PILONE, MIRELLA
 Distribuzione geografica
Continente #
NA - Nord America 9.115
EU - Europa 6.940
AS - Asia 4.509
SA - Sud America 494
AF - Africa 61
Continente sconosciuto - Info sul continente non disponibili 38
OC - Oceania 17
Totale 21.174
Nazione #
US - Stati Uniti d'America 8.968
IT - Italia 3.418
SG - Singapore 1.342
UA - Ucraina 1.241
CN - Cina 1.040
TR - Turchia 765
VN - Vietnam 635
SE - Svezia 590
HK - Hong Kong 453
BR - Brasile 420
FI - Finlandia 377
DE - Germania 283
IE - Irlanda 252
FR - Francia 218
GB - Regno Unito 205
RU - Federazione Russa 155
IN - India 74
CA - Canada 68
JP - Giappone 68
MX - Messico 49
ES - Italia 33
CZ - Repubblica Ceca 31
BD - Bangladesh 28
ZA - Sudafrica 27
BE - Belgio 25
AR - Argentina 24
NL - Olanda 24
PL - Polonia 23
EU - Europa 17
IQ - Iraq 17
AU - Australia 15
CO - Colombia 15
LT - Lituania 13
PK - Pakistan 12
CL - Cile 10
AT - Austria 9
EC - Ecuador 9
IL - Israele 9
TN - Tunisia 8
CH - Svizzera 7
ID - Indonesia 7
JM - Giamaica 7
VE - Venezuela 7
AE - Emirati Arabi Uniti 6
BG - Bulgaria 6
KE - Kenya 6
SA - Arabia Saudita 6
AZ - Azerbaigian 5
CR - Costa Rica 5
DZ - Algeria 5
MA - Marocco 5
PT - Portogallo 5
UZ - Uzbekistan 5
JO - Giordania 4
KZ - Kazakistan 4
LU - Lussemburgo 4
MD - Moldavia 4
MY - Malesia 4
PA - Panama 4
PE - Perù 4
PH - Filippine 4
PR - Porto Rico 4
SY - Repubblica araba siriana 4
EG - Egitto 3
GT - Guatemala 3
HU - Ungheria 3
NG - Nigeria 3
NI - Nicaragua 3
RO - Romania 3
UY - Uruguay 3
AO - Angola 2
DO - Repubblica Dominicana 2
EE - Estonia 2
IR - Iran 2
LB - Libano 2
NP - Nepal 2
OM - Oman 2
PY - Paraguay 2
RS - Serbia 2
TT - Trinidad e Tobago 2
XK - ???statistics.table.value.countryCode.XK??? 2
AL - Albania 1
AM - Armenia 1
BH - Bahrain 1
BT - Bhutan 1
BY - Bielorussia 1
CY - Cipro 1
ET - Etiopia 1
GA - Gabon 1
GR - Grecia 1
HR - Croazia 1
KG - Kirghizistan 1
KI - Kiribati 1
LK - Sri Lanka 1
LV - Lettonia 1
MK - Macedonia 1
MN - Mongolia 1
MO - Macao, regione amministrativa speciale della Cina 1
NZ - Nuova Zelanda 1
PS - Palestinian Territory 1
Totale 21.154
Città #
Milan 2.565
Jacksonville 925
San Jose 922
Chandler 789
Singapore 701
Ashburn 594
Fairfield 511
Hong Kong 451
Izmir 383
Woodbridge 326
Dearborn 318
Princeton 312
Nyköping 309
Beijing 296
Wilmington 293
Council Bluffs 275
Dublin 250
Seattle 211
Ann Arbor 201
Dallas 194
Houston 193
Dong Ket 185
Chicago 184
Rome 184
Cambridge 181
Boardman 173
The Dalles 171
San Mateo 146
Lauterbourg 137
Ho Chi Minh City 103
Como 79
Los Angeles 73
New York 73
Orem 67
Hanoi 63
Ogden 62
Tokyo 60
Guangzhou 55
Santa Clara 52
Helsinki 50
São Paulo 47
San Diego 46
Kocaeli 39
Chennai 36
Hefei 34
Nanjing 34
Munich 31
Düsseldorf 30
Kunming 28
London 28
Washington 27
Manchester 26
Verona 25
Brussels 24
Tianjin 24
Toronto 24
Mexico City 23
Atlanta 22
Shanghai 22
Warsaw 21
Johannesburg 20
Montreal 19
Nanchang 19
Denver 18
Amsterdam 17
Brooklyn 17
Frankfurt am Main 17
Norwalk 17
Hangzhou 16
Olomouc 16
Turku 16
Haiphong 15
Poplar 15
Shenzhen 15
Jinan 14
Boston 13
Da Nang 13
Phoenix 13
Redwood City 13
San Francisco 13
Belo Horizonte 12
Brno 12
Curitiba 11
Rio de Janeiro 11
Ankara 10
Fuzhou 10
Memphis 10
Mumbai 10
Stockholm 9
Chongqing 8
Des Moines 8
New Delhi 8
Zhengzhou 8
Columbus 7
Shenyang 7
Wenzhou 7
Buenos Aires 6
Changsha 6
Edinburgh 6
Falls Church 6
Totale 14.196
Nome #
Modulating D-amino acid oxidase substrate specificity: production of an enzyme for analytical determination of all D-amino acids by directed evolution 233
