PILONE, MIRELLA
 Distribuzione geografica
Continente #
NA - Nord America 7.215
EU - Europa 6.607
AS - Asia 3.476
SA - Sud America 447
AF - Africa 36
Continente sconosciuto - Info sul continente non disponibili 18
OC - Oceania 5
Totale 17.804
Nazione #
US - Stati Uniti d'America 7.121
IT - Italia 3.383
UA - Ucraina 1.240
SG - Singapore 1.040
TR - Turchia 763
CN - Cina 637
SE - Svezia 579
VN - Vietnam 452
HK - Hong Kong 401
BR - Brasile 398
FI - Finlandia 341
DE - Germania 274
IE - Irlanda 252
GB - Regno Unito 173
RU - Federazione Russa 152
JP - Giappone 57
FR - Francia 53
CA - Canada 50
IN - India 39
MX - Messico 36
CZ - Repubblica Ceca 30
BE - Belgio 24
ZA - Sudafrica 22
ES - Italia 21
AR - Argentina 20
PL - Polonia 20
BD - Bangladesh 17
EU - Europa 17
LT - Lituania 11
NL - Olanda 10
AT - Austria 9
CO - Colombia 9
IL - Israele 9
IQ - Iraq 9
PK - Pakistan 8
CH - Svizzera 7
BG - Bulgaria 6
CL - Cile 6
EC - Ecuador 6
ID - Indonesia 6
SA - Arabia Saudita 6
AE - Emirati Arabi Uniti 5
TN - Tunisia 5
AZ - Azerbaigian 4
LU - Lussemburgo 4
MY - Malesia 4
AU - Australia 3
KE - Kenya 3
MA - Marocco 3
RO - Romania 3
VE - Venezuela 3
DO - Repubblica Dominicana 2
DZ - Algeria 2
EE - Estonia 2
HU - Ungheria 2
JM - Giamaica 2
JO - Giordania 2
KZ - Kazakistan 2
OM - Oman 2
PA - Panama 2
PE - Perù 2
PT - Portogallo 2
PY - Paraguay 2
RS - Serbia 2
SY - Repubblica araba siriana 2
UZ - Uzbekistan 2
AL - Albania 1
AO - Angola 1
BH - Bahrain 1
BT - Bhutan 1
BY - Bielorussia 1
CR - Costa Rica 1
GR - Grecia 1
HR - Croazia 1
KG - Kirghizistan 1
KI - Kiribati 1
LB - Libano 1
LK - Sri Lanka 1
LV - Lettonia 1
MK - Macedonia 1
MN - Mongolia 1
MO - Macao, regione amministrativa speciale della Cina 1
NI - Nicaragua 1
NP - Nepal 1
NZ - Nuova Zelanda 1
PH - Filippine 1
SK - Slovacchia (Repubblica Slovacca) 1
UY - Uruguay 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 17.804
Città #
Milan 2.559
Jacksonville 925
Chandler 789
Singapore 546
Fairfield 511
Ashburn 475
Hong Kong 401
Izmir 383
Woodbridge 326
Dearborn 318
Princeton 312
Nyköping 309
Wilmington 293
Beijing 270
Dublin 250
Seattle 209
Ann Arbor 201
Houston 188
Dong Ket 185
Dallas 183
Cambridge 181
Rome 180
Boardman 173
San Mateo 145
The Dalles 119
Chicago 92
Como 79
Los Angeles 64
Ogden 62
Tokyo 54
New York 53
São Paulo 45
San Diego 44
Kocaeli 39
Ho Chi Minh City 37
Santa Clara 35
Hefei 34
Nanjing 33
Munich 31
Düsseldorf 30
Kunming 27
London 25
Washington 25
Brussels 24
Verona 24
Toronto 21
Warsaw 20
Atlanta 18
Hanoi 18
Nanchang 18
Guangzhou 17
Montreal 17
Norwalk 17
Brooklyn 16
Johannesburg 16
Olomouc 16
Turku 16
Mexico City 15
Orem 15
Chennai 14
Helsinki 14
Denver 13
Redwood City 13
Boston 12
Brno 12
Council Bluffs 12
Jinan 12
Belo Horizonte 11
Curitiba 11
Frankfurt am Main 11
Manchester 11
Poplar 11
Rio de Janeiro 11
Fuzhou 10
San Francisco 10
Ankara 9
Phoenix 9
Stockholm 9
Amsterdam 7
Chongqing 7
Shenyang 7
Buenos Aires 6
Columbus 6
Des Moines 6
Edinburgh 6
Falls Church 6
Juiz de Fora 6
New Delhi 6
Parma 6
Querétaro 6
Shanghai 6
Xian 6
Auburn Hills 5
Brasília 5
Duque de Caxias 5
Hangzhou 5
Istanbul 5
Nuremberg 5
Redmond 5
São José 5
Totale 11.870
Nome #
Modulating D-amino acid oxidase substrate specificity: production of an enzyme for analytical determination of all D-amino acids by directed evolution 211
A biosensor for all D-amino acids using evolved D-amino acid oxidase 202
Characterization of human D-amino acid oxidase 196
Relevance of weak flavin binding in human D-amino acid oxidase 189
Investigating the role of active site residues of Rhodotorula gracilis D-amino acid oxidase on its substrate specificity. 188
Catalytic properties of D-amino acid oxidase in cephalosporin C bioconversion: A comparison between proteins from different sources 187
Contribution of the dimeric state to the thermal stability of the flavoprotein D-amino acid oxidase 184
Active site and reaction mechanism of Rhodotorula gracilis D-amino acid oxidase: a crystallographic and site-directed mutagenesis approach 180
Analyzing the d-amino acid content in biological samples by engineered enzymes 177
Dissecting the structural determinants of the stability of cholesterol oxidase containing covalently bound flavin 171
The role of tyrosines 223 and 238 in Rhodotorula gracilis D-amino acid oxidase catalysis: Interpretation of double mutations 169
Optimization of glutaryl-7-aminocephalosporanic acid acylase expression in E.coli 169
Expression in Escherichia coli and in vitro refolding of the human protein pLG72 167
