TOSI, GIOVANNA
 Distribuzione geografica
Continente #
NA - Nord America 10.077
EU - Europa 8.517
AS - Asia 4.207
SA - Sud America 468
AF - Africa 52
Continente sconosciuto - Info sul continente non disponibili 8
OC - Oceania 4
Totale 23.333
Nazione #
US - Stati Uniti d'America 9.890
IT - Italia 4.320
UA - Ucraina 1.555
SG - Singapore 1.428
CN - Cina 739
VN - Vietnam 674
TR - Turchia 653
DE - Germania 580
SE - Svezia 577
HK - Hong Kong 512
FI - Finlandia 428
BR - Brasile 419
IE - Irlanda 298
RU - Federazione Russa 242
GB - Regno Unito 227
FR - Francia 134
CA - Canada 126
IN - India 57
MX - Messico 49
PL - Polonia 42
JP - Giappone 39
BE - Belgio 32
ZA - Sudafrica 25
ES - Italia 22
AR - Argentina 18
BD - Bangladesh 18
NL - Olanda 17
IQ - Iraq 15
KR - Corea 11
LT - Lituania 11
MA - Marocco 10
PK - Pakistan 10
AE - Emirati Arabi Uniti 8
EC - Ecuador 8
EU - Europa 8
CH - Svizzera 7
IR - Iran 7
CZ - Repubblica Ceca 6
SA - Arabia Saudita 6
VE - Venezuela 6
ID - Indonesia 5
PY - Paraguay 5
UZ - Uzbekistan 5
CO - Colombia 4
KE - Kenya 4
LB - Libano 4
TN - Tunisia 4
TW - Taiwan 4
AT - Austria 3
BY - Bielorussia 3
DZ - Algeria 3
JM - Giamaica 3
PE - Perù 3
RS - Serbia 3
AU - Australia 2
BH - Bahrain 2
CI - Costa d'Avorio 2
CL - Cile 2
GR - Grecia 2
HR - Croazia 2
IL - Israele 2
KH - Cambogia 2
MT - Malta 2
NZ - Nuova Zelanda 2
PA - Panama 2
TT - Trinidad e Tobago 2
UY - Uruguay 2
AO - Angola 1
BB - Barbados 1
CR - Costa Rica 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
EG - Egitto 1
GA - Gabon 1
GY - Guiana 1
HN - Honduras 1
JO - Giordania 1
KW - Kuwait 1
KZ - Kazakistan 1
ME - Montenegro 1
MK - Macedonia 1
NO - Norvegia 1
PH - Filippine 1
PR - Porto Rico 1
PS - Palestinian Territory 1
QA - Qatar 1
TG - Togo 1
Totale 23.333
Città #
Milan 3.337
Jacksonville 1.193
Fairfield 928
Chandler 783
Singapore 778
Ashburn 763
Woodbridge 609
Hong Kong 511
Wilmington 429
Ann Arbor 424
Houston 409
Izmir 406
Princeton 398
Seattle 389
Dearborn 366
Beijing 329
Nyköping 297
Dublin 296
Cambridge 287
Dallas 285
Dong Ket 268
Boardman 235
Rome 231
San Mateo 138
The Dalles 127
New York 117
Los Angeles 98
Como 91
Toronto 85
San Diego 76
Ogden 69
Munich 53
Santa Clara 52
São Paulo 51
Düsseldorf 45
Chicago 44
Council Bluffs 44
Tokyo 38
Warsaw 36
Helsinki 35
Hefei 34
Verona 33
Ho Chi Minh City 32
Brussels 31
London 30
Mexico City 28
Nanjing 28
Orem 28
Hanoi 27
Guangzhou 25
Norwalk 25
Turku 22
Boston 21
Phoenix 21
Frankfurt am Main 20
Pune 20
Brooklyn 19
Kunming 19
Johannesburg 18
Denver 17
Falls Church 17
Manchester 17
Stockholm 17
Jinan 16
Washington 16
Montreal 15
St Petersburg 15
Chennai 14
Columbus 14
Poplar 14
Fuzhou 13
San Francisco 13
Amsterdam 11
Belo Horizonte 11
Atlanta 10
San Jose 10
Kocaeli 9
Shanghai 9
Ankara 8
Brasília 8
Buffalo 8
Curitiba 8
Hangzhou 8
Kilburn 8
Nanchang 8
Nuremberg 8
Porto Alegre 8
Querétaro 8
Rio de Janeiro 8
Changsha 7
Hebei 7
Raleigh 7
Salt Lake City 7
Tehran 7
Xian 7
Zhengzhou 7
Auburn Hills 6
Chongqing 6
Guarulhos 6
Miami 6
Totale 16.050
Nome #
CIITA-driven MHC class ii expressing tumor cells can efficiently prime naive CD4+ TH cells in vivo and vaccinate the host against parental MHC-II-negative tumor cells 239
Boosting the MHC class II-restricted tumor antigen presentation to CD4+ T helper cells: A critical issue for triggering protective immunity and re-orienting the tumor microenvironment toward an anti-tumor state 227
Cytoplasmic Localization of HTLV-1 HBZ Protein: A Biomarker of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) 226
Active suppression of the class II transactivator-encoding AIR-1 locus is responsible for the lack of major histocompatibility complex class II gene expression observed during differentiation from B cells to plasma cells 204
Tripartite Motif-Containing Protein 22 Interacts with Class II Transactivator and Orchestrates Its Recruitment in Nuclear Bodies Containing TRIM19/PML and Cyclin T1 200
A girl with Diabetes and severe Combined Immunodeficiency from Adenosine Deaminase Deficiency 196
