statistiche ricercatore

PILONE, MIRELLA

Distribuzione geografica

Continente	#
EU - Europa	6.198
NA - Nord America	5.879
AS - Asia	1.481
Continente sconosciuto - Info sul continente non disponibili	17
OC - Oceania	4
SA - Sud America	4
Totale	13.583

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Nazione	#
US - Stati Uniti d'America	5.865
IT - Italia	3.359
UA - Ucraina	1.233
TR - Turchia	745
SE - Svezia	574
VN - Vietnam	367
CN - Cina	353
FI - Finlandia	316
IE - Irlanda	251
DE - Germania	229
GB - Regno Unito	117
FR - Francia	51
BE - Belgio	22
EU - Europa	17
CA - Canada	10
BG - Bulgaria	5
RU - Federazione Russa	5
ES - Italia	4
JP - Giappone	4
LU - Lussemburgo	4
AU - Australia	3
CH - Svizzera	3
CZ - Repubblica Ceca	3
IN - India	3
NL - Olanda	3
CL - Cile	2
EE - Estonia	2
HU - Ungheria	2
LT - Lituania	2
MX - Messico	2
PK - Pakistan	2
PL - Polonia	2
PT - Portogallo	2
RO - Romania	2
AE - Emirati Arabi Uniti	1
AR - Argentina	1
AT - Austria	1
BR - Brasile	1
BT - Bhutan	1
CR - Costa Rica	1
GR - Grecia	1
HR - Croazia	1
ID - Indonesia	1
IL - Israele	1
LV - Lettonia	1
MK - Macedonia	1
MO - Macao, regione amministrativa speciale della Cina	1
MY - Malesia	1
NZ - Nuova Zelanda	1
PA - Panama	1
RS - Serbia	1
SG - Singapore	1
SK - Slovacchia (Repubblica Slovacca)	1
Totale	13.583

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Città	#
Milan	2.557
Jacksonville	923
Chandler	789
Fairfield	511
Izmir	382
Woodbridge	326
Dearborn	318
Princeton	312
Nyköping	309
Wilmington	292
Ashburn	290
Dublin	250
Seattle	208
Ann Arbor	201
Dong Ket	185
Houston	182
Cambridge	181
Rome	178
San Mateo	145
Beijing	123
Como	79
Ogden	62
San Diego	44
Kocaeli	39
Hefei	32
Nanjing	31
Düsseldorf	30
Kunming	27
Verona	24
Washington	24
Brussels	22
Los Angeles	21
Nanchang	18
Boardman	17
Norwalk	17
Guangzhou	15
New York	14
Redwood City	13
Jinan	12
London	12
Toronto	8
Shenyang	7
Chongqing	6
Edinburgh	6
Falls Church	6
Parma	6
Xian	6
Auburn Hills	5
Fuzhou	5
Hangzhou	5
Helsinki	5
Redmond	5
Wenzhou	5
Dallas	4
Hebei	4
Monza	4
Sofia	4
Stockholm	4
Wuhan	4
Zhengzhou	4
Brighton	3
Changsha	3
Chicago	3
Frankfurt am Main	3
Madrid	3
Miami	3
Nanning	3
Pune	3
Trapani	3
Zurich	3
Acton	2
Amsterdam	2
Atlanta	2
Baotou	2
Bari	2
Besana in Brianza	2
Budapest	2
Casorezzo	2
Chengdu	2
Corsico	2
Harbin	2
Langfang	2
Leeds	2
Lisbon	2
Mcallen	2
New Bedfont	2
Nuremberg	2
Pakistan	2
Paris	2
Phoenix	2
Prescot	2
Shanghai	2
Signa	2
Sydney	2
Tallinn	2
Warsaw	2
Šiauliai	2
Abbiategrasso	1
Arconate	1
Ardea	1
Totale	9.405

