statistiche ricercatore

SACCHI, SILVIA

Distribuzione geografica

Continente	#
NA - Nord America	12.318
EU - Europa	7.088
AS - Asia	4.619
SA - Sud America	693
Continente sconosciuto - Info sul continente non disponibili	177
AF - Africa	77
OC - Oceania	45
Totale	25.017

Salva come PNG Salva come JPEG

Nazione	#
US - Stati Uniti d'America	11.963
IT - Italia	3.729
SG - Singapore	1.441
CN - Cina	1.092
UA - Ucraina	1.023
VN - Vietnam	647
BR - Brasile	587
SE - Svezia	559
TR - Turchia	548
HK - Hong Kong	516
FI - Finlandia	321
DE - Germania	297
IE - Irlanda	269
GB - Regno Unito	243
FR - Francia	209
CA - Canada	186
RU - Federazione Russa	164
IN - India	79
MX - Messico	69
BD - Bangladesh	62
JP - Giappone	62
CZ - Repubblica Ceca	50
AU - Australia	42
ES - Italia	33
NL - Olanda	33
AR - Argentina	32
BE - Belgio	30
PL - Polonia	30
ZA - Sudafrica	29
AT - Austria	24
IQ - Iraq	24
PK - Pakistan	24
EC - Ecuador	23
CO - Colombia	20
EU - Europa	18
ID - Indonesia	18
LT - Lituania	17
CR - Costa Rica	15
IL - Israele	14
SV - El Salvador	14
CH - Svizzera	13
JM - Giamaica	13
NG - Nigeria	13
TT - Trinidad e Tobago	13
AE - Emirati Arabi Uniti	11
NI - Nicaragua	10
CL - Cile	9
CW - ???statistics.table.value.countryCode.CW???	9
AZ - Azerbaigian	8
JO - Giordania	8
GT - Guatemala	7
KE - Kenya	7
KR - Corea	7
MA - Marocco	7
MD - Moldavia	7
MY - Malesia	7
NP - Nepal	7
PR - Porto Rico	7
HN - Honduras	6
PE - Perù	6
SA - Arabia Saudita	6
VE - Venezuela	6
DZ - Algeria	5
PH - Filippine	5
RO - Romania	5
UZ - Uzbekistan	5
BG - Bulgaria	4
BO - Bolivia	4
GE - Georgia	4
GP - Guadalupe	4
KZ - Kazakistan	4
PT - Portogallo	4
PY - Paraguay	4
AL - Albania	3
CU - Cuba	3
GR - Grecia	3
HU - Ungheria	3
MT - Malta	3
PA - Panama	3
PS - Palestinian Territory	3
SC - Seychelles	3
CI - Costa d'Avorio	2
EE - Estonia	2
EG - Egitto	2
ET - Etiopia	2
LK - Sri Lanka	2
LV - Lettonia	2
NO - Norvegia	2
NZ - Nuova Zelanda	2
OM - Oman	2
SK - Slovacchia (Repubblica Slovacca)	2
SN - Senegal	2
SY - Repubblica araba siriana	2
TN - Tunisia	2
AG - Antigua e Barbuda	1
AM - Armenia	1
AO - Angola	1
BH - Bahrain	1
BJ - Benin	1
BN - Brunei Darussalam	1
Totale	24.847

