statistiche ricercatore

PILONE, MIRELLA

Distribuzione geografica

Continente	#
NA - Nord America	8.410
EU - Europa	6.884
AS - Asia	4.470
SA - Sud America	479
AF - Africa	60
Continente sconosciuto - Info sul continente non disponibili	18
OC - Oceania	17
Totale	20.338

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Nazione	#
US - Stati Uniti d'America	8.298
IT - Italia	3.393
SG - Singapore	1.324
UA - Ucraina	1.241
CN - Cina	1.022
TR - Turchia	765
VN - Vietnam	635
SE - Svezia	579
HK - Hong Kong	453
BR - Brasile	414
FI - Finlandia	377
DE - Germania	283
IE - Irlanda	252
FR - Francia	216
GB - Regno Unito	203
RU - Federazione Russa	154
IN - India	74
JP - Giappone	65
CA - Canada	54
MX - Messico	48
CZ - Repubblica Ceca	30
BD - Bangladesh	28
ES - Italia	27
ZA - Sudafrica	27
BE - Belgio	24
AR - Argentina	22
NL - Olanda	22
PL - Polonia	21
EU - Europa	17
IQ - Iraq	17
AU - Australia	15
LT - Lituania	13
CO - Colombia	12
PK - Pakistan	12
AT - Austria	9
EC - Ecuador	9
IL - Israele	9
CL - Cile	8
TN - Tunisia	8
CH - Svizzera	7
ID - Indonesia	7
VE - Venezuela	7
AE - Emirati Arabi Uniti	6
BG - Bulgaria	6
KE - Kenya	6
SA - Arabia Saudita	6
AZ - Azerbaigian	5
DZ - Algeria	5
UZ - Uzbekistan	5
JO - Giordania	4
KZ - Kazakistan	4
LU - Lussemburgo	4
MA - Marocco	4
MY - Malesia	4
PA - Panama	4
PH - Filippine	4
PT - Portogallo	4
SY - Repubblica araba siriana	4
EG - Egitto	3
HU - Ungheria	3
NG - Nigeria	3
RO - Romania	3
UY - Uruguay	3
AO - Angola	2
DO - Repubblica Dominicana	2
EE - Estonia	2
IR - Iran	2
JM - Giamaica	2
LB - Libano	2
MD - Moldavia	2
NP - Nepal	2
OM - Oman	2
PE - Perù	2
PY - Paraguay	2
RS - Serbia	2
AL - Albania	1
AM - Armenia	1
BH - Bahrain	1
BT - Bhutan	1
BY - Bielorussia	1
CR - Costa Rica	1
CY - Cipro	1
ET - Etiopia	1
GA - Gabon	1
GR - Grecia	1
HR - Croazia	1
KG - Kirghizistan	1
KI - Kiribati	1
LK - Sri Lanka	1
LV - Lettonia	1
MK - Macedonia	1
MN - Mongolia	1
MO - Macao, regione amministrativa speciale della Cina	1
NI - Nicaragua	1
NZ - Nuova Zelanda	1
PS - Palestinian Territory	1
SK - Slovacchia (Repubblica Slovacca)	1
XK - ???statistics.table.value.countryCode.XK???	1
Totale	20.338