Characterization of human D-amino acid oxidase 225
A biosensor for all D-amino acids using evolved D-amino acid oxidase 224
Contribution of the dimeric state to the thermal stability of the flavoprotein D-amino acid oxidase 215
Relevance of weak flavin binding in human D-amino acid oxidase 209
Investigating the role of active site residues of Rhodotorula gracilis D-amino acid oxidase on its substrate specificity. 207
Catalytic properties of D-amino acid oxidase in cephalosporin C bioconversion: A comparison between proteins from different sources 207
Analyzing the d-amino acid content in biological samples by engineered enzymes 204
Active site and reaction mechanism of Rhodotorula gracilis D-amino acid oxidase: a crystallographic and site-directed mutagenesis approach 199
Dissecting the structural determinants of the stability of cholesterol oxidase containing covalently bound flavin 198
Optimization of glutaryl-7-aminocephalosporanic acid acylase expression in E.coli 190
Evolution of an acylase active on cephalosporin C 187
A "molten globule"-like intermediate in the unfolding of the peroxisomal flavoprotein D-amino acid oxidase 187
Active site of yeast D-amino acid oxidase: mutations and inferences 186
Active site and reaction mechanism of Rhodotorula gracilis D-amino acid oxidase:a crystallographic and site-directed mutagenesis approach 185
Expression in Escherichia coli and in vitro refolding of the human protein pLG72 185
The role of tyrosines 223 and 238 in Rhodotorula gracilis D-amino acid oxidase catalysis: Interpretation of double mutations 185
Role of tyrosine 238 in the active site of Rhodotorula gracilis D-amino acid oxidase - A site-directed mutagenesis study 183
Yeast D-amino acid oxidase: structural basis of its catalytic properties 182
Active site of yeast D-amino acid oxidase:mutations and inferences 177
Physiological functions of D-amino acid oxidases: from yeast to humans. 176
Kinetic mechanisms of glycine oxidase from Bacillus subtilis 175
D-amino acid oxidase: new findings 175
Tryptophan 243 affects interprotein contacts, cofactor binding and stability in D-amino acid oxidase from Rhodotorula gracilis 175
Characterization of a D-amino acid oxidase microbiosensor for D-serine detection in the central nervous system. 174
The x-ray structure of D-amino acid oxidase at very high resolution identifies the chemical mechanism of flavin-dependent substrate dehydrogenation 172
Yeast D-amino acid oxidase: Structural basis of its catalytic properties 171
Characterization of a yeast D-amino acid oxidase microbiosensor for D-serine detection in the central nervous system 171
Characterization of the new flavoprotein glycine oxidase from Bacillus subtilis 168
Properties and applications of microbial D-amino acid oxidases: Current state and perspectives 167
Yeast D-amino acid oxidase: structural basis of its catalytic properties 165
Glycine oxidase from Bacillus subtilis - Characterization of a new flavoprotein 164
A "molten globule" - like intermediate in the unfolding of the flavoprotein D-amino acid oxidase 163
Kinetic mechanisms of cholesterol oxidase from Streptomyces hygroscopicus and Brevibacterium sterolicum 162
Characterization of the new flavoprotein glycine oxidase from Bacillus subtilis 159
Redox potentials and their pH dependence of D-amino-acid oxidase of Rhodotorula gracilis and Trigonopsis variabilis 159