Salva come PNG Salva come JPEG

Città	#
Milan	2.445
Ashburn	1.124
San Jose	1.089
Fairfield	966
Jacksonville	806
Singapore	755
Chandler	698
Woodbridge	635
Hong Kong	511
Council Bluffs	499
Seattle	396
Wilmington	393
Houston	360
Como	353
Ann Arbor	318
Dearborn	303
Princeton	298
Beijing	297
Nyköping	295
Cambridge	286
Dublin	263
Izmir	263
Dallas	235
The Dalles	217
Boardman	187
Dong Ket	181
Rome	171
Lauterbourg	135
Chicago	122
New York	120
Los Angeles	113
Ho Chi Minh City	107
San Mateo	86
Santa Clara	86
Helsinki	84
Toronto	74
Hanoi	73
Orem	73
San Diego	69
Munich	64
São Paulo	58
Tokyo	56
Ogden	54
Guangzhou	44
Mexico City	40
Washington	40
Denver	38
Chennai	37
Hefei	36
Kocaeli	36
London	36
Varese	33
Nanjing	30
Phoenix	30
Brooklyn	29
Brussels	28
Warsaw	28
Montreal	27
Olomouc	27
Atlanta	23
Redmond	23
Amsterdam	22
Kunming	22
Manchester	22
Poplar	22
Düsseldorf	21
Frankfurt am Main	21
Shanghai	21
Brno	20
Johannesburg	19
Rio de Janeiro	19
San Francisco	19
Turku	19
Haiphong	18
Verona	18
Naples	17
Norwalk	17
Tianjin	17
Boston	16
Buffalo	16
Da Nang	16
Bursa	15
Columbus	15
Ankara	14
Hangzhou	14
Mumbai	14
Redwood City	14
Shenzhen	14
Vienna	14
Belo Horizonte	13
Nanchang	13
North Bergen	13
Nuremberg	13
San José	13
Stockholm	13
Abuja	12
Changsha	12
Dhaka	12
Gavirate	12
Jinan	12
Totale	16.937