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Città	#
Milan	2.562
Jacksonville	925
Chandler	789
San Jose	777
Singapore	697
Ashburn	567
Fairfield	511
Hong Kong	451
Izmir	383
Woodbridge	326
Dearborn	318
Princeton	312
Nyköping	309
Wilmington	293
Beijing	291
Dublin	250
Seattle	209
Ann Arbor	201
Houston	188
Dallas	186
Dong Ket	185
Chicago	182
Cambridge	181
Rome	180
Boardman	173
The Dalles	170
San Mateo	145
Lauterbourg	137
Ho Chi Minh City	103
Como	79
Los Angeles	69
Orem	67
Hanoi	63
Ogden	62
New York	60
Tokyo	60
Guangzhou	55
Helsinki	50
São Paulo	47
San Diego	44
Santa Clara	42
Kocaeli	39
Chennai	36
Hefei	34
Nanjing	34
Council Bluffs	33
Munich	31
Düsseldorf	30
Kunming	28
London	28
Manchester	26
Washington	26
Verona	25
Brussels	24
Tianjin	24
Toronto	24
Mexico City	23
Shanghai	21
Warsaw	21
Atlanta	20
Johannesburg	20
Nanchang	19
Amsterdam	17
Brooklyn	17
Frankfurt am Main	17
Montreal	17
Norwalk	17
Denver	16
Hangzhou	16
Olomouc	16
Turku	16
Haiphong	15
Poplar	15
Shenzhen	15
Jinan	14
Boston	13
Da Nang	13
Redwood City	13
Brno	12
Belo Horizonte	11
Curitiba	11
Rio de Janeiro	11
San Francisco	11
Ankara	10
Fuzhou	10
Mumbai	10
Phoenix	9
Stockholm	9
Chongqing	8
Des Moines	8
New Delhi	8
Zhengzhou	8
Shenyang	7
Wenzhou	7
Buenos Aires	6
Changsha	6
Columbus	6
Edinburgh	6
Falls Church	6
Hải Dương	6
Totale	13.698

