TOSI, GIOVANNA
 Distribuzione geografica
Continente #
NA - Nord America 11.818
EU - Europa 8.817
AS - Asia 5.326
SA - Sud America 496
AF - Africa 67
Continente sconosciuto - Info sul continente non disponibili 8
OC - Oceania 6
Totale 26.538
Nazione #
US - Stati Uniti d'America 11.604
IT - Italia 4.341
SG - Singapore 1.676
UA - Ucraina 1.555
CN - Cina 1.220
VN - Vietnam 892
TR - Turchia 654
DE - Germania 589
SE - Svezia 577
HK - Hong Kong 565
FI - Finlandia 477
BR - Brasile 435
FR - Francia 315
IE - Irlanda 298
GB - Regno Unito 251
RU - Federazione Russa 243
CA - Canada 138
IN - India 100
MX - Messico 57
BD - Bangladesh 46
PL - Polonia 42
JP - Giappone 41
BE - Belgio 32
NL - Olanda 26
ZA - Sudafrica 26
ES - Italia 22
IQ - Iraq 20
AR - Argentina 19
PK - Pakistan 14
KR - Corea 12
LT - Lituania 11
MA - Marocco 11
AE - Emirati Arabi Uniti 10
EC - Ecuador 10
PH - Filippine 10
VE - Venezuela 9
EU - Europa 8
CH - Svizzera 7
IR - Iran 7
CZ - Repubblica Ceca 6
ID - Indonesia 6
KE - Kenya 6
MY - Malesia 6
NG - Nigeria 6
PE - Perù 6
PY - Paraguay 6
SA - Arabia Saudita 6
UZ - Uzbekistan 6
JO - Giordania 5
TN - Tunisia 5
TW - Taiwan 5
AT - Austria 4
CL - Cile 4
CO - Colombia 4
DZ - Algeria 4
JM - Giamaica 4
LB - Libano 4
MD - Moldavia 4
AU - Australia 3
BY - Bielorussia 3
EG - Egitto 3
IL - Israele 3
KH - Cambogia 3
NP - Nepal 3
PA - Panama 3
RS - Serbia 3
BH - Bahrain 2
CI - Costa d'Avorio 2
CR - Costa Rica 2
DO - Repubblica Dominicana 2
GA - Gabon 2
GR - Grecia 2
HN - Honduras 2
HR - Croazia 2
MT - Malta 2
NZ - Nuova Zelanda 2
PR - Porto Rico 2
PS - Palestinian Territory 2
TT - Trinidad e Tobago 2
UY - Uruguay 2
AO - Angola 1
AZ - Azerbaigian 1
BB - Barbados 1
BG - Bulgaria 1
DK - Danimarca 1
GE - Georgia 1
GY - Guiana 1
KW - Kuwait 1
KZ - Kazakistan 1
ME - Montenegro 1
MK - Macedonia 1
NO - Norvegia 1
OM - Oman 1
QA - Qatar 1
SV - El Salvador 1
SY - Repubblica araba siriana 1
TG - Togo 1
TJ - Tagikistan 1
WS - Samoa 1
Totale 26.538
Città #
Milan 3.337
Jacksonville 1.193
San Jose 1.074
Singapore 930
Fairfield 928
Ashburn 866
Chandler 783
Woodbridge 609
Hong Kong 557
Wilmington 429
Ann Arbor 424
Houston 410
Izmir 406
Princeton 398
Seattle 390
Beijing 367
Dearborn 366
Nyköping 297
Dublin 296
Dallas 292
Cambridge 287
Dong Ket 268
Boardman 236
The Dalles 235
Rome 234
Lauterbourg 173
Council Bluffs 157
San Mateo 138
New York 133
Los Angeles 106
Ho Chi Minh City 102
Como 91
Toronto 86
Helsinki 84
Chicago 80
Hanoi 79
San Diego 77
Ogden 69
Orem 69
Santa Clara 69
Guangzhou 59
Munich 53
São Paulo 53
Düsseldorf 45
Chennai 40
Tokyo 40
Warsaw 36
Hefei 35
Mexico City 34
Verona 33
Brussels 31
London 31
Manchester 29
Nanjing 28
Frankfurt am Main 26
Hangzhou 25
Norwalk 25
Shanghai 22
Turku 22
Boston 21
Kunming 21
Phoenix 21
Montreal 20
Pune 20
Amsterdam 19
Brooklyn 19
Denver 19
Johannesburg 19
Jinan 18
Falls Church 17
Stockholm 17
Da Nang 16
Fuzhou 16
San Francisco 16
Washington 16
Columbus 15
Shenzhen 15
St Petersburg 15
Atlanta 14
Haiphong 14
Poplar 14
Zhengzhou 12
Belo Horizonte 11
Mumbai 11
Nuremberg 10
Baghdad 9
Brasília 9
Buffalo 9
Changsha 9
Curitiba 9
Kocaeli 9
Ankara 8
Kilburn 8
Nanchang 8
Porto Alegre 8
Querétaro 8
Rio de Janeiro 8
Tianjin 8
Chongqing 7
Dhaka 7
Totale 18.342
Nome #
CIITA-driven MHC class ii expressing tumor cells can efficiently prime naive CD4+ TH cells in vivo and vaccinate the host against parental MHC-II-negative tumor cells 270
Boosting the MHC class II-restricted tumor antigen presentation to CD4+ T helper cells: A critical issue for triggering protective immunity and re-orienting the tumor microenvironment toward an anti-tumor state 247
Cytoplasmic Localization of HTLV-1 HBZ Protein: A Biomarker of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) 236
Adequate Antigen Availability: A Key Issue for Novel Approaches to Tumor Vaccination and Tumor Immunotherapy 226
Active suppression of the class II transactivator-encoding AIR-1 locus is responsible for the lack of major histocompatibility complex class II gene expression observed during differentiation from B cells to plasma cells 217
