PILONE, MIRELLA
 Distribuzione geografica
Continente #
NA - Nord America 7.262
EU - Europa 6.616
AS - Asia 3.523
SA - Sud America 451
AF - Africa 38
Continente sconosciuto - Info sul continente non disponibili 18
OC - Oceania 5
Totale 17.913
Nazione #
US - Stati Uniti d'America 7.166
IT - Italia 3.383
UA - Ucraina 1.240
SG - Singapore 1.078
TR - Turchia 763
CN - Cina 638
SE - Svezia 579
VN - Vietnam 452
HK - Hong Kong 404
BR - Brasile 402
FI - Finlandia 341
DE - Germania 274
IE - Irlanda 252
GB - Regno Unito 177
RU - Federazione Russa 152
JP - Giappone 58
FR - Francia 53
CA - Canada 52
IN - India 42
MX - Messico 36
CZ - Repubblica Ceca 30
BE - Belgio 24
ZA - Sudafrica 23
ES - Italia 22
PL - Polonia 21
AR - Argentina 20
BD - Bangladesh 17
EU - Europa 17
LT - Lituania 13
NL - Olanda 10
AT - Austria 9
CO - Colombia 9
IL - Israele 9
IQ - Iraq 9
PK - Pakistan 8
CH - Svizzera 7
BG - Bulgaria 6
CL - Cile 6
EC - Ecuador 6
ID - Indonesia 6
SA - Arabia Saudita 6
AE - Emirati Arabi Uniti 5
TN - Tunisia 5
AZ - Azerbaigian 4
KE - Kenya 4
LU - Lussemburgo 4
MY - Malesia 4
AU - Australia 3
MA - Marocco 3
PT - Portogallo 3
RO - Romania 3
VE - Venezuela 3
DO - Repubblica Dominicana 2
DZ - Algeria 2
EE - Estonia 2
HU - Ungheria 2
JM - Giamaica 2
JO - Giordania 2
KZ - Kazakistan 2
OM - Oman 2
PA - Panama 2
PE - Perù 2
PY - Paraguay 2
RS - Serbia 2
SY - Repubblica araba siriana 2
UZ - Uzbekistan 2
AL - Albania 1
AO - Angola 1
BH - Bahrain 1
BT - Bhutan 1
BY - Bielorussia 1
CR - Costa Rica 1
GR - Grecia 1
HR - Croazia 1
IR - Iran 1
KG - Kirghizistan 1
KI - Kiribati 1
LB - Libano 1
LK - Sri Lanka 1
LV - Lettonia 1
MK - Macedonia 1
MN - Mongolia 1
MO - Macao, regione amministrativa speciale della Cina 1
NI - Nicaragua 1
NP - Nepal 1
NZ - Nuova Zelanda 1
PH - Filippine 1
SK - Slovacchia (Repubblica Slovacca) 1
UY - Uruguay 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 17.913
Città #
Milan 2.559
Jacksonville 925
Chandler 789
Singapore 582
Fairfield 511
Ashburn 485
Hong Kong 404
Izmir 383
Woodbridge 326
Dearborn 318
Princeton 312
Nyköping 309
Wilmington 293
Beijing 270
Dublin 250
Seattle 209
Ann Arbor 201
Houston 188
Dong Ket 185
Dallas 184
Cambridge 181
Rome 180
Boardman 173
San Mateo 145
The Dalles 119
Chicago 92
Como 79
Los Angeles 65
Ogden 62
New York 58
Tokyo 55
São Paulo 47
San Diego 44
Kocaeli 39
Ho Chi Minh City 37
Santa Clara 37
Hefei 34
Nanjing 33
Munich 31
Düsseldorf 30
Kunming 27
London 26
Washington 25
Brussels 24
Verona 24
Orem 23
Toronto 23
Warsaw 21
Atlanta 18
Hanoi 18
Nanchang 18
Brooklyn 17
Chennai 17
Guangzhou 17
Johannesburg 17
Montreal 17
Norwalk 17
Olomouc 16
Turku 16
Denver 15
Mexico City 15
Helsinki 14
Poplar 14
Boston 13
Redwood City 13
Brno 12
Council Bluffs 12
Jinan 12
Belo Horizonte 11
Curitiba 11
Frankfurt am Main 11
Manchester 11
Rio de Janeiro 11
Fuzhou 10
San Francisco 10
Ankara 9
Phoenix 9
Stockholm 9
Amsterdam 7
Chongqing 7
Shenyang 7
Buenos Aires 6
Columbus 6
Des Moines 6
Edinburgh 6
Falls Church 6
Juiz de Fora 6
New Delhi 6
Parma 6
Querétaro 6
Shanghai 6
Xian 6
Auburn Hills 5
Brasília 5
Duque de Caxias 5
Hangzhou 5
Istanbul 5
Nuremberg 5
Redmond 5
São José 5
Totale 11.954
Nome #
Modulating D-amino acid oxidase substrate specificity: production of an enzyme for analytical determination of all D-amino acids by directed evolution 212
A biosensor for all D-amino acids using evolved D-amino acid oxidase 202
Characterization of human D-amino acid oxidase 196
Relevance of weak flavin binding in human D-amino acid oxidase 191
Investigating the role of active site residues of Rhodotorula gracilis D-amino acid oxidase on its substrate specificity. 189
Catalytic properties of D-amino acid oxidase in cephalosporin C bioconversion: A comparison between proteins from different sources 187
Contribution of the dimeric state to the thermal stability of the flavoprotein D-amino acid oxidase 186
Active site and reaction mechanism of Rhodotorula gracilis D-amino acid oxidase: a crystallographic and site-directed mutagenesis approach 180
Analyzing the d-amino acid content in biological samples by engineered enzymes 178
Dissecting the structural determinants of the stability of cholesterol oxidase containing covalently bound flavin 173
The role of tyrosines 223 and 238 in Rhodotorula gracilis D-amino acid oxidase catalysis: Interpretation of double mutations 170
Optimization of glutaryl-7-aminocephalosporanic acid acylase expression in E.coli 170
Expression in Escherichia coli and in vitro refolding of the human protein pLG72 168