Cell lineage-specific and developmental stage-specific controls of MHC class-II-antigen expression. 195
Localization, quantification and interaction with host factors of endogenous HTLV-1 HBZ protein in infected cells and ATL 193
The MHC-II transactivator CIITA inhibits Tax-1-mediated HTLV-1 expression and NF-kB activation 189
CIITA-induced MHC class II expression in mammary adenocarcinoma leads to a Th1 polarization of the tumor microenvironment, tumor rejection, and specific anti-tumor memory 186
The MHC-II transactivator CIITA inhibits Tat function and HIV-1 replication in human myeloid cells 185
Adequate Antigen Availability: A Key Issue for Novel Approaches to Tumor Vaccination and Tumor Immunotherapy 184
The MHC class II transactivator: prey and hunter in infectious diseases 183
CIITA-induced MHC class II expression in mammary adenocarcinoma leads to a Th1 polarization of the tumor microenvironment, tumor rejection and specific anti-tumor memory. 182
Picosecond-resolved FRET on non-amplified DNA for identifying individuals genetically susceptible to type-1 diabetes 177
The MHC Class II transactivator CIITA inhibits the persistent activation of NF-kB by Tax-1 176
The MHC-II transactivator CIITA, a restriction factor against oncogenic HTLV-1 and HTLV-2 retroviruses: similarities and differences in the inhibition of Tax-1 and Tax-2 viral transactivators 174
Autoimmunità e Malattie Autoimmuni 174
Typing of a polymorphic human gene conferring susceptibility to insulin-dependent diabetes mellitus by picosecond-resolved FRET on non-purified/non-amplified genomic DNA 173
Localization, quantization and interaction with host factors of endogenous HTLV-1 HBZ protein in infected cells and ATL 169
CIITA-induced MHC class II expression in mammary adenocarcinoma leads to a TH1 polarization of the tumor microenvironment, tumor rejection, and specific antitumor memory 168
Proteomic analysis of dopamine and α-synuclein interplay in a cellular model of Parkinson's disease pathogenesis 166
The MHC class II transactivator CIITA inhibits Tax-1-mediated HTLV-1 expression and NF-kB activation. 165
The HLA class II transcriptional activator blocks the function of HIV-1 Tat and inhibits viral replication 164
Molecular and cellular correlates of the CIITA-mediated inhibition of HTLV-2 Tax-2 transactivator function resulting in loss of viral replication 162
Assessment of the DQB1-DQA1 complete genotype allows best prediction for IDDM 161
The MHC-II transactivator CIITA inhibits Tax-1-mediated HTLV-1 expression and NF-kB activation 157
Tumor Immunology meets Immunology: Modified cancer cells as professional APC for priming naïve tumor-specific CD4+ T cells 157
Adequate Antigen Availability (AAA) in antitumor immunity: Definition and consequences for novel strategies of tumor prevention and antitumor treatment 156
Multi-omics discovery of exome-derived neoantigens in hepatocellular carcinoma 155
Insight into the molecular mechanism of CIITA-mediated inhibition of HIV-1 and HTLV transactivators 154
A dual defensive role of CIITA against retroviral infections 153
The MHC-II transactivator CIITA, a viral restriction factor inhibiting the replication of Human T cell Lymphotropic virus type 1. 152
Neonatal Fc receptor is involved in the protection of fibrinogen after its intake in peripheral blood mononuclear cells 152
MHC class II gene regulation: some historical considerations on a still ontogenetic and phylogenetic puzzle 151
HIV-1 Tat mutants in the cysteine-rich region down-regulate HLA class II expression in T lymphocytic and macrophage cell lines 151
Distinct regulation of HLA class II and class I cell surface expression in THP-1 macrophage cell line after bacterial phagocytosis 149
Phosphorylation of CIITA directs its oligomerization, accumulation and increased activity on MHCII promoters 149
Block of Stat-1 activation in macrophages, undergoing bacterial phagocytosis causes CIITA reduced transcription and consequent impaired antigen presentation 148
