PILONE, MIRELLA
 Distribuzione geografica
Continente #
NA - Nord America 10.206
EU - Europa 7.029
AS - Asia 4.531
SA - Sud America 512
AF - Africa 65
Continente sconosciuto - Info sul continente non disponibili 42
OC - Oceania 17
Totale 22.402
Nazione #
US - Stati Uniti d'America 9.984
IT - Italia 3.481
SG - Singapore 1.345
UA - Ucraina 1.241
CN - Cina 1.043
TR - Turchia 765
VN - Vietnam 637
SE - Svezia 592
HK - Hong Kong 453
BR - Brasile 435
FI - Finlandia 377
DE - Germania 284
IE - Irlanda 253
FR - Francia 221
GB - Regno Unito 212
RU - Federazione Russa 158
CA - Canada 112
IN - India 74
JP - Giappone 68
MX - Messico 49
ES - Italia 34
BD - Bangladesh 33
CZ - Repubblica Ceca 31
BE - Belgio 27
ZA - Sudafrica 27
AR - Argentina 25
NL - Olanda 25
PL - Polonia 24
EU - Europa 17
IQ - Iraq 17
CO - Colombia 16
AU - Australia 15
LT - Lituania 14
CR - Costa Rica 12
PK - Pakistan 12
IL - Israele 11
CL - Cile 10
AT - Austria 9
EC - Ecuador 9
JM - Giamaica 9
ID - Indonesia 8
TN - Tunisia 8
AE - Emirati Arabi Uniti 7
CH - Svizzera 7
SV - El Salvador 7
TT - Trinidad e Tobago 7
VE - Venezuela 7
AZ - Azerbaigian 6
BG - Bulgaria 6
GT - Guatemala 6
KE - Kenya 6
PR - Porto Rico 6
SA - Arabia Saudita 6
DZ - Algeria 5
EE - Estonia 5
MA - Marocco 5
MY - Malesia 5
PH - Filippine 5
PT - Portogallo 5
UZ - Uzbekistan 5
CW - ???statistics.table.value.countryCode.CW??? 4
JO - Giordania 4
KZ - Kazakistan 4
LU - Lussemburgo 4
MD - Moldavia 4
NI - Nicaragua 4
PA - Panama 4
PE - Perù 4
SY - Repubblica araba siriana 4
EG - Egitto 3
HU - Ungheria 3
NG - Nigeria 3
NP - Nepal 3
PY - Paraguay 3
RO - Romania 3
UY - Uruguay 3
AO - Angola 2
DO - Repubblica Dominicana 2
ET - Etiopia 2
IR - Iran 2
LB - Libano 2
OM - Oman 2
RS - Serbia 2
SC - Seychelles 2
XK - ???statistics.table.value.countryCode.XK??? 2
AL - Albania 1
AM - Armenia 1
BB - Barbados 1
BH - Bahrain 1
BM - Bermuda 1
BT - Bhutan 1
BY - Bielorussia 1
CY - Cipro 1
GA - Gabon 1
GP - Guadalupe 1
GR - Grecia 1
HN - Honduras 1
HR - Croazia 1
KG - Kirghizistan 1
KI - Kiribati 1
Totale 22.373
Città #
Milan 2.568
San Jose 1.044
Jacksonville 926
Ashburn 851
Chandler 789
Singapore 702
Fairfield 511
Hong Kong 451
Council Bluffs 444
Izmir 383
Woodbridge 326
Dearborn 319
Princeton 312
Nyköping 309
Beijing 297
Wilmington 293
Dublin 250
Seattle 212
Dallas 204
Ann Arbor 201
Houston 194
Rome 192
Chicago 185
Dong Ket 185
Cambridge 181
Boardman 173
The Dalles 171
San Mateo 146
Lauterbourg 137
Ho Chi Minh City 103
Los Angeles 93
New York 82
Como 79
Orem 67
Hanoi 65
Ogden 62
Santa Clara 62
São Paulo 62
Tokyo 60
Guangzhou 55
Helsinki 50
San Diego 49
Toronto 42
Kocaeli 39
Chennai 36
Hefei 34
Nanjing 34
London 31
Munich 31
Düsseldorf 30
Washington 29
Kunming 28
Manchester 26
Verona 26
Atlanta 24
Brussels 24
Tianjin 24
Mexico City 23
Shanghai 22
Warsaw 22
Brooklyn 21
Johannesburg 20
Montreal 20
Nanchang 19
Denver 18
Amsterdam 17
Frankfurt am Main 17
Norwalk 17
Hangzhou 16
Olomouc 16
Turku 16
Haiphong 15
Phoenix 15
Poplar 15
San Francisco 15
Shenzhen 15
Boston 14
Jinan 14
Buffalo 13
Da Nang 13
Redwood City 13
Belo Horizonte 12
Brno 12
Miami 12
Curitiba 11
Rio de Janeiro 11
Ankara 10
Fuzhou 10
Memphis 10
Mumbai 10
Columbus 9
San José 9
Stockholm 9
Charlotte 8
Chongqing 8
Des Moines 8
Las Vegas 8
Naples 8
New Delhi 8
Zhengzhou 8
Totale 14.890
Nome #
Modulating D-amino acid oxidase substrate specificity: production of an enzyme for analytical determination of all D-amino acids by directed evolution 241