Ruolo della dimerizzazione nel flavoenzima D-amino acido ossidasi da Rhodotorula gracilis 159
pLG72 modulates intracellular D-serine levels through its interaction with D-amino acid oxidase - Effect on schizophrenia susceptibility 159
On the oxygen reactivity of cholesterol oxidase. 157
Studies on the reaction mechanism of Rhodotorula gracilis D-amino-acid oxidase - Role of the highly conserved Tyr-223 on substrate binding and catalysis 157
Cholesterol oxidase from Brevibacterium sterolicum and Streptomices hygroscopicus: a covalent FAD binding vs. a non-covalent one 155
Glycine oxidase from Bacillus subtilis: Role of Histidine 244 and Methionine 261. 154
D-amino acid oxidase as an industrial biocatalyst 153
Regulation of D-amino acid oxidase expression in the yeast Rhodotorula gracilis 152
Engineering the substrate specificity of D-amino-acid oxidase 152
Dissection of the structural determinants involved in formation of the dimeric form of D-amino acid oxidase from Rhodotorula gracilis: role of the size of the beta F5-beta F6 loop 151
Evolution of a Cephalosporin C Acylase. 149
Structure-function relationships in glycine oxidase from Bacillus subtilis 148
Evolution of novel enzyme specificities from a common scaffold 148
Effect of the oligomerization state on the thermal stability of yeast D-amino acid oxidase 147
Conversion of the dimeric D-amino acid oxidase from Rhodotorula gracilis to a monomeric form. A rational mutagenesis approach 147
Biocatalysis and biocatalyst production 147
Unfolding intermediate in the peroxisomal flavoprotein D-amino acid oxidase 147
Cloning and characterization of human and Xenopus allantoicase 146
Detection of D-amino acids by D-amino acid oxidase. 146
Investigating the metabolic role of glycine oxidase from Bacillus subtilis 143
Structure and function of Rhodotorula gracilis D-amino acid oxidase. 1. Site-directed mutagenesis of tyrosines 223 and 238 142
Characterization of D-Amino Acid Oxidase Microbiosensor for D-Serina detection in the central nervous system. 142
On the oxygen reactivity of flavoprotein oxidase. An oxygen access tunnel and gate in Brevibacterium sterolicum cholesterol oxidase. 141
Glycine oxiadse from Bacillus subtilis: role of the histidine 244 and methionine 261 140
On the mechanism of Rhodotorula gracilis D-amino acid oxidase: role of the active site serine 335 140
Characterization of human D-amino acid oxidase, a flavoenzyme involved in neurotransmission regulation 139
Site-directed mutagenesis and thermodynamic studies reveal the role of dimeric oligomerization state in yeast D-amino acid oxidase 138
Engineering the substrate specificity of D-amino acid oxidase: a rational design approach 137
Role of the highly conserved Tyr223 and Tyr238 of yeast D-amino acid oxidase 137
Cholesterol oxidase from Brevibacterium sterolicum and Streptomyces hygroscopicus: a covalent FAD binding vs. a non-covalent one 136
Role of the highly conserved Tyr223 and Tyr238 of yeast D-amino acid oxidase 135
Investigating the molecular basis of schizophrenia: the effect of pLG72 interaction on the functionality of human D-amino acid oxidase 134
Structure and function of Rhodothorula gracilis D-amino acid oxidase. 1. Site-directed mutagenesis of tyrosine 223 and 238 134
Very high resolution crystallographic structures of D-amino acid oxidase complexed with substrate and various ligands 133