HLA-DQ genotype in early onset insulin dependent diabetes mellitus 148
MHC class II enhanceosome: how is the class II transactivator recruited to DNA-bound activators? 147
Associazione tra genotipo HLA-DQ e suscettibilità al Diabete insulino-Dipendente 147
Time-Resolved Förster Resonance Energy Transfer Analysis of Single-Nucleotide Polymorphisms: Towards Molecular Typing of Genes on Non-Purified and Non-PCR-Amplified DNA 146
Major histocompatibility complex class II transcriptional platform: assembly of nuclear factor Y and regulatory factor X (RFX) on DNA requires RFX5 dimers 145
Highly stable oligomerization forms of HIV-1 Tat detected by monoclonal antibodies and requirement of monomeric forms for the transactivating function on the HIV-1 LTR 144
MHC class II transactivator CIITA inhibits Tax-2-mediated HTLV-2 LTR transactivation and viral replication by binding to and affecting Tax-2 intracellular localization 144
Fowlpoxvirus recombinants coding for the CIITA gene increase the expression of endogenous MHC-II and Fowlpox Gag/Pro and Env SIV transgenes 144
The MHC-II transactivator CIITA inhibits Tat-mediated HIV-1 LTR transactivation and virus replication in human U937 monocytic cells 143
CIITA dependent MHC class II IA expression in tumor cells triggers CD4 T cell protective and long lasting antitumor immunity 142
Analysis of microchimerism in thyroid autoimmune diseases 141
A new strategy of tumor vaccination based on mammary adenocarcinoma cells transduced with the MHC class II transactivator CIITA 141
Tax-1-mediated HTLV-1 replication and NF-kB activation is inhibited by the MHC-II transactivator CIITA 141
New approaches of cancer vaccination and cancer immunotherapy based on the optimal stimulation of tumor-specific, MHC class II-restricted CD4+ T helper cells 141
Analysis of a combined immunodeficiency patient with defect in MHCII expression (BLS) reveals the presence of several mutant isoforms of RFXANK mRNA 139
Molecular and Cellular Correlates of the CIITA-Mediated Inhibition of HTLV-2 Tax-2 Transactivator Function Resulting in Loss of Viral Replication. 139
Tax-1-mediated NF-kB activation is inhibited by the MHC-II transactivator CIITA 138
The MHC class II transactivator CIITA inhibits the persistent activation of NF-kB by Human T cell Lymphotropic Virus type-1 Tax-1 oncoprotein 138
Role of the HLA-DQ genotype in IDDM susceptibility 137
Apparente dissociazione tra fenotipo DR e genotipo MHC di classe II in IDDM 135
The complex interplay of the DQB1 and DQA1 loci in the generation of the susceptible and protective phenotype for Insulin-Dependent Diabetes Mellitus 135
The Major Histocompatibility Complex Class II Transactivator CIITA Inhibits the Persistent Activation of NF-kappa B by the Human T Cell Lymphotropic Virus Type 1 Tax-1 Oncoprotein 134
The MHC-II transactivator CIITA, a viral restriction factor inhibiting the replication of Human T cell Lymphotropic virus type 1 133
Molecular typing of polymorphic genes by time-resolved fluorescence resonance energy transfer 131
The MHC-II transactivator CIITA is a viral restriction factor against HIV-1 replication 131
Tat protein is an HIV-1 encoded SS-chemochine homolog that promotes migrationand upregulates CCR3 on human FceRI+ cells 130
Inhibition of Human T-Cell Leukemia virus type 2 (HTLV-2) replication by the suppressive action of CIITA and NF-Y 130
Transient internalization and/or block of export to the cell surface of HLA Class II and CD1b molecules after bacterial phagocytosis 130
Transient internalization and/or block of export to the cell surface of HLA Class II and CD1B molecules after mycobacterial phagocytosis 130
Distinct subcellular localization of HTLV-1 HBZ oncoprotein in the ATL leukemic and HAM/TSP patients. 130
Expression of MHC class I and class II antigens in pancreatic adenocarcinomas 128
HLA-DQB1 typing of north east italian IDDM patients using amplified DNA, oligonucleotide probes and a rapid DNA-Enzyme Immunoassay (DEIA) 128
