statistiche ricercatore

PILONE, MIRELLA

Distribuzione geografica

Continente	#
EU - Europa	6.267
NA - Nord America	6.219
AS - Asia	1.656
Continente sconosciuto - Info sul continente non disponibili	17
SA - Sud America	9
OC - Oceania	4
AF - Africa	1
Totale	14.173

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Nazione	#
US - Stati Uniti d'America	6.201
IT - Italia	3.372
UA - Ucraina	1.233
TR - Turchia	746
SE - Svezia	574
CN - Cina	375
VN - Vietnam	367
FI - Finlandia	319
IE - Irlanda	251
DE - Germania	244
GB - Regno Unito	119
SG - Singapore	119
FR - Francia	51
JP - Giappone	32
CZ - Repubblica Ceca	30
BE - Belgio	22
EU - Europa	17
CA - Canada	14
RU - Federazione Russa	8
BR - Brasile	6
BG - Bulgaria	5
CH - Svizzera	5
IL - Israele	5
NL - Olanda	5
ES - Italia	4
LT - Lituania	4
LU - Lussemburgo	4
AU - Australia	3
IN - India	3
PK - Pakistan	3
CL - Cile	2
EE - Estonia	2
HU - Ungheria	2
MX - Messico	2
PL - Polonia	2
PT - Portogallo	2
RO - Romania	2
AE - Emirati Arabi Uniti	1
AR - Argentina	1
AT - Austria	1
BT - Bhutan	1
CR - Costa Rica	1
GR - Grecia	1
HR - Croazia	1
ID - Indonesia	1
IQ - Iraq	1
KE - Kenya	1
LV - Lettonia	1
MK - Macedonia	1
MO - Macao, regione amministrativa speciale della Cina	1
MY - Malesia	1
NZ - Nuova Zelanda	1
PA - Panama	1
RS - Serbia	1
SK - Slovacchia (Repubblica Slovacca)	1
Totale	14.173

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Città	#
Milan	2.558
Jacksonville	923
Chandler	789
Fairfield	511
Izmir	382
Woodbridge	326
Dearborn	318
Ashburn	312
Princeton	312
Nyköping	309
Wilmington	292
Dublin	250
Seattle	208
Ann Arbor	201
Dong Ket	185
Houston	182
Cambridge	181
Rome	178
Boardman	173
San Mateo	145
Beijing	123
Singapore	108
Como	79
Chicago	77
Ogden	62
San Diego	44
Kocaeli	39
Hefei	32
Nanjing	31
Düsseldorf	30
Tokyo	29
Kunming	27
Verona	24
Washington	24
Brussels	22
Los Angeles	21
Nanchang	18
Norwalk	17
Santa Clara	17
Olomouc	16
Guangzhou	15
London	14
New York	14
Munich	13
Redwood City	13
Brno	12
Jinan	12
Toronto	12
Dallas	9
Helsinki	8
Shenyang	7
Chongqing	6
Edinburgh	6
Falls Church	6
Parma	6
Xian	6
Auburn Hills	5
Frankfurt am Main	5
Fuzhou	5
Hangzhou	5
Redmond	5
Wenzhou	5
Hebei	4
Monza	4
Petah Tikva	4
Sofia	4
Stockholm	4
Wuhan	4
Zhengzhou	4
Brighton	3
Changsha	3
Madrid	3
Miami	3
Nanning	3
Pune	3
Trapani	3
Zurich	3
Acton	2
Amsterdam	2
Atlanta	2
Baotou	2
Bari	2
Besana in Brianza	2
Budapest	2
Casorezzo	2
Chengdu	2
Corsico	2
Gavirate	2
Harbin	2
Langfang	2
Leeds	2
Legnano	2
Lisbon	2
Mcallen	2
New Bedfont	2
Nuremberg	2
Pakistan	2
Paris	2
Phoenix	2
Prescot	2
Totale	9.862

