC-II transactivator (CIITA) mRNA 113
CIITA, the Master Regulator of MHC Class II Gene Transcription, Targets the Viral Transactivator Tax-1 to Inhibit HTLV-I Viral Replication and NFKB Activation 112
The MHC class II transactivator (CIITA): a "physiologic" drug against HIV-1 replication 112
The MHC-II transactivator CIITA, a viral restriction factor inhibiting the replication of Human T cell Lymphotropic Virus Type 1 112
Approcci immunogenetici per il controllo dell'infezione da retrovirus umani 112
The molecular basis of the inhibition of HTLV-2 retroviral replication by the MHC class II transactivator (CIITA) 111
The MHC class II transactivator (CIITA): a physiologic inhibitor of HTLV-2 retroviral infection. 111
HTLV-II Tax-2 increases the cell surface expression of HLA-II molecules by acting at the level of CIITA, the master regulator of HLA-II transcription 110
Totale 14.492
Categoria #
all - tutte 91.633
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 91.633


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.949 0 0 0 0 0 272 83 287 431 102 242 532
2021/20221.700 211 223 152 133 42 48 57 123 83 222 159 247
2022/20232.159 252 86 120 258 159 493 0 292 312 63 69 55
2023/20244.884 816 801 919 824 877 310 50 40 155 20 9 63
2024/20252.562 10 45 483 50 107 108 123 141 313 158 220 804
2025/20262.571 492 363 187 862 539 128 0 0 0 0 0 0
Totale 23.111