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Nome	#
Modulating D-amino acid oxidase substrate specificity: production of an enzyme for analytical determination of all D-amino acids by directed evolution	221
A biosensor for all D-amino acids using evolved D-amino acid oxidase	217
Characterization of human D-amino acid oxidase	216
Contribution of the dimeric state to the thermal stability of the flavoprotein D-amino acid oxidase	206
Relevance of weak flavin binding in human D-amino acid oxidase	205
Investigating the role of active site residues of Rhodotorula gracilis D-amino acid oxidase on its substrate specificity.	204
Analyzing the d-amino acid content in biological samples by engineered enzymes	201
Catalytic properties of D-amino acid oxidase in cephalosporin C bioconversion: A comparison between proteins from different sources	199
Active site and reaction mechanism of Rhodotorula gracilis D-amino acid oxidase: a crystallographic and site-directed mutagenesis approach	193
Dissecting the structural determinants of the stability of cholesterol oxidase containing covalently bound flavin	192
Optimization of glutaryl-7-aminocephalosporanic acid acylase expression in E.coli	183
A "molten globule"-like intermediate in the unfolding of the peroxisomal flavoprotein D-amino acid oxidase	183
Evolution of an acylase active on cephalosporin C	182
The role of tyrosines 223 and 238 in Rhodotorula gracilis D-amino acid oxidase catalysis: Interpretation of double mutations	182
Expression in Escherichia coli and in vitro refolding of the human protein pLG72	181
Active site and reaction mechanism of Rhodotorula gracilis D-amino acid oxidase:a crystallographic and site-directed mutagenesis approach	180
Active site of yeast D-amino acid oxidase: mutations and inferences	177
Yeast D-amino acid oxidase: structural basis of its catalytic properties	174
Kinetic mechanisms of glycine oxidase from Bacillus subtilis	173
Tryptophan 243 affects interprotein contacts, cofactor binding and stability in D-amino acid oxidase from Rhodotorula gracilis	172
Active site of yeast D-amino acid oxidase:mutations and inferences	172
The x-ray structure of D-amino acid oxidase at very high resolution identifies the chemical mechanism of flavin-dependent substrate dehydrogenation	170
D-amino acid oxidase: new findings	170
Characterization of a D-amino acid oxidase microbiosensor for D-serine detection in the central nervous system.	170
Role of tyrosine 238 in the active site of Rhodotorula gracilis D-amino acid oxidase - A site-directed mutagenesis study	167
Physiological functions of D-amino acid oxidases: from yeast to humans.	166
Yeast D-amino acid oxidase: Structural basis of its catalytic properties	164
Characterization of a yeast D-amino acid oxidase microbiosensor for D-serine detection in the central nervous system	164
Yeast D-amino acid oxidase: structural basis of its catalytic properties	162
Characterization of the new flavoprotein glycine oxidase from Bacillus subtilis	160
A "molten globule" - like intermediate in the unfolding of the flavoprotein D-amino acid oxidase	158
Redox potentials and their pH dependence of D-amino-acid oxidase of Rhodotorula gracilis and Trigonopsis variabilis	157
Properties and applications of microbial D-amino acid oxidases: Current state and perspectives	157
Glycine oxidase from Bacillus subtilis - Characterization of a new flavoprotein	155
On the oxygen reactivity of cholesterol oxidase.	154
Characterization of the new flavoprotein glycine oxidase from Bacillus subtilis	153
Studies on the reaction mechanism of Rhodotorula gracilis D-amino-acid oxidase - Role of the highly conserved Tyr-223 on substrate binding and catalysis	152
Ruolo della dimerizzazione nel flavoenzima D-amino acido ossidasi da Rhodotorula gracilis	151
D-amino acid oxidase as an industrial biocatalyst	150
Glycine oxidase from Bacillus subtilis: Role of Histidine 244 and Methionine 261.	150
Cholesterol oxidase from Brevibacterium sterolicum and Streptomices hygroscopicus: a covalent FAD binding vs. a non-covalent one	149
Regulation of D-amino acid oxidase expression in the yeast Rhodotorula gracilis	148
pLG72 modulates intracellular D-serine levels through its interaction with D-amino acid oxidase - Effect on schizophrenia susceptibility	147
Effect of the oligomerization state on the thermal stability of yeast D-amino acid oxidase	145
Structure-function relationships in glycine oxidase from Bacillus subtilis	145
Dissection of the structural determinants involved in formation of the dimeric form of D-amino acid oxidase from Rhodotorula gracilis: role of the size of the beta F5-beta F6 loop	144
Unfolding intermediate in the peroxisomal flavoprotein D-amino acid oxidase	144
Evolution of novel enzyme specificities from a common scaffold	143
Evolution of a Cephalosporin C Acylase.	142
Engineering the substrate specificity of D-amino-acid oxidase	142
Conversion of the dimeric D-amino acid oxidase from Rhodotorula gracilis to a monomeric form. A rational mutagenesis approach	141
Kinetic mechanisms of cholesterol oxidase from Streptomyces hygroscopicus and Brevibacterium sterolicum	141
Detection of D-amino acids by D-amino acid oxidase.	141
Biocatalysis and biocatalyst production	141