Characterization of human D-amino acid oxidase 234
Contribution of the dimeric state to the thermal stability of the flavoprotein D-amino acid oxidase 232
A "molten globule"-like intermediate in the unfolding of the peroxisomal flavoprotein D-amino acid oxidase 230
A biosensor for all D-amino acids using evolved D-amino acid oxidase 228
Analyzing the d-amino acid content in biological samples by engineered enzymes 217
Relevance of weak flavin binding in human D-amino acid oxidase 213
Investigating the role of active site residues of Rhodotorula gracilis D-amino acid oxidase on its substrate specificity. 211
Catalytic properties of D-amino acid oxidase in cephalosporin C bioconversion: A comparison between proteins from different sources 211
Dissecting the structural determinants of the stability of cholesterol oxidase containing covalently bound flavin 208
Cloning and characterization of human and Xenopus allantoicase 206
Active site and reaction mechanism of Rhodotorula gracilis D-amino acid oxidase: a crystallographic and site-directed mutagenesis approach 203
Active site and reaction mechanism of Rhodotorula gracilis D-amino acid oxidase:a crystallographic and site-directed mutagenesis approach 201
Expression in Escherichia coli and in vitro refolding of the human protein pLG72 199
Active site of yeast D-amino acid oxidase: mutations and inferences 196
Role of tyrosine 238 in the active site of Rhodotorula gracilis D-amino acid oxidase - A site-directed mutagenesis study 196
Evolution of an acylase active on cephalosporin C 194
Active site of yeast D-amino acid oxidase:mutations and inferences 194
Optimization of glutaryl-7-aminocephalosporanic acid acylase expression in E.coli 193
Physiological functions of D-amino acid oxidases: from yeast to humans. 191
The role of tyrosines 223 and 238 in Rhodotorula gracilis D-amino acid oxidase catalysis: Interpretation of double mutations 189
Yeast D-amino acid oxidase: structural basis of its catalytic properties 188
Characterization of a D-amino acid oxidase microbiosensor for D-serine detection in the central nervous system. 187
Tryptophan 243 affects interprotein contacts, cofactor binding and stability in D-amino acid oxidase from Rhodotorula gracilis 186
D-amino acid oxidase: new findings 184
Kinetic mechanisms of glycine oxidase from Bacillus subtilis 183
Characterization of a yeast D-amino acid oxidase microbiosensor for D-serine detection in the central nervous system 182
Yeast D-amino acid oxidase: Structural basis of its catalytic properties 180
The x-ray structure of D-amino acid oxidase at very high resolution identifies the chemical mechanism of flavin-dependent substrate dehydrogenation 180
Characterization of human D-amino acid oxidase, a flavoenzyme involved in neurotransmission regulation 176
Characterization of D-Amino Acid Oxidase Microbiosensor for D-Serina detection in the central nervous system. 176
Properties and applications of microbial D-amino acid oxidases: Current state and perspectives 176
Glycine oxidase from Bacillus subtilis - Characterization of a new flavoprotein 174
Characterization of the new flavoprotein glycine oxidase from Bacillus subtilis 173
Kinetic mechanisms of cholesterol oxidase from Streptomyces hygroscopicus and Brevibacterium sterolicum 171