Examination of pLG72 and D-Amino Acid Oxidase interaction as molecular basis of Schizophrenia. 133
Modulation of the oxygen affinity of D-amino acid oxidase: production of evolved variants for a cancer enzyme therapy 133
Modulation of the oxygen affinity of D-amino acid oxidase: production of evolved variants for a cancer enzyme 132
Combinatorial and computational challenges to design the substrate specificity of D-amino acid oxidase 132
Engineering the substrate specificity of D-amino acid oxidase: a directed evolution approach 131
Studies on the elimination reaction of Rhodotorula gracilis D-amino acid oxidase with beta-chloro-D-alanine 131
Kinetic mechanism of glycine oxidase 131
Enzyme factory: engineering of new biocatalysts strating from a common scaffold. 131
Reaction mechanism of glycine oxidase, a new flavoenzyme active on glycine 130
Structure-function relationships in glycine oxidase from Bacillus subtilis 129
Structure-function correlation in glycine oxidase from Bacillus subtilis 129
Engineering the D-amino acid oxidase from Rhodotorula gracilis to facilitate its downstream processing 128
In vivo studies on the D-amino acid oxidase-pLG72 interaction in human brain 128
Engineering a new D-amino acid oxidase: an evoluted enzyme and its applications 127
Investigation of the oxygen reactivity if D-amino acid oxidase: production of evolved variants for gene therapy. 127
Cholesterol oxidase from Brevibacterium sterolicum - The relationship between covalent flavinylation and redox properties 126
Structure and function of Rhodotorula gracilis D-amino acid oxidase: site-directed mutagenesis of arginine 285 126
Glycine oxidase from Bacillus subtilis: role of histidine 244 and methionine 261 126
On the oxygen reactivity of flavooxidase 126
Engineering the substrate specificity of D-amino acid oxidase by rational and irrational design 125
Role of the C-terminal portion of yeast D-amino acid oxidase in stability and in aggregation state 125
Investigating D-Amino Acid Oxidase and pLG72 as potential targets of the antipsychotic drug chlorpromazine. 125
Novel drugs for schizophrenia treatment: the mechanism of human D-amino acid oxidase inhibition 125
Thermal stability of yeast D-amino acid oxidase: Deconvoluting the contributions of the dimeric aggregation state 124
Role of the beta12-beta13 loop of yeast D-amino acid oxidase on stability and on aggregation: a rational design and thermodynamic study 123
Reaction mechanism of flavin dehydrogenation by D-amino acid oxidase 122
Very high resolution crystal structure of D-amino Acid oxidase. Insights into the reaction mechanism and mode of ligand binding 122
Rational design of a novel specificity of D-amino acid oxidase: towards the biosensor for all D-amino acids? 121
Techniques for the engineering of D-amino acid oxidase substrate specificity 121
Reaction mechanism of glycine oxidase, a new flavoenzyme active on glycine 120
Totale 15.418
Categoria #
all - tutte 85.664
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 85.664


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.226 0 183 157 92 58 19 64 87 78 189 104 195
2022/20232.069 183 96 160 229 164 478 0 308 283 54 60 54
2023/20243.794 655 655 662 656 726 211 11 33 88 23 15 59
2024/20252.048 12 17 402 52 64 144 65 171 217 203 149 552
2025/20265.124 375 256 125 668 569 329 1.167 354 560 370 212 139
2026/2027326 104 222 0 0 0 0 0 0 0 0 0 0
Totale 21.174