Structure and function of Rhodotorula gracilis D-amino acid oxidase. 1. Site-directed mutagenesis of tyrosines 223 and 238	139
Cloning and characterization of human and Xenopus allantoicase	138
Investigating the metabolic role of glycine oxidase from Bacillus subtilis	137
Characterization of D-Amino Acid Oxidase Microbiosensor for D-Serina detection in the central nervous system.	137
Site-directed mutagenesis and thermodynamic studies reveal the role of dimeric oligomerization state in yeast D-amino acid oxidase	135
On the mechanism of Rhodotorula gracilis D-amino acid oxidase: role of the active site serine 335	135
Glycine oxiadse from Bacillus subtilis: role of the histidine 244 and methionine 261	134
Engineering the substrate specificity of D-amino acid oxidase: a rational design approach	133
Role of the highly conserved Tyr223 and Tyr238 of yeast D-amino acid oxidase	133
Characterization of human D-amino acid oxidase, a flavoenzyme involved in neurotransmission regulation	133
Examination of pLG72 and D-Amino Acid Oxidase interaction as molecular basis of Schizophrenia.	132
Cholesterol oxidase from Brevibacterium sterolicum and Streptomyces hygroscopicus: a covalent FAD binding vs. a non-covalent one	131
On the oxygen reactivity of flavoprotein oxidase. An oxygen access tunnel and gate in Brevibacterium sterolicum cholesterol oxidase.	131
Structure and function of Rhodothorula gracilis D-amino acid oxidase. 1. Site-directed mutagenesis of tyrosine 223 and 238	131
Role of the highly conserved Tyr223 and Tyr238 of yeast D-amino acid oxidase	129
Investigating the molecular basis of schizophrenia: the effect of pLG72 interaction on the functionality of human D-amino acid oxidase	129
Very high resolution crystallographic structures of D-amino acid oxidase complexed with substrate and various ligands	128
Studies on the elimination reaction of Rhodotorula gracilis D-amino acid oxidase with beta-chloro-D-alanine	128
Enzyme factory: engineering of new biocatalysts strating from a common scaffold.	128
Modulation of the oxygen affinity of D-amino acid oxidase: production of evolved variants for a cancer enzyme	128
Kinetic mechanism of glycine oxidase	126
Reaction mechanism of glycine oxidase, a new flavoenzyme active on glycine	125
Structure-function correlation in glycine oxidase from Bacillus subtilis	125
Engineering the substrate specificity of D-amino acid oxidase: a directed evolution approach	123
Engineering a new D-amino acid oxidase: an evoluted enzyme and its applications	123
Role of the C-terminal portion of yeast D-amino acid oxidase in stability and in aggregation state	123
In vivo studies on the D-amino acid oxidase-pLG72 interaction in human brain	123
On the oxygen reactivity of flavooxidase	123
Cholesterol oxidase from Brevibacterium sterolicum - The relationship between covalent flavinylation and redox properties	122
Structure and function of Rhodotorula gracilis D-amino acid oxidase: site-directed mutagenesis of arginine 285	122
Engineering the D-amino acid oxidase from Rhodotorula gracilis to facilitate its downstream processing	122
Engineering the substrate specificity of D-amino acid oxidase by rational and irrational design	121
Thermal stability of yeast D-amino acid oxidase: Deconvoluting the contributions of the dimeric aggregation state	121
Structure-function relationships in glycine oxidase from Bacillus subtilis	121
Investigation of the oxygen reactivity if D-amino acid oxidase: production of evolved variants for gene therapy.	121
Glycine oxidase from Bacillus subtilis: role of histidine 244 and methionine 261	121
Investigating D-Amino Acid Oxidase and pLG72 as potential targets of the antipsychotic drug chlorpromazine.	120
Modulation of the oxygen affinity of D-amino acid oxidase: production of evolved variants for a cancer enzyme therapy	119
Combinatorial and computational challenges to design the substrate specificity of D-amino acid oxidase	119
Rational design of a novel specificity of D-amino acid oxidase: towards the biosensor for all D-amino acids?	118
Very high resolution crystal structure of D-amino Acid oxidase. Insights into the reaction mechanism and mode of ligand binding	118
Novel drugs for schizophrenia treatment: the mechanism of human D-amino acid oxidase inhibition	118
Overexpression of a recombinant wild-type and His-tagged Bacillus subtilis glycine oxidase in Escherichia coli	117
Reaction mechanism of flavin dehydrogenation by D-amino acid oxidase	116
Reaction mechanism of glycine oxidase, a new flavoenzyme active on glycine	116
Reaction mechanism of flavin dehydrogenation by D-amino acid oxidase	116
Totale	14.844

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Categoria	#
all - tutte	78.113
article - articoli	0
book - libri	0
conference - conferenze	0
curatela - curatele	0
other - altro	0
patent - brevetti	0
selected - selezionate	0
volume - volumi	0
Totale	78.113

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	Totale	Lug	Ago	Sett	Ott	Nov	Dic	Gen	Feb	Mar	Apr	Mag	Giu
2020/2021	562	0	0	0	0	0	0	0	0	0	77	188	297
2021/2022	1.383	157	183	157	92	58	19	64	87	78	189	104	195
2022/2023	2.069	183	96	160	229	164	478	0	308	283	54	60	54
2023/2024	3.794	655	655	662	656	726	211	11	33	88	23	15	59
2024/2025	2.048	12	17	402	52	64	144	65	171	217	203	149	552
2025/2026	4.633	375	256	125	668	569	329	1.167	354	560	230	0	0
Totale													20.357