Tripartite Motif-Containing Protein 22 Interacts with Class II Transactivator and Orchestrates Its Recruitment in Nuclear Bodies Containing TRIM19/PML and Cyclin T1 217
Cell lineage-specific and developmental stage-specific controls of MHC class-II-antigen expression. 215
Typing of a polymorphic human gene conferring susceptibility to insulin-dependent diabetes mellitus by picosecond-resolved FRET on non-purified/non-amplified genomic DNA 212
Localization, quantification and interaction with host factors of endogenous HTLV-1 HBZ protein in infected cells and ATL 210
CIITA-induced MHC class II expression in mammary adenocarcinoma leads to a Th1 polarization of the tumor microenvironment, tumor rejection and specific anti-tumor memory. 207
A girl with Diabetes and severe Combined Immunodeficiency from Adenosine Deaminase Deficiency 207
CIITA-induced MHC class II expression in mammary adenocarcinoma leads to a TH1 polarization of the tumor microenvironment, tumor rejection, and specific antitumor memory 206
The MHC-II transactivator CIITA inhibits Tax-1-mediated HTLV-1 expression and NF-kB activation 205
CIITA-induced MHC class II expression in mammary adenocarcinoma leads to a Th1 polarization of the tumor microenvironment, tumor rejection, and specific anti-tumor memory 204
The MHC-II transactivator CIITA, a restriction factor against oncogenic HTLV-1 and HTLV-2 retroviruses: similarities and differences in the inhibition of Tax-1 and Tax-2 viral transactivators 203
The MHC-II transactivator CIITA inhibits Tat function and HIV-1 replication in human myeloid cells 203
The MHC Class II transactivator CIITA inhibits the persistent activation of NF-kB by Tax-1 197
Picosecond-resolved FRET on non-amplified DNA for identifying individuals genetically susceptible to type-1 diabetes 194
The MHC class II transactivator: prey and hunter in infectious diseases 191
Localization, quantization and interaction with host factors of endogenous HTLV-1 HBZ protein in infected cells and ATL 191
Autoimmunità e Malattie Autoimmuni 189
Molecular and cellular correlates of the CIITA-mediated inhibition of HTLV-2 Tax-2 transactivator function resulting in loss of viral replication 186
Adequate Antigen Availability (AAA) in antitumor immunity: Definition and consequences for novel strategies of tumor prevention and antitumor treatment 184
Proteomic analysis of dopamine and α-synuclein interplay in a cellular model of Parkinson's disease pathogenesis 182
Assessment of the DQB1-DQA1 complete genotype allows best prediction for IDDM 179
The HLA class II transcriptional activator blocks the function of HIV-1 Tat and inhibits viral replication 178
Tumor Immunology meets Immunology: Modified cancer cells as professional APC for priming naïve tumor-specific CD4+ T cells 178
The MHC-II transactivator CIITA inhibits Tax-1-mediated HTLV-1 expression and NF-kB activation 176
The MHC class II transactivator CIITA inhibits Tax-1-mediated HTLV-1 expression and NF-kB activation. 176
Insight into the molecular mechanism of CIITA-mediated inhibition of HIV-1 and HTLV transactivators 175
Neonatal Fc receptor is involved in the protection of fibrinogen after its intake in peripheral blood mononuclear cells 174
A dual defensive role of CIITA against retroviral infections 172
The MHC-II transactivator CIITA, a viral restriction factor inhibiting the replication of Human T cell Lymphotropic virus type 1. 171
Multi-omics discovery of exome-derived neoantigens in hepatocellular carcinoma 169
Time-Resolved Förster Resonance Energy Transfer Analysis of Single-Nucleotide Polymorphisms: Towards Molecular Typing of Genes on Non-Purified and Non-PCR-Amplified DNA 167
New approaches of cancer vaccination and cancer immunotherapy based on the optimal stimulation of tumor-specific, MHC class II-restricted CD4+ T helper cells 166
Block of Stat-1 activation in macrophages, undergoing bacterial phagocytosis causes CIITA reduced transcription and consequent impaired antigen presentation 164