Yeast D-amino acid oxidase: structural basis of its catalytic properties 161
Active site and reaction mechanism of Rhodotorula gracilis D-amino acid oxidase:a crystallographic and site-directed mutagenesis approach 161
Evolution of an acylase active on cephalosporin C 161
A "molten globule"-like intermediate in the unfolding of the peroxisomal flavoprotein D-amino acid oxidase 161
Active site of yeast D-amino acid oxidase: mutations and inferences 155
D-amino acid oxidase: new findings 155
Characterization of a D-amino acid oxidase microbiosensor for D-serine detection in the central nervous system. 155
Active site of yeast D-amino acid oxidase:mutations and inferences 155
Physiological functions of D-amino acid oxidases: from yeast to humans. 152
Kinetic mechanisms of glycine oxidase from Bacillus subtilis 150
Tryptophan 243 affects interprotein contacts, cofactor binding and stability in D-amino acid oxidase from Rhodotorula gracilis 147
Yeast D-amino acid oxidase: Structural basis of its catalytic properties 146
The x-ray structure of D-amino acid oxidase at very high resolution identifies the chemical mechanism of flavin-dependent substrate dehydrogenation 146
Properties and applications of microbial D-amino acid oxidases: Current state and perspectives 145
Studies on the reaction mechanism of Rhodotorula gracilis D-amino-acid oxidase - Role of the highly conserved Tyr-223 on substrate binding and catalysis 144
Characterization of a yeast D-amino acid oxidase microbiosensor for D-serine detection in the central nervous system 144
On the oxygen reactivity of cholesterol oxidase. 143
Redox potentials and their pH dependence of D-amino-acid oxidase of Rhodotorula gracilis and Trigonopsis variabilis 143
Yeast D-amino acid oxidase: structural basis of its catalytic properties 141
D-amino acid oxidase as an industrial biocatalyst 140
Glycine oxidase from Bacillus subtilis: Role of Histidine 244 and Methionine 261. 140
Glycine oxidase from Bacillus subtilis - Characterization of a new flavoprotein 138
Role of tyrosine 238 in the active site of Rhodotorula gracilis D-amino acid oxidase - A site-directed mutagenesis study 138
Characterization of the new flavoprotein glycine oxidase from Bacillus subtilis 134
Effect of the oligomerization state on the thermal stability of yeast D-amino acid oxidase 133
Characterization of the new flavoprotein glycine oxidase from Bacillus subtilis 133
A "molten globule" - like intermediate in the unfolding of the flavoprotein D-amino acid oxidase 133
Unfolding intermediate in the peroxisomal flavoprotein D-amino acid oxidase 131
Dissection of the structural determinants involved in formation of the dimeric form of D-amino acid oxidase from Rhodotorula gracilis: role of the size of the beta F5-beta F6 loop 130
Kinetic mechanisms of cholesterol oxidase from Streptomyces hygroscopicus and Brevibacterium sterolicum 129
Structure-function relationships in glycine oxidase from Bacillus subtilis 129
Structure and function of Rhodotorula gracilis D-amino acid oxidase. 1. Site-directed mutagenesis of tyrosines 223 and 238 128
Evolution of novel enzyme specificities from a common scaffold 128
Ruolo della dimerizzazione nel flavoenzima D-amino acido ossidasi da Rhodotorula gracilis 127
Regulation of D-amino acid oxidase expression in the yeast Rhodotorula gracilis 126
On the mechanism of Rhodotorula gracilis D-amino acid oxidase: role of the active site serine 335 126
Cholesterol oxidase from Brevibacterium sterolicum and Streptomices hygroscopicus: a covalent FAD binding vs. a non-covalent one 125
Detection of D-amino acids by D-amino acid oxidase. 125
Engineering the substrate specificity of D-amino-acid oxidase 125
Biocatalysis and biocatalyst production 124
Conversion of the dimeric D-amino acid oxidase from Rhodotorula gracilis to a monomeric form. A rational mutagenesis approach 123
Characterization of D-Amino Acid Oxidase Microbiosensor for D-Serina detection in the central nervous system. 122
Glycine oxiadse from Bacillus subtilis: role of the histidine 244 and methionine 261 122
Role of the highly conserved Tyr223 and Tyr238 of yeast D-amino acid oxidase 121
Evolution of a Cephalosporin C Acylase. 120
Investigating the metabolic role of glycine oxidase from Bacillus subtilis 120
Modulation of the oxygen affinity of D-amino acid oxidase: production of evolved variants for a cancer enzyme 118
Cloning and characterization of human and Xenopus allantoicase 117