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Nome	#
Modulating D-amino acid oxidase substrate specificity: production of an enzyme for analytical determination of all D-amino acids by directed evolution	181
Characterization of human D-amino acid oxidase	151
Relevance of weak flavin binding in human D-amino acid oxidase	151
A biosensor for all D-amino acids using evolved D-amino acid oxidase	150
Investigating the role of active site residues of Rhodotorula gracilis D-amino acid oxidase on its substrate specificity.	147
Yeast D-amino acid oxidase: structural basis of its catalytic properties	144
Catalytic properties of D-amino acid oxidase in cephalosporin C bioconversion: A comparison between proteins from different sources	142
Analyzing the d-amino acid content in biological samples by engineered enzymes	140
Optimization of glutaryl-7-aminocephalosporanic acid acylase expression in E.coli	138
Expression in Escherichia coli and in vitro refolding of the human protein pLG72	137
Dissecting the structural determinants of the stability of cholesterol oxidase containing covalently bound flavin	136
Evolution of an acylase active on cephalosporin C	135
Contribution of the dimeric state to the thermal stability of the flavoprotein D-amino acid oxidase	130
Physiological functions of D-amino acid oxidases: from yeast to humans.	130
Kinetic mechanisms of glycine oxidase from Bacillus subtilis	129
D-amino acid oxidase: new findings	129
Active site and reaction mechanism of Rhodotorula gracilis D-amino acid oxidase: a crystallographic and site-directed mutagenesis approach	129
The role of tyrosines 223 and 238 in Rhodotorula gracilis D-amino acid oxidase catalysis: Interpretation of double mutations	127
The x-ray structure of D-amino acid oxidase at very high resolution identifies the chemical mechanism of flavin-dependent substrate dehydrogenation	126
Tryptophan 243 affects interprotein contacts, cofactor binding and stability in D-amino acid oxidase from Rhodotorula gracilis	126
Redox potentials and their pH dependence of D-amino-acid oxidase of Rhodotorula gracilis and Trigonopsis variabilis	125
Studies on the reaction mechanism of Rhodotorula gracilis D-amino-acid oxidase - Role of the highly conserved Tyr-223 on substrate binding and catalysis	124
Yeast D-amino acid oxidase: Structural basis of its catalytic properties	123
On the oxygen reactivity of cholesterol oxidase.	122
Characterization of a D-amino acid oxidase microbiosensor for D-serine detection in the central nervous system.	122
Glycine oxidase from Bacillus subtilis: Role of Histidine 244 and Methionine 261.	120
Yeast D-amino acid oxidase: structural basis of its catalytic properties	119
D-amino acid oxidase as an industrial biocatalyst	117
Unfolding intermediate in the peroxisomal flavoprotein D-amino acid oxidase	117
Properties and applications of microbial D-amino acid oxidases: Current state and perspectives	116
Kinetic mechanisms of cholesterol oxidase from Streptomyces hygroscopicus and Brevibacterium sterolicum	114
Active site of yeast D-amino acid oxidase:mutations and inferences	112
Ruolo della dimerizzazione nel flavoenzima D-amino acido ossidasi da Rhodotorula gracilis	110
Effect of the oligomerization state on the thermal stability of yeast D-amino acid oxidase	107
Active site of yeast D-amino acid oxidase: mutations and inferences	107
Characterization of a yeast D-amino acid oxidase microbiosensor for D-serine detection in the central nervous system	107
Evolution of novel enzyme specificities from a common scaffold	107
Glycine oxidase from Bacillus subtilis - Characterization of a new flavoprotein	106
Active site and reaction mechanism of Rhodotorula gracilis D-amino acid oxidase:a crystallographic and site-directed mutagenesis approach	105
Glycine oxiadse from Bacillus subtilis: role of the histidine 244 and methionine 261	105
A "molten globule"-like intermediate in the unfolding of the peroxisomal flavoprotein D-amino acid oxidase	105
Role of the highly conserved Tyr223 and Tyr238 of yeast D-amino acid oxidase	103
On the mechanism of Rhodotorula gracilis D-amino acid oxidase: role of the active site serine 335	102
Regulation of D-amino acid oxidase expression in the yeast Rhodotorula gracilis	101
Engineering the substrate specificity of D-amino-acid oxidase	101
Structure-function relationships in glycine oxidase from Bacillus subtilis	98
Role of tyrosine 238 in the active site of Rhodotorula gracilis D-amino acid oxidase - A site-directed mutagenesis study	98
Studies on the elimination reaction of Rhodotorula gracilis D-amino acid oxidase with beta-chloro-D-alanine	96
Engineering the substrate specificity of D-amino acid oxidase: a rational design approach	96
Reaction mechanism of glycine oxidase, a new flavoenzyme active on glycine	95
Very high resolution crystallographic structures of D-amino acid oxidase complexed with substrate and various ligands	95
Role of the C-terminal portion of yeast D-amino acid oxidase in stability and in aggregation state	95
Cholesterol oxidase from Brevibacterium sterolicum and Streptomices hygroscopicus: a covalent FAD binding vs. a non-covalent one	95
Enzyme factory: engineering of new biocatalysts strating from a common scaffold.	94
On the oxygen reactivity of flavooxidase	94