CIITA blocks the function of HIV-1 Tat by competing for cyclin T1 and inhibits viral replication 128
HTLV-2 Tax-2 transactivator increases the expression and the function of its inhibitor CIITA, the master regulator of HLA-II gene transcription 128
Cellular and molecular aspects of immune response relevant to autoimmune diseases 126
The MHC Class II transactivator, CIITA,is a viral restriction factor for human oncogenic retroviruses 125
Associazione tra HLA-DQB1 e diabete giovanile analizzata a livello molecolare per Southern e DEIA 124
CIITA reduced transcription as the cause of HLA class II down-modulation in human macrophages during bacterial phagocytosis 124
Host-retrovirus interaction: role of CIITA in the inhibition of HTLV-1 replication and oncogenic potential 124
The constitutive activation of NF-kB by HTLV-1 Tax-1 oncoprotein is inhibited by the MHC class II transactivator CIITA 124
Optimal MHC-II-restricted tumor antigen presentation to CD4+ T helper cells: the key issue for development of anti-tumor vaccines 123
The MHC-II transactivator CIITA, a viral restriction factor inhibiting the replication of Human T cell Lymphotropic Virus Type 1 123
A new strategy of tumor vaccination based on tumor cells transduced with the MHC class II transactivator CIITA 122
The MHC class II transactivator, CIITA, blocks the transcriptional activity of both HTLV-2 Tax-2 and HTLV-1 Tax-1 121
The MHC class II transactivator (CIITA): a physiologic inhibitor of HIV1 and HTLV2 retroviral infections 121
Tumor treatment by TNF-alpha targeted to tumor vessels and melphalan induces strong adaptive immune response, protection from tumor growth and anti-tumor memory. 120
Efficient antigen presentation and T cell activation by MHC class II molecules of CIITA-transfected epatocarcinoma cells 119
HTLV2 influence on pathways regulating proliferation and death in B cell line BJAB 119
Therapy-induced antitumor vaccination by targeting TNFa to tumor vessels in combination with melphalan 116
Regulation of HLA antigen expression in HIV infected cells 116
Human T-cell leukemia virus type II directly acts on CD34+ hematopoietic precursors by increasing their survival potential. Envelope associated HLA class II molecules reverse this effect 115
The MHC class II transactivator (CIITA): a physiologic inhibitor of HTLV-2 retroviral infection. 115
Control of mammary adenocarcinoma growth in vivo by gene therapy with the MHC class II transactivator CIITA 114
Evidence for a specific post- transcriptional mechanism controlling the expression of HLA-DQ, but not DR and DP molecules 114
TPA-mediated down-regulation of MHC class II gene expression in human macrophage precursors by destabilization of the MHC-II transactivator (CIITA) mRNA 114
The molecular basis of the inhibition of HTLV-2 retroviral replication by the MHC class II transactivator (CIITA) 114
The MHC-II transactivator CIITA, a viral restriction factor inhibiting the replication of Human T cell Lymphotropic Virus Type 1 113
Approcci immunogenetici per il controllo dell'infezione da retrovirus umani 113
CIITA, the Master Regulator of MHC Class II Gene Transcription, Targets the Viral Transactivator Tax-1 to Inhibit HTLV-I Viral Replication and NFKB Activation 112
The MHC class II transactivator (CIITA): a "physiologic" drug against HIV-1 replication 112
HTLV-II Tax-2 increases the cell surface expression of HLA-II molecules by acting at the level of CIITA, the master regulator of HLA-II transcription 110
Totale 14.661
Categoria #
all - tutte 92.784
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 92.784


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.949 0 0 0 0 0 272 83 287 431 102 242 532
2021/20221.700 211 223 152 133 42 48 57 123 83 222 159 247
2022/20232.159 252 86 120 258 159 493 0 292 312 63 69 55
2023/20244.884 816 801 919 824 877 310 50 40 155 20 9 63
2024/20252.562 10 45 483 50 107 108 123 141 313 158 220 804
2025/20262.859 492 363 187 862 539 416 0 0 0 0 0 0
Totale 23.399