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Nome	#
Modulating D-amino acid oxidase substrate specificity: production of an enzyme for analytical determination of all D-amino acids by directed evolution	176
Characterization of human D-amino acid oxidase	145
Investigating the role of active site residues of Rhodotorula gracilis D-amino acid oxidase on its substrate specificity.	142
A biosensor for all D-amino acids using evolved D-amino acid oxidase	141
Yeast D-amino acid oxidase: structural basis of its catalytic properties	139
Optimization of glutaryl-7-aminocephalosporanic acid acylase expression in E.coli	136
Expression in Escherichia coli and in vitro refolding of the human protein pLG72	134
Analyzing the d-amino acid content in biological samples by engineered enzymes	134
Dissecting the structural determinants of the stability of cholesterol oxidase containing covalently bound flavin	133
Catalytic properties of D-amino acid oxidase in cephalosporin C bioconversion: A comparison between proteins from different sources	133
Evolution of an acylase active on cephalosporin C	130
Relevance of weak flavin binding in human D-amino acid oxidase	130
Physiological functions of D-amino acid oxidases: from yeast to humans.	128
Kinetic mechanisms of glycine oxidase from Bacillus subtilis	127
Contribution of the dimeric state to the thermal stability of the flavoprotein D-amino acid oxidase	125
The role of tyrosines 223 and 238 in Rhodotorula gracilis D-amino acid oxidase catalysis: Interpretation of double mutations	125
D-amino acid oxidase: new findings	124
Tryptophan 243 affects interprotein contacts, cofactor binding and stability in D-amino acid oxidase from Rhodotorula gracilis	124
The x-ray structure of D-amino acid oxidase at very high resolution identifies the chemical mechanism of flavin-dependent substrate dehydrogenation	123
Redox potentials and their pH dependence of D-amino-acid oxidase of Rhodotorula gracilis and Trigonopsis variabilis	122
Studies on the reaction mechanism of Rhodotorula gracilis D-amino-acid oxidase - Role of the highly conserved Tyr-223 on substrate binding and catalysis	121
Yeast D-amino acid oxidase: Structural basis of its catalytic properties	119
On the oxygen reactivity of cholesterol oxidase.	118
Glycine oxidase from Bacillus subtilis: Role of Histidine 244 and Methionine 261.	118
Active site and reaction mechanism of Rhodotorula gracilis D-amino acid oxidase: a crystallographic and site-directed mutagenesis approach	118
Characterization of a D-amino acid oxidase microbiosensor for D-serine detection in the central nervous system.	117
Yeast D-amino acid oxidase: structural basis of its catalytic properties	115
Unfolding intermediate in the peroxisomal flavoprotein D-amino acid oxidase	114
D-amino acid oxidase as an industrial biocatalyst	113
Properties and applications of microbial D-amino acid oxidases: Current state and perspectives	113
Kinetic mechanisms of cholesterol oxidase from Streptomyces hygroscopicus and Brevibacterium sterolicum	111
Ruolo della dimerizzazione nel flavoenzima D-amino acido ossidasi da Rhodotorula gracilis	106
Evolution of novel enzyme specificities from a common scaffold	105
Characterization of a yeast D-amino acid oxidase microbiosensor for D-serine detection in the central nervous system	104
Active site of yeast D-amino acid oxidase:mutations and inferences	104
Effect of the oligomerization state on the thermal stability of yeast D-amino acid oxidase	103
Glycine oxiadse from Bacillus subtilis: role of the histidine 244 and methionine 261	103
Active site of yeast D-amino acid oxidase: mutations and inferences	101
Role of the highly conserved Tyr223 and Tyr238 of yeast D-amino acid oxidase	100
Glycine oxidase from Bacillus subtilis - Characterization of a new flavoprotein	100
On the mechanism of Rhodotorula gracilis D-amino acid oxidase: role of the active site serine 335	100
Regulation of D-amino acid oxidase expression in the yeast Rhodotorula gracilis	98
Engineering the substrate specificity of D-amino-acid oxidase	97
A "molten globule"-like intermediate in the unfolding of the peroxisomal flavoprotein D-amino acid oxidase	97
Role of tyrosine 238 in the active site of Rhodotorula gracilis D-amino acid oxidase - A site-directed mutagenesis study	94
Active site and reaction mechanism of Rhodotorula gracilis D-amino acid oxidase:a crystallographic and site-directed mutagenesis approach	93
Studies on the elimination reaction of Rhodotorula gracilis D-amino acid oxidase with beta-chloro-D-alanine	93
Engineering the substrate specificity of D-amino acid oxidase: a rational design approach	93
Role of the C-terminal portion of yeast D-amino acid oxidase in stability and in aggregation state	92
On the oxygen reactivity of flavooxidase	92
Very high resolution crystallographic structures of D-amino acid oxidase complexed with substrate and various ligands	91
Structure-function relationships in glycine oxidase from Bacillus subtilis	91
Investigation of the oxygen reactivity if D-amino acid oxidase: production of evolved variants for gene therapy.	91
Role of the highly conserved Tyr223 and Tyr238 of yeast D-amino acid oxidase	90
Site-directed mutagenesis and thermodynamic studies reveal the role of dimeric oligomerization state in yeast D-amino acid oxidase	89