Salva come PNG Salva come JPEG

Nome	#
Synaptic and extrasynaptic NMDA receptors are gated by different endogenous coagonists.	448
Evidence for the interaction of d-amino acid oxidase with pLG72 in a glial cell line.	302
Structure-function relationships in human d-amino acid oxidase variants corresponding to known SNPs	284
Age-Related Changes in D-Aspartate Oxidase Promoter Methylation Control Extracellular D-Aspartate Levels and Prevent Precocious Cell Death during Brain Aging	273
Structure-function relationships in human D-amino acid oxidase.	270
Biosensors for D-amino acid detection	264
Effect of ligand binding on human D-amino acid oxidase: Implications for the development of new drugs for schizophrenia treatment	263
Characterization of human DAAO variants potentially related to an increased risk of schizophrenia	248
Modulating D-amino acid oxidase substrate specificity: production of an enzyme for analytical determination of all D-amino acids by directed evolution	242
Glial D-Serine Gates NMDA Receptors at Excitatory Synapses in Prefrontal Cortex.	236
Characterization of human D-amino acid oxidase	234
Human d-amino acid oxidase: The inactive G183R variant	233
A biosensor for all D-amino acids using evolved D-amino acid oxidase	228
Olanzapine, but not clozapine, increases glutamate release in the prefrontal cortex of freely moving mice by inhibiting D-aspartate oxidase activity	224
Determination of D-amino acids using a D-amino acid oxidase biosensor with spectrophotometric and potentiometric detection	222
D-amino acid oxidase inhibitors as a novel class of drugs for schizophrenia therapy	222
G72 primate-specific gene: a still enigmatic element in psychiatric disorders	222
Decreased free D-aspartate levels are linked to enhanced D-aspartate oxidase activity in the dorsolateral prefrontal cortex of schizophrenia patients	220
Deepening into the modulation of human D-amino acid oxidase	220
The degradation (by distinct pathways) of human D-amino acid oxidase and its interacting partner pLG72--two key proteins in D-serine catabolism in the brain.	217
Proline oxidase controls proline, glutamate, and glutamine cellular concentrations in a U87 glioblastoma cell line	217
Biochemical properties of human D-amino acid oxidase	216
Relevance of weak flavin binding in human D-amino acid oxidase	213
Investigating the role of active site residues of Rhodotorula gracilis D-amino acid oxidase on its substrate specificity.	211
Catalytic properties of D-amino acid oxidase in cephalosporin C bioconversion: A comparison between proteins from different sources	211
The levels of the NMDA receptor co-agonist D-serine are reduced in the substantia nigra of MPTP-lesioned macaques and in the cerebrospinal fluid of Parkinson’s disease patients	211
Human D-Amino Acid Oxidase: Structure, Function, and Regulation	208
Elucidating the role of the pLG72 R30K substitution in schizophrenia susceptibility	204
Active site and reaction mechanism of Rhodotorula gracilis D-amino acid oxidase: a crystallographic and site-directed mutagenesis approach	203
Regulating levels of the neuromodulator d-serine in human brain: structural insight into pLG72 and d-amino acid oxidase interaction	203
Expression in Escherichia coli and in vitro refolding of the human protein pLG72	202
Active site and reaction mechanism of Rhodotorula gracilis D-amino acid oxidase:a crystallographic and site-directed mutagenesis approach	201
Is rat an appropriate animal model to study the involvement of d-serine catabolism in schizophrenia? insights from characterization of d-amino acid oxidase.	201
Reduced D-serine levels in the nucleus accumbens of cocaine-treated rats hinder the induction of NMDA receptor-dependent synaptic plasticity	200
Role of tyrosine 238 in the active site of Rhodotorula gracilis D-amino acid oxidase - A site-directed mutagenesis study	197
High-Throughput Screening Strategy Identifies Allosteric, Covalent Human D-Amino Acid Oxidase Inhibitor	197
Active site of yeast D-amino acid oxidase: mutations and inferences	196
Cellular studies on human D-aspartate oxidase	195
Active site of yeast D-amino acid oxidase:mutations and inferences	194
The Freshwater Cyanobacterium Leptolymbya sp. FP1: PSP Toxins detection and genetic identification	193
Optimization of glutaryl-7-aminocephalosporanic acid acylase expression in E.coli	193
D-Serine and Glycine Differentially Control Neurotransmission during Visual Cortex Critical Period	193
Biochemical properties of human D-amino acid oxidase variants and their potential significance in pathologies	192
Physiological functions of D-amino acid oxidases: from yeast to humans.	191
The role of tyrosines 223 and 238 in Rhodotorula gracilis D-amino acid oxidase catalysis: Interpretation of double mutations	189
Novel insights into renal d-amino acid oxidase accumulation: propiverine changes DAAO localization and peroxisomal size in vivo	189
The freshwater cyanobacterium Planktothrix SP.FP1: molecular identification and detection of paralytic shellfish poisoning toxins	188
Understanding renal nuclear protein accumulation: an in vitro approach to explain an in vivo phenomenon	188
Engineering the Properties of D-Amino Acid Oxidases by a Rational and a Directed Evolution Approach.	184
Co-agonists differentially tune GluN2B-NMDA receptor trafficking at hippocampal synapses	182