MHC class II enhanceosome: how is the class II transactivator recruited to DNA-bound activators? 164
Associazione tra genotipo HLA-DQ e suscettibilità al Diabete insulino-Dipendente 164
CIITA dependent MHC class II IA expression in tumor cells triggers CD4 T cell protective and long lasting antitumor immunity 160
Major histocompatibility complex class II transcriptional platform: assembly of nuclear factor Y and regulatory factor X (RFX) on DNA requires RFX5 dimers 159
MHC class II transactivator CIITA inhibits Tax-2-mediated HTLV-2 LTR transactivation and viral replication by binding to and affecting Tax-2 intracellular localization 159
HLA-DQ genotype in early onset insulin dependent diabetes mellitus 158
The MHC-II transactivator CIITA inhibits Tat-mediated HIV-1 LTR transactivation and virus replication in human U937 monocytic cells 158
Tax-1-mediated HTLV-1 replication and NF-kB activation is inhibited by the MHC-II transactivator CIITA 158
Fowlpoxvirus recombinants coding for the CIITA gene increase the expression of endogenous MHC-II and Fowlpox Gag/Pro and Env SIV transgenes 158
MHC class II gene regulation: some historical considerations on a still ontogenetic and phylogenetic puzzle 157
A new strategy of tumor vaccination based on mammary adenocarcinoma cells transduced with the MHC class II transactivator CIITA 157
Tax-1-mediated NF-kB activation is inhibited by the MHC-II transactivator CIITA 157
HIV-1 Tat mutants in the cysteine-rich region down-regulate HLA class II expression in T lymphocytic and macrophage cell lines 157
Distinct regulation of HLA class II and class I cell surface expression in THP-1 macrophage cell line after bacterial phagocytosis 156
Tat protein is an HIV-1 encoded SS-chemochine homolog that promotes migrationand upregulates CCR3 on human FceRI+ cells 156
Analysis of microchimerism in thyroid autoimmune diseases 156
Highly stable oligomerization forms of HIV-1 Tat detected by monoclonal antibodies and requirement of monomeric forms for the transactivating function on the HIV-1 LTR 155
Phosphorylation of CIITA directs its oligomerization, accumulation and increased activity on MHCII promoters 155
Apparente dissociazione tra fenotipo DR e genotipo MHC di classe II in IDDM 155
Molecular and Cellular Correlates of the CIITA-Mediated Inhibition of HTLV-2 Tax-2 Transactivator Function Resulting in Loss of Viral Replication. 152
Molecular typing of polymorphic genes by time-resolved fluorescence resonance energy transfer 151
Analysis of a combined immunodeficiency patient with defect in MHCII expression (BLS) reveals the presence of several mutant isoforms of RFXANK mRNA 150
The MHC class II transactivator CIITA inhibits the persistent activation of NF-kB by Human T cell Lymphotropic Virus type-1 Tax-1 oncoprotein 148
Distinct subcellular localization of HTLV-1 HBZ oncoprotein in the ATL leukemic and HAM/TSP patients. 148
Role of the HLA-DQ genotype in IDDM susceptibility 147
Transient internalization and/or block of export to the cell surface of HLA Class II and CD1B molecules after mycobacterial phagocytosis 147
The MHC-II transactivator CIITA, a viral restriction factor inhibiting the replication of Human T cell Lymphotropic virus type 1 146
The Major Histocompatibility Complex Class II Transactivator CIITA Inhibits the Persistent Activation of NF-kappa B by the Human T Cell Lymphotropic Virus Type 1 Tax-1 Oncoprotein 146
Transient internalization and/or block of export to the cell surface of HLA Class II and CD1b molecules after bacterial phagocytosis 144
The MHC-II transactivator CIITA is a viral restriction factor against HIV-1 replication 144
HLA-DQB1 typing of north east italian IDDM patients using amplified DNA, oligonucleotide probes and a rapid DNA-Enzyme Immunoassay (DEIA) 143
CIITA blocks the function of HIV-1 Tat by competing for cyclin T1 and inhibits viral replication 143
CIITA reduced transcription as the cause of HLA class II down-modulation in human macrophages during bacterial phagocytosis 142