Yeast D-amino acid oxidase: structural basis of its catalytic properties 161
Evolution of an acylase active on cephalosporin C 160
Active site and reaction mechanism of Rhodotorula gracilis D-amino acid oxidase:a crystallographic and site-directed mutagenesis approach 159
A "molten globule"-like intermediate in the unfolding of the peroxisomal flavoprotein D-amino acid oxidase 159
Active site of yeast D-amino acid oxidase: mutations and inferences 155
Active site of yeast D-amino acid oxidase:mutations and inferences 155
D-amino acid oxidase: new findings 154
Characterization of a D-amino acid oxidase microbiosensor for D-serine detection in the central nervous system. 154
Physiological functions of D-amino acid oxidases: from yeast to humans. 151
Kinetic mechanisms of glycine oxidase from Bacillus subtilis 149
The x-ray structure of D-amino acid oxidase at very high resolution identifies the chemical mechanism of flavin-dependent substrate dehydrogenation 146
Tryptophan 243 affects interprotein contacts, cofactor binding and stability in D-amino acid oxidase from Rhodotorula gracilis 146
Yeast D-amino acid oxidase: Structural basis of its catalytic properties 145
On the oxygen reactivity of cholesterol oxidase. 142
Studies on the reaction mechanism of Rhodotorula gracilis D-amino-acid oxidase - Role of the highly conserved Tyr-223 on substrate binding and catalysis 142
Redox potentials and their pH dependence of D-amino-acid oxidase of Rhodotorula gracilis and Trigonopsis variabilis 142
Properties and applications of microbial D-amino acid oxidases: Current state and perspectives 142
Characterization of a yeast D-amino acid oxidase microbiosensor for D-serine detection in the central nervous system 142
Yeast D-amino acid oxidase: structural basis of its catalytic properties 141
D-amino acid oxidase as an industrial biocatalyst 140
Glycine oxidase from Bacillus subtilis: Role of Histidine 244 and Methionine 261. 138
Glycine oxidase from Bacillus subtilis - Characterization of a new flavoprotein 136
Role of tyrosine 238 in the active site of Rhodotorula gracilis D-amino acid oxidase - A site-directed mutagenesis study 135
Characterization of the new flavoprotein glycine oxidase from Bacillus subtilis 133
A "molten globule" - like intermediate in the unfolding of the flavoprotein D-amino acid oxidase 133
Effect of the oligomerization state on the thermal stability of yeast D-amino acid oxidase 132
Characterization of the new flavoprotein glycine oxidase from Bacillus subtilis 132
Unfolding intermediate in the peroxisomal flavoprotein D-amino acid oxidase 130
Dissection of the structural determinants involved in formation of the dimeric form of D-amino acid oxidase from Rhodotorula gracilis: role of the size of the beta F5-beta F6 loop 129
Kinetic mechanisms of cholesterol oxidase from Streptomyces hygroscopicus and Brevibacterium sterolicum 128
Structure-function relationships in glycine oxidase from Bacillus subtilis 128
Ruolo della dimerizzazione nel flavoenzima D-amino acido ossidasi da Rhodotorula gracilis 127
Structure and function of Rhodotorula gracilis D-amino acid oxidase. 1. Site-directed mutagenesis of tyrosines 223 and 238 126
Regulation of D-amino acid oxidase expression in the yeast Rhodotorula gracilis 126
On the mechanism of Rhodotorula gracilis D-amino acid oxidase: role of the active site serine 335 126
Evolution of novel enzyme specificities from a common scaffold 126
Detection of D-amino acids by D-amino acid oxidase. 124
Engineering the substrate specificity of D-amino-acid oxidase 124
Cholesterol oxidase from Brevibacterium sterolicum and Streptomices hygroscopicus: a covalent FAD binding vs. a non-covalent one 123
Biocatalysis and biocatalyst production 123
Conversion of the dimeric D-amino acid oxidase from Rhodotorula gracilis to a monomeric form. A rational mutagenesis approach 121
Characterization of D-Amino Acid Oxidase Microbiosensor for D-Serina detection in the central nervous system. 121
Glycine oxiadse from Bacillus subtilis: role of the histidine 244 and methionine 261 121
Role of the highly conserved Tyr223 and Tyr238 of yeast D-amino acid oxidase 120
Evolution of a Cephalosporin C Acylase. 119
Investigating the metabolic role of glycine oxidase from Bacillus subtilis 119
Modulation of the oxygen affinity of D-amino acid oxidase: production of evolved variants for a cancer enzyme 117
Site-directed mutagenesis and thermodynamic studies reveal the role of dimeric oligomerization state in yeast D-amino acid oxidase 115