Site-directed mutagenesis and thermodynamic studies reveal the role of dimeric oligomerization state in yeast D-amino acid oxidase	93
Role of the highly conserved Tyr223 and Tyr238 of yeast D-amino acid oxidase	93
Cloning and characterization of human and Xenopus allantoicase	93
Investigation of the oxygen reactivity if D-amino acid oxidase: production of evolved variants for gene therapy.	93
Characterization of the new flavoprotein glycine oxidase from Bacillus subtilis	92
Engineering a new D-amino acid oxidase: an evoluted enzyme and its applications	92
Engineering the D-amino acid oxidase from Rhodotorula gracilis to facilitate its downstream processing	92
Engineering the substrate specificity of D-amino acid oxidase by rational and irrational design	91
Thermal stability of yeast D-amino acid oxidase: Deconvoluting the contributions of the dimeric aggregation state	91
Examination of pLG72 and D-Amino Acid Oxidase interaction as molecular basis of Schizophrenia.	91
Structure and function of Rhodotorula gracilis D-amino acid oxidase. 1. Site-directed mutagenesis of tyrosines 223 and 238	90
Engineering the substrate specificity of D-amino acid oxidase: a directed evolution approach	90
Cholesterol oxidase from Brevibacterium sterolicum and Streptomyces hygroscopicus: a covalent FAD binding vs. a non-covalent one	89
On the oxygen reactivity of flavoprotein oxidase. An oxygen access tunnel and gate in Brevibacterium sterolicum cholesterol oxidase.	89
Structure and function of Rhodotorula gracilis D-amino acid oxidase: site-directed mutagenesis of arginine 285	88
Glycine oxidase from Bacillus subtilis: role of histidine 244 and methionine 261	88
pLG72 modulates intracellular D-serine levels through its interaction with D-amino acid oxidase - Effect on schizophrenia susceptibility	88
Combinatorial and computational challenges to design the substrate specificity of D-amino acid oxidase	88
Dissection of the structural determinants involved in formation of the dimeric form of D-amino acid oxidase from Rhodotorula gracilis: role of the size of the beta F5-beta F6 loop	87
Characterization of the new flavoprotein glycine oxidase from Bacillus subtilis	87
Overexpression of a recombinant wild-type and His-tagged Bacillus subtilis glycine oxidase in Escherichia coli	87
Rational design of a novel specificity of D-amino acid oxidase: towards the biosensor for all D-amino acids?	87
Characterization of D-Amino Acid Oxidase Microbiosensor for D-Serina detection in the central nervous system.	87
Evolution of a Cephalosporin C Acylase.	86
Investigating the metabolic role of glycine oxidase from Bacillus subtilis	86
Cholesterol oxidase from Brevibacterium sterolicum - The relationship between covalent flavinylation and redox properties	85
Conversion of the dimeric D-amino acid oxidase from Rhodotorula gracilis to a monomeric form. A rational mutagenesis approach	85
Reaction mechanism of flavin dehydrogenation by D-amino acid oxidase	85
A "molten globule" - like intermediate in the unfolding of the flavoprotein D-amino acid oxidase	85
Investigating the molecular basis of schizophrenia: the effect of pLG72 interaction on the functionality of human D-amino acid oxidase	85
Techniques for the engineering of D-amino acid oxidase substrate specificity	85
Role of the C-terminal portion of yeast D-amino acid oxidase in stability and aggregation state	83
Investigating D-Amino Acid Oxidase and pLG72 as potential targets of the antipsychotic drug chlorpromazine.	83
Kinetic mechanism of cholesterol oxidase from Streptomyces hygroscopicus and Brevibacterium sterolicum	82
Structure-function relationships in glycine oxidase from Bacillus subtilis	82
On the covalent link of the flavin cofactor in Cholesterol Oxidase.	82
Kinetic mechanism of glycine oxidase	81
Enzyme factory: engineering of new biocatalysts strating from a common scaffold	81
Modulation of the oxygen affinity of D-amino acid oxidase: production of evolved variants for a cancer enzyme therapy	81
Reaction mechanism of flavin dehydrogenation by D-amino acid oxidase	80
Studies on the elimination reaction of Rhodotorula gracilis D-amino acid oxidase with beta-chloro-D-alanine	80
Ligand-induced conformational changes in human D-amino acid oxidase	80
Characterization of human D-amino acid oxidase, a flavoenzyme involved in neurotransmission regulation	79
Structure and function of Rhodothorula gracilis D-amino acid oxidase. 1. Site-directed mutagenesis of tyrosine 223 and 238	79
Engineering the D-amino acid oxidase from Rhodotorula gracilis to facilitate its downstrem process	78
Totale	10.410

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Categoria	#
all - tutte	52.257
article - articoli	0
book - libri	0
conference - conferenze	0
curatela - curatele	0
other - altro	0
patent - brevetti	0
selected - selezionate	0
volume - volumi	0
Totale	52.257

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	Totale	Lug	Ago	Sett	Ott	Nov	Dic	Gen	Feb	Mar	Apr	Mag	Giu
2019/2020	1.557	0	0	0	0	72	267	368	293	101	242	38	176
2020/2021	1.754	19	178	29	188	37	199	37	164	341	77	188	297
2021/2022	1.383	157	183	157	92	58	19	64	87	78	189	104	195
2022/2023	2.069	183	96	160	229	164	478	0	308	283	54	60	54
2023/2024	3.794	655	655	662	656	726	211	11	33	88	23	15	59
2024/2025	516	12	17	402	52	33	0	0	0	0	0	0	0
Totale													14.192