Identity of the NMDA receptor coagonist is synapse specific and developmentally regulated in the hippocampus	179
Characterization of human D-amino acid oxidase, a flavoenzyme involved in neurotransmission regulation	176
Properties and applications of microbial D-amino acid oxidases: Current state and perspectives	176
Metabolic resistance of the D-peptide RD2 developed for direct elimination of amyloid-β oligomers	176
Could D-serine serum levels be considered a biomarker in Alzheimer’s disease?	174
Role of human DAAO in D-serine metabolism: new insight	173
Glial D-serine gates NMDA receptors at excitatory synapses in prefrontal cortex	172
... And now saxitoxin-producing cyanobacteria in Europe	171
Structural basis of D-aspartate oxidase properties	170
Characterization of human DAAO variants potentially related to an increased risk to schizophrenia	167
Modulation of the activity and stability of human D-amino acid oxidase by the interaction with small ligands.	167
Characterization of the G183R inactive human D-amino acid oxidase variant	167
Free D-aspartate triggers NMDA receptor-dependent cell death in primary cortical neurons and perturbs JNK activation, Tau phosphorylation, and protein SUMOylation in the cerebral cortex of mice lacking D-aspartate oxidase activity	165
An antibody-based enzymatic therapy for cancer treatment: The selective localization of D-amino acid oxidase to EDA fibronectin	164
pLG72 modulates intracellular D-serine levels through its interaction with D-amino acid oxidase - Effect on schizophrenia susceptibility	163
Identity of endogenous NMDAR glycine site agonist in amygdala is determined by synaptic activity level.	163
Engineering the substrate specificity of D-amino-acid oxidase	162
D-Serine metabolism in the brain: the role of D-amino acid oxidase	162
D-amino acid oxidase variants related to human pathologies	162
Biocatalysis and biocatalyst production	161
Glycine oxidase from Bacillus subtilis: Role of Histidine 244 and Methionine 261.	160
Serum D-serine levels are altered in early phases of Alzheimer’s disease: towards a precocious biomarker	159
Antimicrobial D-amino acid oxidase-derived peptides specify gut microbiota	155
Biochemical characterization of mouse D-aspartate oxidase	155
Yin and Yang in Post-Translational Modifications of Human D-Amino Acid Oxidase	154
Metabolism of the neuromodulator D-serine	153
Evolution of novel enzyme specificities from a common scaffold	152
Structure and function of Rhodotorula gracilis D-amino acid oxidase. 1. Site-directed mutagenesis of tyrosines 223 and 238	150
Detection of D-amino acids by D-amino acid oxidase.	150
Toxic cyanobacterial blooms in lake Varese (Italy): a multidisciplinary approach	149
“Directed evolution”: un nuovo approccio di ingegneria proteica	148
Insight into pLG72 and D-amino acid oxidase interaction	147
DNA methylation landscape of the genes regulating D-serine and D-aspartate metabolism in post-mortem brain from controls and subjects with schizophrenia	147
Biochemical Properties and Physiological Functions of pLG72: Twenty Years of Investigations	145
Role of the highly conserved Tyr223 and Tyr238 of yeast D-amino acid oxidase	145
pLG72-mediated modulation of hDAAO functionality: an intriguing issue	145
Engineering the substrate specificity of D-amino acid oxidase: a rational design approach	143
On the mechanism of Rhodotorula gracilis D-amino acid oxidase: role of the active site serine 335	143
Structure and function of Rhodothorula gracilis D-amino acid oxidase. 1. Site-directed mutagenesis of tyrosine 223 and 238	142
Role of the highly conserved Tyr223 and Tyr238 of yeast D-amino acid oxidase	141
Insulin and serine metabolism as sex-specific hallmarks of Alzheimer's disease in the human hippocampus	139
Combinatorial and computational challenges to design the substrate specificity of D-amino acid oxidase	139
D-Serine metabolism by human D-amino acid oxidase: filling the voids	139
Examination of pLG72 and D-Amino Acid Oxidase interaction as molecular basis of Schizophrenia.	138
In vivo studies on the D-amino acid oxidase-pLG72 interaction in human brain	138
Enzyme factory: engineering of new biocatalysts strating from a common scaffold.	138
Investigating the molecular basis of schizophrenia: the effect of pLG72 interaction on the functionality of human D-amino acid oxidase	137
Engineering the substrate specificity of D-amino acid oxidase: a directed evolution approach	136
Effect of binding of small ligands on the activity and stability of human D-amino acid oxidase:implications for the design of novel drugs for schizophrenia treatment	136
Deepen human D-amino acid oxidase properties to get insight in D-serine metabolism.	134
Totale	18.761

Salva come PNG Salva come JPEG

Categoria	#
all - tutte	106.242
article - articoli	0
book - libri	0
conference - conferenze	0
curatela - curatele	0
other - altro	0
patent - brevetti	0
selected - selezionate	0
volume - volumi	0
Totale	106.242

Salva come PNG Salva come JPEG

	Totale	Lug	Ago	Sett	Ott	Nov	Dic	Gen	Feb	Mar	Apr	Mag	Giu
2021/2022	970	0	0	0	77	101	36	94	107	72	179	120	184
2022/2023	1.898	170	89	153	213	154	441	7	240	253	76	47	55
2023/2024	3.695	592	590	630	653	720	219	15	48	93	31	17	87
2024/2025	2.594	14	46	387	91	140	163	140	229	310	242	280	552
2025/2026	5.897	410	289	256	788	607	385	1.179	366	677	484	253	203
2026/2027	1.778	176	280	792	530	0	0	0	0	0	0	0	0
Totale													25.017