Studies on the reaction mechanism of Rhodotorula gracilis D-amino-acid oxidase - Role of the highly conserved Tyr-223 on substrate binding and catalysis 169
Yeast D-amino acid oxidase: structural basis of its catalytic properties 169
A "molten globule" - like intermediate in the unfolding of the flavoprotein D-amino acid oxidase 169
Redox potentials and their pH dependence of D-amino-acid oxidase of Rhodotorula gracilis and Trigonopsis variabilis 168
Ruolo della dimerizzazione nel flavoenzima D-amino acido ossidasi da Rhodotorula gracilis 166
Characterization of the new flavoprotein glycine oxidase from Bacillus subtilis 165
Regulation of D-amino acid oxidase expression in the yeast Rhodotorula gracilis 165
pLG72 modulates intracellular D-serine levels through its interaction with D-amino acid oxidase - Effect on schizophrenia susceptibility 163
Engineering the substrate specificity of D-amino-acid oxidase 162
Dissection of the structural determinants involved in formation of the dimeric form of D-amino acid oxidase from Rhodotorula gracilis: role of the size of the beta F5-beta F6 loop 161
D-amino acid oxidase as an industrial biocatalyst 161
Biocatalysis and biocatalyst production 161
On the oxygen reactivity of cholesterol oxidase. 160
Conversion of the dimeric D-amino acid oxidase from Rhodotorula gracilis to a monomeric form. A rational mutagenesis approach 160
Cholesterol oxidase from Brevibacterium sterolicum and Streptomices hygroscopicus: a covalent FAD binding vs. a non-covalent one 160
Glycine oxidase from Bacillus subtilis: Role of Histidine 244 and Methionine 261. 160
Very high resolution crystallographic structures of D-amino acid oxidase complexed with substrate and various ligands 159
Evolution of a Cephalosporin C Acylase. 156
Glycine oxiadse from Bacillus subtilis: role of the histidine 244 and methionine 261 152
Evolution of novel enzyme specificities from a common scaffold 152
Unfolding intermediate in the peroxisomal flavoprotein D-amino acid oxidase 152
Effect of the oligomerization state on the thermal stability of yeast D-amino acid oxidase 151
Structure-function relationships in glycine oxidase from Bacillus subtilis 151
Structure and function of Rhodotorula gracilis D-amino acid oxidase. 1. Site-directed mutagenesis of tyrosines 223 and 238 150
Detection of D-amino acids by D-amino acid oxidase. 150
On the oxygen reactivity of flavoprotein oxidase. An oxygen access tunnel and gate in Brevibacterium sterolicum cholesterol oxidase. 148
Investigating the metabolic role of glycine oxidase from Bacillus subtilis 146
Role of the highly conserved Tyr223 and Tyr238 of yeast D-amino acid oxidase 145
Engineering the substrate specificity of D-amino acid oxidase: a rational design approach 143
On the mechanism of Rhodotorula gracilis D-amino acid oxidase: role of the active site serine 335 143
Site-directed mutagenesis and thermodynamic studies reveal the role of dimeric oligomerization state in yeast D-amino acid oxidase 142
Cholesterol oxidase from Brevibacterium sterolicum and Streptomyces hygroscopicus: a covalent FAD binding vs. a non-covalent one 142
Structure and function of Rhodothorula gracilis D-amino acid oxidase. 1. Site-directed mutagenesis of tyrosine 223 and 238 142
Role of the highly conserved Tyr223 and Tyr238 of yeast D-amino acid oxidase 141
Cholesterol oxidase from Brevibacterium sterolicum - The relationship between covalent flavinylation and redox properties 140