Site-directed mutagenesis and thermodynamic studies reveal the role of dimeric oligomerization state in yeast D-amino acid oxidase 115
Reaction mechanism of glycine oxidase, a new flavoenzyme active on glycine 114
Examination of pLG72 and D-Amino Acid Oxidase interaction as molecular basis of Schizophrenia. 114
pLG72 modulates intracellular D-serine levels through its interaction with D-amino acid oxidase - Effect on schizophrenia susceptibility 114
Characterization of human D-amino acid oxidase, a flavoenzyme involved in neurotransmission regulation 113
Role of the C-terminal portion of yeast D-amino acid oxidase in stability and in aggregation state 113
Structure-function correlation in glycine oxidase from Bacillus subtilis 113
Very high resolution crystallographic structures of D-amino acid oxidase complexed with substrate and various ligands 112
Structure-function relationships in glycine oxidase from Bacillus subtilis 112
Enzyme factory: engineering of new biocatalysts strating from a common scaffold. 112
Investigation of the oxygen reactivity if D-amino acid oxidase: production of evolved variants for gene therapy. 112
Cholesterol oxidase from Brevibacterium sterolicum and Streptomyces hygroscopicus: a covalent FAD binding vs. a non-covalent one 111
Role of the highly conserved Tyr223 and Tyr238 of yeast D-amino acid oxidase 110
Studies on the elimination reaction of Rhodotorula gracilis D-amino acid oxidase with beta-chloro-D-alanine 110
In vivo studies on the D-amino acid oxidase-pLG72 interaction in human brain 110
On the oxygen reactivity of flavoprotein oxidase. An oxygen access tunnel and gate in Brevibacterium sterolicum cholesterol oxidase. 110
Engineering the substrate specificity of D-amino acid oxidase: a rational design approach 109
On the oxygen reactivity of flavooxidase 109
Cholesterol oxidase from Brevibacterium sterolicum - The relationship between covalent flavinylation and redox properties 108
Thermal stability of yeast D-amino acid oxidase: Deconvoluting the contributions of the dimeric aggregation state 108
Investigating D-Amino Acid Oxidase and pLG72 as potential targets of the antipsychotic drug chlorpromazine. 108
Structure and function of Rhodothorula gracilis D-amino acid oxidase. 1. Site-directed mutagenesis of tyrosine 223 and 238 108
Engineering the substrate specificity of D-amino acid oxidase: a directed evolution approach 107
Engineering a new D-amino acid oxidase: an evoluted enzyme and its applications 107
Glycine oxidase from Bacillus subtilis: role of histidine 244 and methionine 261 107
Combinatorial and computational challenges to design the substrate specificity of D-amino acid oxidase 106
Engineering the D-amino acid oxidase from Rhodotorula gracilis to facilitate its downstream processing 105
Reaction mechanism of flavin dehydrogenation by D-amino acid oxidase 105
Investigating the molecular basis of schizophrenia: the effect of pLG72 interaction on the functionality of human D-amino acid oxidase 105
Engineering the substrate specificity of D-amino acid oxidase by rational and irrational design 104
Structure and function of Rhodotorula gracilis D-amino acid oxidase: site-directed mutagenesis of arginine 285 104
Novel drugs for schizophrenia treatment: the mechanism of human D-amino acid oxidase inhibition 104
Rational design of a novel specificity of D-amino acid oxidase: towards the biosensor for all D-amino acids? 103
Very high resolution crystal structure of D-amino Acid oxidase. Insights into the reaction mechanism and mode of ligand binding 103
Techniques for the engineering of D-amino acid oxidase substrate specificity 103
Overexpression of a recombinant wild-type and His-tagged Bacillus subtilis glycine oxidase in Escherichia coli 102
Role of the beta12-beta13 loop of yeast D-amino acid oxidase on stability and on aggregation: a rational design and thermodynamic study 101
Kinetic mechanism of cholesterol oxidase from Streptomyces hygroscopicus and Brevibacterium sterolicum 101
Kinetic mechanism of glycine oxidase 101
Totale 13.185
Categoria #
all - tutte 73.833
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 73.833


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.303 0 0 0 0 0 199 37 164 341 77 188 297
2021/20221.383 157 183 157 92 58 19 64 87 78 189 104 195
2022/20232.069 183 96 160 229 164 478 0 308 283 54 60 54
2023/20243.794 655 655 662 656 726 211 11 33 88 23 15 59
2024/20252.048 12 17 402 52 64 144 65 171 217 203 149 552
2025/20262.208 375 256 125 668 569 215 0 0 0 0 0 0
Totale 17.932