Cloning and characterization of human and Xenopus allantoicase 114
Reaction mechanism of glycine oxidase, a new flavoenzyme active on glycine 113
Examination of pLG72 and D-Amino Acid Oxidase interaction as molecular basis of Schizophrenia. 113
Characterization of human D-amino acid oxidase, a flavoenzyme involved in neurotransmission regulation 112
pLG72 modulates intracellular D-serine levels through its interaction with D-amino acid oxidase - Effect on schizophrenia susceptibility 112
Structure-function correlation in glycine oxidase from Bacillus subtilis 112
Role of the C-terminal portion of yeast D-amino acid oxidase in stability and in aggregation state 111
Cholesterol oxidase from Brevibacterium sterolicum and Streptomyces hygroscopicus: a covalent FAD binding vs. a non-covalent one 111
Investigation of the oxygen reactivity if D-amino acid oxidase: production of evolved variants for gene therapy. 111
Very high resolution crystallographic structures of D-amino acid oxidase complexed with substrate and various ligands 110
Studies on the elimination reaction of Rhodotorula gracilis D-amino acid oxidase with beta-chloro-D-alanine 110
Structure-function relationships in glycine oxidase from Bacillus subtilis 110
In vivo studies on the D-amino acid oxidase-pLG72 interaction in human brain 110
Enzyme factory: engineering of new biocatalysts strating from a common scaffold. 110
Role of the highly conserved Tyr223 and Tyr238 of yeast D-amino acid oxidase 109
Engineering the substrate specificity of D-amino acid oxidase: a rational design approach 109
Cholesterol oxidase from Brevibacterium sterolicum - The relationship between covalent flavinylation and redox properties 108
Investigating D-Amino Acid Oxidase and pLG72 as potential targets of the antipsychotic drug chlorpromazine. 108
On the oxygen reactivity of flavoprotein oxidase. An oxygen access tunnel and gate in Brevibacterium sterolicum cholesterol oxidase. 108
Structure and function of Rhodothorula gracilis D-amino acid oxidase. 1. Site-directed mutagenesis of tyrosine 223 and 238 108
On the oxygen reactivity of flavooxidase 108
Engineering the substrate specificity of D-amino acid oxidase: a directed evolution approach 107
Engineering a new D-amino acid oxidase: an evoluted enzyme and its applications 107
Thermal stability of yeast D-amino acid oxidase: Deconvoluting the contributions of the dimeric aggregation state 107
Glycine oxidase from Bacillus subtilis: role of histidine 244 and methionine 261 107
Engineering the D-amino acid oxidase from Rhodotorula gracilis to facilitate its downstream processing 105
Investigating the molecular basis of schizophrenia: the effect of pLG72 interaction on the functionality of human D-amino acid oxidase 105
Combinatorial and computational challenges to design the substrate specificity of D-amino acid oxidase 105
Engineering the substrate specificity of D-amino acid oxidase by rational and irrational design 104
Reaction mechanism of flavin dehydrogenation by D-amino acid oxidase 104
Rational design of a novel specificity of D-amino acid oxidase: towards the biosensor for all D-amino acids? 103
Structure and function of Rhodotorula gracilis D-amino acid oxidase: site-directed mutagenesis of arginine 285 103
Overexpression of a recombinant wild-type and His-tagged Bacillus subtilis glycine oxidase in Escherichia coli 102
Very high resolution crystal structure of D-amino Acid oxidase. Insights into the reaction mechanism and mode of ligand binding 102
Techniques for the engineering of D-amino acid oxidase substrate specificity 102
Novel drugs for schizophrenia treatment: the mechanism of human D-amino acid oxidase inhibition 102
Role of the beta12-beta13 loop of yeast D-amino acid oxidase on stability and on aggregation: a rational design and thermodynamic study 100
Kinetic mechanism of glycine oxidase 100
Ligand-induced conformational changes in human D-amino acid oxidase 100
Totale 13.089
Categoria #
all - tutte 73.599
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 73.599


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.303 0 0 0 0 0 199 37 164 341 77 188 297
2021/20221.383 157 183 157 92 58 19 64 87 78 189 104 195
2022/20232.069 183 96 160 229 164 478 0 308 283 54 60 54
2023/20243.794 655 655 662 656 726 211 11 33 88 23 15 59
2024/20252.048 12 17 402 52 64 144 65 171 217 203 149 552
2025/20262.099 375 256 125 668 569 106 0 0 0 0 0 0
Totale 17.823