Combinatorial and computational challenges to design the substrate specificity of D-amino acid oxidase 139
Kinetic mechanism of glycine oxidase 138
Examination of pLG72 and D-Amino Acid Oxidase interaction as molecular basis of Schizophrenia. 138
In vivo studies on the D-amino acid oxidase-pLG72 interaction in human brain 138
Enzyme factory: engineering of new biocatalysts strating from a common scaffold. 138
Reaction mechanism of glycine oxidase, a new flavoenzyme active on glycine 137
Investigating the molecular basis of schizophrenia: the effect of pLG72 interaction on the functionality of human D-amino acid oxidase 137
Modulation of the oxygen affinity of D-amino acid oxidase: production of evolved variants for a cancer enzyme therapy 137
Modulation of the oxygen affinity of D-amino acid oxidase: production of evolved variants for a cancer enzyme 137
Engineering the substrate specificity of D-amino acid oxidase: a directed evolution approach 136
Studies on the elimination reaction of Rhodotorula gracilis D-amino acid oxidase with beta-chloro-D-alanine 136
Structure-function relationships in glycine oxidase from Bacillus subtilis 135
Structure-function correlation in glycine oxidase from Bacillus subtilis 135
Engineering a new D-amino acid oxidase: an evoluted enzyme and its applications 133
Engineering the D-amino acid oxidase from Rhodotorula gracilis to facilitate its downstream processing 133
Investigation of the oxygen reactivity if D-amino acid oxidase: production of evolved variants for gene therapy. 133
Engineering the substrate specificity of D-amino acid oxidase by rational and irrational design 132
Investigating D-Amino Acid Oxidase and pLG72 as potential targets of the antipsychotic drug chlorpromazine. 132
Role of the beta12-beta13 loop of yeast D-amino acid oxidase on stability and on aggregation: a rational design and thermodynamic study 131
Role of the C-terminal portion of yeast D-amino acid oxidase in stability and in aggregation state 131
Structure and function of Rhodotorula gracilis D-amino acid oxidase: site-directed mutagenesis of arginine 285 131
On the oxygen reactivity of flavooxidase 131
Glycine oxidase from Bacillus subtilis: role of histidine 244 and methionine 261 130
Novel drugs for schizophrenia treatment: the mechanism of human D-amino acid oxidase inhibition 130
Thermal stability of yeast D-amino acid oxidase: Deconvoluting the contributions of the dimeric aggregation state 129
Techniques for the engineering of D-amino acid oxidase substrate specificity 128
Overexpression of a recombinant wild-type and His-tagged Bacillus subtilis glycine oxidase in Escherichia coli 127
Engineering the D-amino acid oxidase from Rhodotorula gracilis to facilitate its downstrem process 127
Reaction mechanism of glycine oxidase, a new flavoenzyme active on glycine 126
On the covalent link of the flavin cofactor in Cholesterol Oxidase. 126
Totale 16.318
Categoria #
all - tutte 90.683
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 90.683


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022886 0 0 0 92 58 19 64 87 78 189 104 195
2022/20232.069 183 96 160 229 164 478 0 308 283 54 60 54
2023/20243.794 655 655 662 656 726 211 11 33 88 23 15 59
2024/20252.048 12 17 402 52 64 144 65 171 217 203 149 552
2025/20265.124 375 256 125 668 569 329 1.167 354 560 370 212 139
2026/20271.554 104 262 689 499 0 0 0 0 0 0 0 0
Totale 22.402