Optimal MHC-II-restricted tumor antigen presentation to CD4+ T helper cells: the key issue for development of anti-tumor vaccines 142
Inhibition of Human T-Cell Leukemia virus type 2 (HTLV-2) replication by the suppressive action of CIITA and NF-Y 141
The MHC Class II transactivator, CIITA,is a viral restriction factor for human oncogenic retroviruses 141
The MHC class II transactivator (CIITA): a physiologic inhibitor of HTLV-2 retroviral infection. 141
HTLV2 influence on pathways regulating proliferation and death in B cell line BJAB 141
The complex interplay of the DQB1 and DQA1 loci in the generation of the susceptible and protective phenotype for Insulin-Dependent Diabetes Mellitus 141
HTLV-2 Tax-2 transactivator increases the expression and the function of its inhibitor CIITA, the master regulator of HLA-II gene transcription 140
The molecular basis of the inhibition of HTLV-2 retroviral replication by the MHC class II transactivator (CIITA) 140
The MHC class II transactivator (CIITA): a physiologic inhibitor of HIV1 and HTLV2 retroviral infections 140
A new strategy of tumor vaccination based on tumor cells transduced with the MHC class II transactivator CIITA 138
Associazione tra HLA-DQB1 e diabete giovanile analizzata a livello molecolare per Southern e DEIA 138
Cellular and molecular aspects of immune response relevant to autoimmune diseases 138
Expression of MHC class I and class II antigens in pancreatic adenocarcinomas 137
The MHC-II transactivator CIITA, a viral restriction factor inhibiting the replication of Human T cell Lymphotropic Virus Type 1 136
The constitutive activation of NF-kB by HTLV-1 Tax-1 oncoprotein is inhibited by the MHC class II transactivator CIITA 136
Tumor treatment by TNF-alpha targeted to tumor vessels and melphalan induces strong adaptive immune response, protection from tumor growth and anti-tumor memory. 135
Inhibition of human T cell leukemia virus type 2 (HTLV-2) replication by the suppressive action of class II transactivator and nuclear factor Y 134
The MHC class II transactivator, CIITA, blocks the transcriptional activity of both HTLV-2 Tax-2 and HTLV-1 Tax-1 134
Host-retrovirus interaction: role of CIITA in the inhibition of HTLV-1 replication and oncogenic potential 134
TPA-mediated down-regulation of MHC class II gene expression in human macrophage precursors by destabilization of the MHC-II transactivator (CIITA) mRNA 131
Efficient antigen presentation and T cell activation by MHC class II molecules of CIITA-transfected epatocarcinoma cells 130
Regulation of HLA antigen expression in HIV infected cells 130
Human T-cell leukemia virus type II directly acts on CD34+ hematopoietic precursors by increasing their survival potential. Envelope associated HLA class II molecules reverse this effect 129
The MHC-II transactivator CIITA is a viral restriction factor against HIV-1 replication 127
Control of mammary adenocarcinoma growth in vivo by gene therapy with the MHC class II transactivator CIITA 126
The MHC class II transactivator (CIITA): a "physiologic" drug against HIV-1 replication 126
Approcci immunogenetici per il controllo dell'infezione da retrovirus umani 126
Characterization of an epigenetic variant lacking MHC-II inducibility by IFN-g in the promyelocytic cell line THP-1 125
HLA class II expression in uninducible hepatocarcinoma cells after transfection of AIR-1 gene product CIITA. Acquisition of antigen processing and presentation capacity. 125
Evidence for a specific post- transcriptional mechanism controlling the expression of HLA-DQ, but not DR and DP molecules 125
Totale 16.321
Categoria #
all - tutte 102.971
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 102.971


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021532 0 0 0 0 0 0 0 0 0 0 0 532
2021/20221.700 211 223 152 133 42 48 57 123 83 222 159 247
2022/20232.159 252 86 120 258 159 493 0 292 312 63 69 55
2023/20244.884 816 801 919 824 877 310 50 40 155 20 9 63
2024/20252.562 10 45 483 50 107 108 123 141 313 158 220 804
2025/20266.064 492 363 187 862 539 448 1.407 371 620 413 246 116
Totale 26.604