Engineering a new D-amino acid oxidase: an evoluted enzyme and its applications	89
Engineering the D-amino acid oxidase from Rhodotorula gracilis to facilitate its downstream processing	89
Cholesterol oxidase from Brevibacterium sterolicum and Streptomices hygroscopicus: a covalent FAD binding vs. a non-covalent one	89
Enzyme factory: engineering of new biocatalysts strating from a common scaffold.	89
Engineering the substrate specificity of D-amino acid oxidase by rational and irrational design	88
Examination of pLG72 and D-Amino Acid Oxidase interaction as molecular basis of Schizophrenia.	88
Structure and function of Rhodotorula gracilis D-amino acid oxidase. 1. Site-directed mutagenesis of tyrosines 223 and 238	87
Engineering the substrate specificity of D-amino acid oxidase: a directed evolution approach	87
Cloning and characterization of human and Xenopus allantoicase	87
Thermal stability of yeast D-amino acid oxidase: Deconvoluting the contributions of the dimeric aggregation state	87
pLG72 modulates intracellular D-serine levels through its interaction with D-amino acid oxidase - Effect on schizophrenia susceptibility	86
On the oxygen reactivity of flavoprotein oxidase. An oxygen access tunnel and gate in Brevibacterium sterolicum cholesterol oxidase.	86
Combinatorial and computational challenges to design the substrate specificity of D-amino acid oxidase	86
Overexpression of a recombinant wild-type and His-tagged Bacillus subtilis glycine oxidase in Escherichia coli	85
Rational design of a novel specificity of D-amino acid oxidase: towards the biosensor for all D-amino acids?	85
Structure and function of Rhodotorula gracilis D-amino acid oxidase: site-directed mutagenesis of arginine 285	85
Cholesterol oxidase from Brevibacterium sterolicum and Streptomyces hygroscopicus: a covalent FAD binding vs. a non-covalent one	85
Glycine oxidase from Bacillus subtilis: role of histidine 244 and methionine 261	85
Characterization of the new flavoprotein glycine oxidase from Bacillus subtilis	84
Dissection of the structural determinants involved in formation of the dimeric form of D-amino acid oxidase from Rhodotorula gracilis: role of the size of the beta F5-beta F6 loop	83
Evolution of a Cephalosporin C Acylase.	83
Reaction mechanism of glycine oxidase, a new flavoenzyme active on glycine	82
Reaction mechanism of flavin dehydrogenation by D-amino acid oxidase	82
Characterization of D-Amino Acid Oxidase Microbiosensor for D-Serina detection in the central nervous system.	82
Investigating the molecular basis of schizophrenia: the effect of pLG72 interaction on the functionality of human D-amino acid oxidase	82
Role of the C-terminal portion of yeast D-amino acid oxidase in stability and aggregation state	81
Conversion of the dimeric D-amino acid oxidase from Rhodotorula gracilis to a monomeric form. A rational mutagenesis approach	81
Investigating the metabolic role of glycine oxidase from Bacillus subtilis	81
Cholesterol oxidase from Brevibacterium sterolicum - The relationship between covalent flavinylation and redox properties	80
Kinetic mechanism of cholesterol oxidase from Streptomyces hygroscopicus and Brevibacterium sterolicum	80
Investigating D-Amino Acid Oxidase and pLG72 as potential targets of the antipsychotic drug chlorpromazine.	80
Characterization of the new flavoprotein glycine oxidase from Bacillus subtilis	79
On the covalent link of the flavin cofactor in Cholesterol Oxidase.	79
Enzyme factory: engineering of new biocatalysts strating from a common scaffold	79
Structure-function relationships in glycine oxidase from Bacillus subtilis	78
A "molten globule" - like intermediate in the unfolding of the flavoprotein D-amino acid oxidase	78
Techniques for the engineering of D-amino acid oxidase substrate specificity	78
Ligand-induced conformational changes in human D-amino acid oxidase	78
Modulation of the oxygen affinity of D-amino acid oxidase: production of evolved variants for a cancer enzyme therapy	78
Reaction mechanism of flavin dehydrogenation by D-amino acid oxidase	77
Studies on the elimination reaction of Rhodotorula gracilis D-amino acid oxidase with beta-chloro-D-alanine	77
Kinetic mechanism of glycine oxidase	77
Ligand-induced conformational changes in human D-amino acid oxidase	76
Investigation of the oxygen reactivity of D-amino acid oxidase: production of tvolved variants for gene therapy.	76
Kinetic mechanism of glycine oxidase	75
Totale	9.984

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Categoria	#
all - tutte	40.324
article - articoli	0
book - libri	0
conference - conferenze	0
curatela - curatele	0
other - altro	0
patent - brevetti	0
selected - selezionate	0
volume - volumi	0
Totale	40.324

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	Totale	Lug	Ago	Sett	Ott	Nov	Dic	Gen	Feb	Mar	Apr	Mag	Giu
2018/2019	681	0	0	0	0	0	0	0	0	0	0	194	487
2019/2020	2.164	72	128	64	343	72	267	368	293	101	242	38	176
2020/2021	1.754	19	178	29	188	37	199	37	164	341	77	188	297
2021/2022	1.383	157	183	157	92	58	19	64	87	78	189	104	195
2022/2023	2.069	183	96	160	229	164	478	0	308	283	54	60	54
2023/2024	3.720	655	655	662	656	726	211	11	33	88	23	0	0
Totale													13.602